Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial: a mixed-methods study in India, Sri Lanka and Bangladesh

Autor: Vânia Oliveira, Jagadish Somanna, Jayashree Mondkar, Swati Manerkar, Mangalabharathi Sundaram, Paolo Montaldo, Josephine Mendoza, Paul Bassett, Siddarth Ramji, Seetha Shankaran, Sudhin Thayyil, Kerry Woolfall, Ismat Jahan, Mohammod Shahidullah, Rema Chandramohan, Monica Sebastian, Arasar Seeralar, Mohamed Sajjid, Ranmali Rodrigo, Samanmali Sumanasena, Stuti Pant, Naveen Benakappa, Samanmali P Sumanasena, Maya Annie Elias, Maria Moreno Morales, Bensitta Lincy, Chinnathambi N Kamalarathnam, Indramma Shivarudhrappa, Kumutha Jayaraman, Mythili Baburaj, Prathik Bandiya, Prakash Vinayagam, Radhika Sujatha, Sadeka C Moni, Saritha J Radha

Publikováno v: BMJ Global Health, Vol 6, Iss 5 (2021)

Introduction Time-critical neonatal trials in low-and-middle-income countries (LMICs) raise several ethical issues. Using a qualitative-dominant mixed-methods design, we explored informed consent process in Hypothermia for encephalopathy in low and m

Externí odkaz: https://doaj.org/article/8128304085594f4a9796a9b85b199eef

Early Postnatal Heart Rate Variability in Healthy Newborn Infants

Autor: Vânia Oliveira, Wilhelm von Rosenberg, Paolo Montaldo, Tricia Adjei, Josephine Mendoza, Vijayakumar Shivamurthappa, Danilo Mandic, Sudhin Thayyil

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

BackgroundDespite the increasing interest in fetal and neonatal heart rate variability (HRV) analysis and its potential use as a tool for early disease stratification, no studies have previously described the normal trends of HRV in healthy babies du

Externí odkaz: https://doaj.org/article/aa454ef72032465082d7fa0a2b6a5662

Preemptive Morphine During Therapeutic Hypothermia After Neonatal Encephalopathy: A Secondary Analysis

Autor: Natasha Liow, Seetha Shankaran, Sudhin Thayyil, Justinas Teiserskas, Vânia Oliveira, Rebeccah Slater, Paolo Montaldo, Josephine Mendoza, Paul Bassett, Peter J Lally

Publikováno v: Ther Hypothermia Temp Manag

Although therapeutic hypothermia (TH) improves outcomes after neonatal encephalopathy (NE), the safety and efficacy of preemptive opioid sedation during cooling therapy is unclear. We performed a secondary analysis of the data from a large multicount

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7dd2344d298831fc61e9f89e15cfa7
https://doi.org/10.1089/ther.2018.0052

Hypothermia for moderate or severe neonatal encephalopathy in low and middle-income countries (HELIX): a randomised control trial in India, Sri Lanka and Bangladesh

Autor: Sudhin Thayyil, Stuti Pant, Paolo Montaldo, Deepika Shukla, Vania Oliveira, Phoebe Ivain, Paul Bassett, Ravi Swamy, Josephine Mendoza, Maria Moreno-Morales, Peter J Lally, Naveen Benakappa, Prathik Bandiya, Indramma Shivarudhrappa, Jagadish Somanna, Usha B Kantharajanna, Ankur Rajvanshi, Sowmya Krishnappa, Poovathumkal K Joby, Kumutha Jayaraman, Rema Chandramohan, Chinnathambi N Kamalarathnam, Monica Sebastian, Indumathi A Tamilselvam, Usha D Rajendran, Radhakrishnan Soundrarajan, Vignesh Kumar, Harish Sudarsanan, Padmesh Vadakepat, Kavitha Gopalan, Mangalabharathi Sundaram, Arasar Seeralar, Prakash Vinayagam, Mohamed Sajjid, Mythili Baburaj, Kanchana D Murugan, Babu P Sathyanathan, Elumalai S Kumaran, Jayashree Mondkar, Swati Manerkar, Anagha R Joshi, Kapil Dewang, Swapnil M Bhisikar, Pavan Kalamdani, Vrushali Bichkar, Saikat Patra, Kapil Jiwnani, Mohammod Shahidullah, Sadeka C Moni, Ismat Jahan, Mohammad A Mannan, Sanjoy K Dey, Mst N Nahar, Mohammad N Islam, Kamrul H Shabuj, Ranmali Rodrigo, Samanmali Sumanasena, Thilini Abayabandara-Herath, Gayani K Chathurangika, Jithangi Wanigasinghe, Radhika Sujatha, Sobhakumar Saraswathy, Aswathy Rahul, Saritha J Radha, Manoj K Sarojam, Vaisakh Krishnan, Mohandas K Nair, Sahana Devadas, Savitha Chandriah, Harini Venkateswaran, Constance Burgod, Manigandan Chandrasekaran, Gaurav Atreja, Pallavi Muraleedharan, Jethro A Herberg, W K Kling Chong, Neil J Sebire, Ronit Pressler, Siddarth Ramji, Seetha Shankaran, Peter J. Lally, Usha B. Kantharajanna, Poovathumkal K. Joby, Chinnathambi N. Kamalarathnam, Indumathi Tamilselvam, Ushadevi Rajendran, Kanchana D. Murugan, Babu P. Sathyanathan, Elumalai S. Kumaran, Anagha R. Joshi, Swapnil M. Bhisikar, Sadeka C. Moni, Mohammad A. Mannan, Sanjoy K. Dey, Mst. N. Nahar, Manoj K. Sarojam, Mohandas K. Nair, Jethro A. Herberg, WK 'Kling' Chong, Neil J. Sebire

Publikováno v: e1285
e1273
The Lancet. Global Health

Summary Background Although therapeutic hypothermia reduces death or disability after neonatal encephalopathy in high-income countries, its safety and efficacy in low-income and middle-income countries is unclear. We aimed to examine whether therapeu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d944a6879a202e0de0f3a06df5fc05
http://hdl.handle.net/10044/1/90153

Pre-emptive opioid sedation during therapeutic hypothermia

Autor: Anuj Vakharia, Vania Oliveira, Theodora Markati, Sudhin Thayyil, Phoebe Ivain, Josephine Mendoza, Paolo Montaldo, Seetha Shankaran

Morphine is commonly used in neonates with hypothermic ischemic encephalopathy (HIE) during therapeutic hypothermia to provide comfort and analgesia. However, pharmacokinetic data to support morphine dosing in this vulnerable population are lacking.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9611036e1a027d68b4a0a55adfe05bd5
http://hdl.handle.net/10044/1/69853