Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Josh E. Elias"'
Autor:
Lichao Zhang, Sebastian Winkler, Fabian P. Schlottmann, Oliver Kohlbacher, Josh E. Elias, Jan M. Skotheim, Jennifer C. Ewald
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The coordination of metabolism and growth with cell division is crucial for proliferation. While it has long been known that cell metabolism regulates the cell division cycle, it is becoming increasingly clear that the cell division cycle also regula
Externí odkaz:
https://doaj.org/article/fd6600d701c64a719785dac11d48a424
Methyltransferase-like 21C (METTL21C) methylates alanine tRNA synthetase at Lys-943 in muscle tissue
Publikováno v:
J Biol Chem
Protein-lysine methylation is a common posttranslational modification (PTM) throughout the human proteome that plays important roles in diverse biological processes. In humans, there are >100 known and candidate protein lysine methyltransferases (PKM
Autor:
Michael C. Lanz, Evgeny Zatulovskiy, Matthew P. Swaffer, Lichao Zhang, Ilayda Ilerten, Shuyuan Zhang, Dong Shin You, Georgi Marinov, Patrick McAlpine, Josh E. Elias, Jan M. Skotheim
Publikováno v:
Molecular cell. 82(17)
Cell size is tightly controlled in healthy tissues, but it is poorly understood how variations in cell size affect cell physiology. To address this, we employed a high-accuracy mass spectrometry-based approach to measure how the proteome changes with
Autor:
David A. Relman, Josh E. Elias, Kris Sankaran, Susan Holmes, Casavant E, Les Dethlefsen, Daniel D. Sprockett
Measuring host proteins through noninvasive stool-based assays opens new avenues for characterizing states of gastrointestinal health. However, the extent to which these proteins vary over time and between healthy subjects is poorly characterized. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6a4c40a9955a4b189c6bd1c30dcb35
https://doi.org/10.1101/551143
https://doi.org/10.1101/551143
Autor:
Dara Leto, Lei Zhang, Michael C. Bassik, Ron R. Kopito, Josh E. Elias, Christopher P. Walczak, David W. Morgens
SummaryThe ubiquitin proteasome system (UPS) maintains the integrity of the proteome and controls the abundance of key regulators of cellular function by selective protein degradation, but how foldingdefective proteins in the secretory system are sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c891e9b325c66dead6bcd6ce1f2fa8
Autor:
Kavya Swaminathan, Peder J Lund, Niclas Olsson, Caleb Marceau, Jan Carette, Mark M Davis, Josh E Elias
Publikováno v:
The Journal of Immunology. 196:46.5-46.5
Dengue (DEN) virus infection is a leading cause of hospitalization and death in the developing world and broadly effective vaccines and therapies remain elusive. Identifying infection-specific peptide antigens would open new avenues for developing T
Publikováno v:
Molecular cell. 50(1)
Summary The MRN (MRE11-RAD50-NBS1) complex has been implicated in many aspects of the DNA damage response. It has key roles in sensing and processing DNA double-strand breaks, as well as in activation of ATM (ataxia telangiectasia mutated). We reveal