Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Josh Morton"'
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Josh Morton, Alex Bunn, Martine Altidor, Sameul Mills, Sarah Evans, Monique Andersson, Mridula Rajwani
Publikováno v:
Clinical Infection in Practice, Vol 13, Iss , Pp 100117- (2022)
Patients infected with HIV benefit from early diagnosis, allowing initiation of highly effective treatment to reduce the risk of complications and onward infection.Current NICE guidelines recommend routine screening in all individuals accessing healt
Externí odkaz:
https://doaj.org/article/c884247729b640a6b7de5d85ef1757f3
Autor:
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1346 (2021)
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://doaj.org/article/d948abd924354895b2c5b1c46d082bd9
Autor:
Joshua M. Royal, Carrie A. Simpson, Alison A. McCormick, Amanda Phillips, Steve Hume, Josh Morton, John Shepherd, Youngjun Oh, Kelsi Swope, Jennifer L. DeBeauchamp, Richard J. Webby, Robert W. Cross, Viktoriya Borisevich, Thomas W. Geisbert, Jennifer K. Demarco, Barry Bratcher, Hugh Haydon, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1347 (2021)
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://doaj.org/article/43b61c27594a4cee8b9a7611a625c5e8
Autor:
Tsepo Lebiletsa Tsekoa, Therese Lotter-Stark, Sindisiwe Buthelezi, Ereck Chakauya, Stoyan H Stoychev, Claude Sabeta, Wonderful Shumba, Baby Phahladira, Steve Hume, Josh Morton, Charles E Rupprecht, Herta Steinkellner, Michael Pauly, Larry Zeitlin, Kevin Whaley, Rachel Chikwamba
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159313 (2016)
Rabies is a neglected zoonotic disease that has no effective treatment after onset of illness. However the disease can be prevented effectively by prompt administration of post exposure prophylaxis which includes administration of passive immunizing
Externí odkaz:
https://doaj.org/article/15078b4d36a44f1c8c99a86de7f30e3c
Autor:
Andrea R. Thurman, Thomas R. Moench, Marshall Hoke, Joseph A. Politch, Howard Cabral, Emilie Mausser, Ellena Nador, Josh Morton, Krystal Hamorsky, Kelsi Swope, Barry Bratcher, Deborah J. Anderson, Kevin J. Whaley
Publikováno v:
American Journal of Obstetrics and Gynecology.
Autor:
John Palfreyman, Josh Morton
Publikováno v:
Journal of Strategic Contracting and Negotiation. 6:26-36
Digital transformation drives sustained business value through the use of digital technology. However, there is often confusion regarding what steps organisations should follow to achieve digital transformation, including to benefit innovation proces
Publikováno v:
Academy of Management Proceedings. 2022
Autor:
Christopher Golding, Jacqueline Jing You, Mathew Hughes, Trenton A. Williams, Folajimi Yesir Ashiru, Josh Morton, Christopher Williams, Franklin Nakpodia, Aljona Zorina
Publikováno v:
Academy of Management Proceedings. 2022
Autor:
Kelsi, Swope, Josh, Morton, Gregory P, Pogue, Steve, Hume, Michael H, Pauly, John, Shepherd, Carrie A, Simpson, Barry, Bratcher, Kevin J, Whaley, Larry, Zeitlin, Keith R, Davis, Hugh, Haydon
Publikováno v:
Methods in enzymology. 660
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky