Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Josephine R. Landrey"'
Publikováno v:
Journal of Biological Chemistry. 253:2361-2367
tives; however, the organism did not significantly metabo- lize the “left-handed” (Z)-17(20)-dehydrocholesterol in which C-22 is c&-oriented with respect to C-13. We interpret this to imply a stereochemical requirement for a right- handed side ch
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 5, Pp 770-777 (1981)
Cultures of Tetrahymena pyriformis were incubated with various sterols and the extent of dehydrogenation at C-7 and C-22 was determined. The sterols incubated were desmosterol, 22-dehydrodesmosterol, 24-methyldesmosterol, 24 alpha-methylcholesterol (
Publikováno v:
Lipids. 13:692-696
Many naturally occurring sterols are accumulated and metabolized byTetrahymena pyriformis. In most cases, the sterols are desaturated to giveΔ5,7,22-derivatives. Compounds with an ethyl, but not with a methyl, substituent at C-24 are dealkylated. Ex
Publikováno v:
Journal of Biological Chemistry. 250:6998-7005
The addition of ergosterol to cultures of Tetrahymena pyriformis results in (a) the accumulation of the sterol by the cells; (b) the inhibition of the synthesis of the pentacyclic triterpenoid alcohol, tetrahymanol; (c) the replacement of tetrahymano
Publikováno v:
The Journal of Protozoology. 29:105-109
The size and fatty acid composition of Tetrahymena pyriformis W cells were influenced by the provision of a nutritional supplement of ergosterol, cholesterol, or tetrahymanol, but not of 20-isocholesterol. Ergosterol and cholesterol addition led to a
Publikováno v:
Journal of Biological Chemistry. 255:11815-11821
The ciliated protozoan Tetrahymena pyriformis was incubated with delta 5-sterols which has side chains varying in degree of branching, polarity, and length. Branching at neither end of the side chain was obligatory for metabolism, although removal of
Autor:
John M. Joseph, John H. Adler, Rosemarie Marcaccio-Joseph, Robert L. Conner, Josephine R. Landrey, Katherine A. Erickson, Jeffrey T. Billheimer, William R. Nes, Karla S. Ritter
Publikováno v:
Lipids. 17:257-262
The delta 5-sterol, androst-5-en-3 beta-ol, which has no side chain at C-17, did not permit molting of the insect Heliothis zea, growth of either the protozoan Tetrahymena pyriformis, or the yeast Saccharomyces cerevisiae adapted to anaerobic conditi
Publikováno v:
Tetrahedron Letters. 9:6103-6106
Publikováno v:
Journal of Biological Chemistry. 244:2325-2333
The protozoan Tetrahymena pyriformis was incubated in a growth medium containing added unlabeled cholesterol or 26-14C-cholesterol with the following consequences: (a) the biosynthesis of tetrahymanol, a pentacyclic triterpenoid alcohol produced in t
Autor:
K.A. Ferguson, William R. Nes, Josephine R. Landrey, P.A. Govinda Malya, Robert L. Conner, Frank B. Mallory
Publikováno v:
Journal of Biological Chemistry. 246:561-568
Both ergosta-5,24(28)-dien-3β-ol and stigmasta-5,trans-24(28)-dien-3β-ol were metabolized in Tetrahymena pyriformis to give the respective Δ5,7,22,24(28)-tetraenes, vis. ergosta-5,7,trans-22,24(28)-tetraen-3β-ol and stigmasta-5,7,-trans-22,trans-