Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Joshua, Chiappelli"'
Autor:
Xiaoming Du, Fow-Sen Choa, Joshua Chiappelli, Heather Bruce, Mark Kvarta, Ann Summerfelt, Yizhou Ma, William T. Regenold, Kevin Walton, George F. Wittenberg, Stephanie Hare, Si Gao, Andrew van der Vaart, Zhiwei Zhao, Shuo Chen, Peter Kochunov, L. Elliot Hong
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 324-332 (2024)
The smoking rate is high in patients with schizophrenia. Brain stimulation targeting conventional brain circuits associated with nicotine addiction has also yielded mixed results. We aimed to identify alternative circuitries associated with nicotine
Externí odkaz:
https://doaj.org/article/19a62d0c0d86446e9e5578dccda7a876
Autor:
Yizhou Ma, Joshua Chiappelli, Mark D. Kvarta, Heather Bruce, Andrew van der Vaart, Eric L. Goldwaser, Xiaoming Du, Hemalatha Sampath, Samantha Lightner, Jane Endres, Akram Yusuf, Alexa Yuen, Samantha Narvaez, Danny Campos-Saravia, Peter Kochunov, L. Elliot Hong
Publikováno v:
Schizophrenia, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract We evaluated two models to link stressful life events (SLEs) with the psychopathology of schizophrenia spectrum disorders (SSD). We separated SLEs into independent (iSLEs, unlikely influenced by one’s behavior) and dependent (dSLEs, likely
Externí odkaz:
https://doaj.org/article/73e77d3ee4264ab1ac7459673a99692d
Autor:
Yizhou Ma, Mark D. Kvarta, Bhim M. Adhikari, Joshua Chiappelli, Xiaoming Du, Andrew van der Vaart, Eric L. Goldwaser, Heather Bruce, Kathryn S. Hatch, Si Gao, Ann Summerfelt, Neda Jahanshad, Paul M. Thompson, Thomas E. Nichols, L. Elliot Hong, Peter Kochunov
Publikováno v:
NeuroImage, Vol 265, Iss , Pp 119786- (2023)
Severe mental illnesses (SMIs) are often associated with compromised brain health, physical comorbidities, and cognitive deficits, but it is incompletely understood whether these comorbidities are intrinsic to SMI pathophysiology or secondary to havi
Externí odkaz:
https://doaj.org/article/98d8f4a4b6ea49deaa5df45e8681a0d2
Autor:
Bhim M. Adhikari, L. Elliot Hong, Zhiwei Zhao, Danny J.J. Wang, Paul M. Thompson, Neda Jahanshad, Alyssa H. Zhu, Stefan Holiga, Jessica A. Turner, Theo G.M. van Erp, Vince D. Calhoun, Kathryn S. Hatch, Heather Bruce, Stephanie M. Hare, Joshua Chiappelli, Eric L. Goldwaser, Mark D. Kvarta, Yizhou Ma, Xiaoming Du, Thomas E. Nichols, Alan R. Shuldiner, Braxton D. Mitchell, Juergen Dukart, Shuo Chen, Peter Kochunov
Publikováno v:
NeuroImage, Vol 262, Iss , Pp 119555- (2022)
Regional homogeneity (ReHo) is a measure of local functional brain connectivity that has been reported to be altered in a wide range of neuropsychiatric disorders. Computed from brain resting-state functional MRI time series, ReHo is also sensitive t
Externí odkaz:
https://doaj.org/article/9c9e989dc9704add82154764730818c5
Autor:
Junchao Huang, Jinghui Tong, Ping Zhang, Yanfang Zhou, Yimin Cui, Shuping Tan, Zhiren Wang, Fude Yang, Peter Kochunov, Joshua Chiappelli, Baopeng Tian, Li Tian, Yunlong Tan, L. Elliot Hong
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract A number of tryptophan metabolites known to be neuroactive have been examined for their potential associations with cognitive deficits in schizophrenia. Among these metabolites, kynurenic acid (KYNA), 5-hydroxyindole (5-HI), and quinolinic a
Externí odkaz:
https://doaj.org/article/fefde916e51341fcac0c9ec06c35d3c2
Autor:
Mark D. Kvarta, Heather A. Bruce, Joshua Chiappelli, Stephanie M. Hare, Eric L. Goldwaser, Jessica Sewell, Hemalatha Sampath, Samantha Lightner, Wyatt Marshall, Kathryn Hatch, Elizabeth Humphries, Seth Ament, Alan R. Shuldiner, Braxton D. Mitchell, Francis J. McMahon, Peter Kochunov, L. Elliot Hong
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Many psychiatric disorders including depression involve complex interactions of genetics and environmental stressors. Environmental influence is challenging to measure objectively and account for in genetic studies because the necessary larg
Externí odkaz:
https://doaj.org/article/12abe8ba34b44bb98f09d74d7e347960
Autor:
Shujuan Pan, Wei Feng, Yanli Li, Junchao Huang, Song Chen, Yimin Cui, Baopeng Tian, Shuping Tan, Zhiren Wang, Shangwu Yao, Joshua Chiappelli, Peter Kochunov, Shuo Chen, Fude Yang, Chiang-Shan R. Li, Li Tian, Yunlong Tan, L. Elliot Hong
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Cognitive impairment is a core characteristic of schizophrenia, but its underlying neural mechanisms remain poorly understood. Reduced brain-derived neurotrophic factor (BDNF), a protein critical for neural plasticity and synaptic signaling,
Externí odkaz:
https://doaj.org/article/cdc858b55e9945c2b596ca42c1d76373
Autor:
Joshua Chiappelli, Tiffany Beason
Publikováno v:
Journal of Nervous & Mental Disease. 211:95-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17cfb46eb4023a3a8545bc3f3acc2347
https://doi.org/10.1097/nmd.0000000000001602
https://doi.org/10.1097/nmd.0000000000001602
Autor:
Junchao, Huang, Jinghui, Tong, Ping, Zhang, Yanfang, Zhou, Yanli, Li, Shuping, Tan, Zhiren, Wang, Fude, Yang, Peter, Kochunov, Joshua, Chiappelli, Baopeng, Tian, Li, Tian, L Elliot, Hong, Yunlong, Tan
Publikováno v:
Brain, Behavior, and Immunity. 106:32-39
Patients with treatment-resistant schizophrenia (TRS) suffer severe, long-term psychotic symptoms and chronic stress. Salivary kynurenic acid (KYNA) and choroid plexus were evidenced to relate to psychological stress. We hypothesized that TRS patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904c00c34d9b0f472723db095d0b34c3
https://doi.org/10.1016/j.bbi.2022.08.001
https://doi.org/10.1016/j.bbi.2022.08.001
Autor:
Eric L. Goldwaser, Xiaoming Du, Bhim M. Adhikari, Mark Kvarta, Joshua Chiappelli, Stephanie Hare, Wyatt Marshall, Anya Savransky, Kathleen Carino, Heather Bruce, Ashley Acheson, Peter Kochunov, L. Elliot Hong
Publikováno v:
J Neuropsychiatry Clin Neurosci
Increased impulsivity is a hallmark trait of some neuropsychiatric illnesses, including addiction, traumatic brain injury, and externalizing disorders. The authors hypothesized that altered cerebral white matter microstructure may also underwrite nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1ec844b6d369c17db89c0cbbf64167
https://doi.org/10.1176/appi.neuropsych.21070167
https://doi.org/10.1176/appi.neuropsych.21070167