Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Josh Houlton"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4817 (2022)
Stroke-induced cognitive impairments remain of significant concern, with very few treatment options available. The involvement of glycosaminoglycans in neuroregenerative processes is becoming better understood and recent advancements in technology ha
Externí odkaz:
https://doaj.org/article/c896c483759445d2ba38205262075338
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Stroke remains the leading cause of long-term disability with limited options available to aid in recovery. Significant effort has been made to try and minimize neuronal damage following stroke with use of neuroprotective agents, however, these treat
Externí odkaz:
https://doaj.org/article/7c1ef61c06d1416497c859ba11ef8c90
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. Young and aged brains show dif
Externí odkaz:
https://doaj.org/article/dac2e9ee5327498790b343f51b6a645b
Autor:
Petra S. van Nieuwenhuijzen, Kim Parker, Vivian Liao, Josh Houlton, Hye-Lim Kim, Graham A. R. Johnston, Jane R. Hanrahan, Mary Chebib, Andrew N. Clarkson
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 315 (2021)
Ischemic stroke remains a leading cause of disability worldwide, with limited treatment options available. This study investigates GABAC receptors as novel pharmacological targets for stroke recovery. The expression of ρ1 and ρ2 mRNA in mice were d
Externí odkaz:
https://doaj.org/article/3640c36cb0b343eb8f7421cca0d8369e
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f855d2165f4ce07d8087a1da732448
https://doi.org/10.1007/978-1-0716-2926-0_26
https://doi.org/10.1007/978-1-0716-2926-0_26
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2019 (2019)
Neural Plasticity, Vol 2019 (2019)
Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. Young and aged brains show dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58761c6c389311b90556e60d1e66334e
https://doi.org/10.1155/2019/1460890
https://doi.org/10.1155/2019/1460890
Autor:
Petra S, van Nieuwenhuijzen, Kim, Parker, Vivian, Liao, Josh, Houlton, Hye-Lim, Kim, Graham A R, Johnston, Jane R, Hanrahan, Mary, Chebib, Andrew N, Clarkson
Publikováno v:
Brain Sciences
Ischemic stroke remains a leading cause of disability worldwide, with limited treatment options available. This study investigates GABAC receptors as novel pharmacological targets for stroke recovery. The expression of ρ1 and ρ2 mRNA in mice were d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ceca0eb2fda39974117195b23abecbe
https://pubmed.ncbi.nlm.nih.gov/33801560
https://pubmed.ncbi.nlm.nih.gov/33801560
Autor:
Anita Barzegar-Fallah, Josh Houlton, M. Azam Ali, Deanna Barwick, Amin Shavandi, Andrew N. Clarkson, Houman Alimoradi
The minimal therapeutic impact observed following nanoparticle delivery directly correlates to the inability of nanoparticles to overcome biological barriers such as mucosal membranes and glycocalyx, cell membranes and cellular internalization, clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840ebdf28639b196146166044bbdb52a
https://doi.org/10.1016/b978-0-12-820466-5.00019-3
https://doi.org/10.1016/b978-0-12-820466-5.00019-3
Autor:
Geeske M. van Woerden, Christian D. Kelstrup, Emma K. Gowing, Inge S. Villumsen, Anders B. Klein, Birgitte Rahbek Kornum, Christine L. Gee, Nane Griem-Krey, Mohamed A. Shehata, Ulrike Leurs, Rasmus P. Clausen, Stine J. Gauger, Andrew N. Clarkson, Louise Hamborg, Anne Sofie G. Larsen, Chris C. Chi, Robert O. Burnie, Anders Bach, D. Steven Kerr, Jesper V. Olsen, Sara Marie Øie Solbak, Petrine Wellendorph, John Kuriyan, Ethan D McSpadden, Josh Houlton, Stine B. Vogensen, Selina M. W. Teurlings, Bente Frølund, Line B. Palmelund
Publikováno v:
Leurs, U, Klein, A B, McSpadden, E D, Griem-Krey, N, Solbak, S M O, Houlton, J, Villumsen, I S, Vogensen, S B, Hamborg, L, Gauger, S J, Palmelund, L B, Larsen, A S G, Shehata, M A, Kelstrup, C D, Olsen, J V, Bach, A, Burnie, R O, Kerr, D S, Gowing, E K, Teurlings, S M W, Chi, C C, Gee, C L, Frølund, B, Kornum, B R, van Woerden, G M, Clausen, R P, Kuriyan, J, Clarkson, A N & Wellendorph, P 2021, ' GHB analogs confer neuroprotection through specific interaction with the CaMKII alpha hub domain ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 31 . https://doi.org/10.1073/pnas.2108079118
Proceedings of the National Academy of Sciences of the United States of America, 118(31):e2108079118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Proceedings of the National Academy of Sciences of the United States of America, 118(31):e2108079118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Significance GHB is a natural brain metabolite of GABA, previously reported to be neuroprotective. However, the high-affinity binding site for GHB has remained elusive for almost 40 y. We here unveil CaMKIIα, a highly important neuronal kinase, as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3968f82757f44ca335598be37cbc1e0
https://curis.ku.dk/portal/da/publications/ghb-analogs-confer-neuroprotection-through-specific-interaction-with-the-camkii-alpha-hub-domain(df178a50-331d-40f4-ae3d-8333cff82958).html
https://curis.ku.dk/portal/da/publications/ghb-analogs-confer-neuroprotection-through-specific-interaction-with-the-camkii-alpha-hub-domain(df178a50-331d-40f4-ae3d-8333cff82958).html
Autor:
Elham Ahmadian, Amit Alexander, M. Azam Ali, Houman Alimoradi, Haifa Alkhalifa, Esraa Alshebber, José L. Arias, Fatemah Bahman, Ravi Bandaru, Deanna Barwick, Anita Barzegar-fallah, Raquel Campión, Catarina Cardoso, Hira Choudhury, Andrew N. Clarkson, Rambabu Dandela, S.C. Das, Laxmi Devi, Sunil K. Dubey, Aziz Eftekhari, Mazen M. El-Hammadi, Ahmed O. Elzoghby, Ana R. Fernandes, Praveen G., Maria L. Garcia, Bapi Gorain, Jorge Morales Gracia, Khaled Greish, Mayank Handa, Josh Houlton, Juan M. Irache, Nandakumar Kalarikkal, Omkar S. Kamble, Prashant Kesharwani, P. Khadka, Pramod Kumar, Ana Luisa Martínez-López, S. McGill, Margarida Miranda, Husna Mirza, Dinesh Kumar Mishra, Priya Mishra, Masumeh Mokhtarpour, Nagashekhara Molugulu, Ramakanta Naik, Isra Omar, Cristina Pangua, Tatiana N. Pashirova, Cristian Reboredo, Deviprasad Sahoo, Moemen M. Salama, Sara Salatin, Sangram Keshari Samal, Elena Sanchez-Lopez, A. Swaroop Sanket, R. Shah, Shahriar Shahi, Simin Sharifi, Amin Shavandi, Rahul Shukla, Amélia M. Silva, Dhirendra Pratap Singh, Sima Singh, Vijender Singh, Sreenivas Patro Sisinthy, H.D.C. Smyth, Maleki Dizaj Solmaz, Eliana B. Souto, Sebastien Taurin, Sabu Thomas, Rewati Raman Ujjwal, Nupur Vasdev, Carla Vitorino, Lucia Ya. Zakharova, Farrukh Zeeshan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e070f4385736d14cd0a1fd86ef4f36b
https://doi.org/10.1016/b978-0-12-820466-5.09992-0
https://doi.org/10.1016/b978-0-12-820466-5.09992-0