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pro vyhledávání: '"Josh Nichols"'
Autor:
Michael E. Østergaard, Josh Nichols, Timothy A. Dwight, Walt Lima, Michael E. Jung, Eric E. Swayze, Punit P. Seth
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 20-30 (2017)
Antisense oligonucleotides (ASOs) have the potential to discriminate between subtle RNA mismatches such as SNPs. Certain mismatches, however, allow ASOs to bind at physiological conditions and result in RNA cleavage mediated by RNase H. We showed tha
Externí odkaz:
https://doaj.org/article/7b40de9b51ff4177bdc0e4aee67af053
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101752 (2014)
To better understand the factors that influence the activity and specificity of antisense oligonucleotides (ASOs), we designed a minigene encoding superoxide dismutase 1 (SOD-1) and cloned the minigene into vectors for T7 transcription of pre-mRNA an
Externí odkaz:
https://doaj.org/article/2c773100b2994ebfb9f9401e512d914e
Autor:
Melhem Ghalib, Josh Nichols, Ihsan Al-Bayati, Sarah Al-Obaidi, Brian R. Davis, Richard W. McCallum, Irene Sarosiek
Publikováno v:
American Journal of Gastroenterology. 113:S1050-S1051
Publikováno v:
Mathematics Magazine. 69:238-239