Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Josephine M Forbes"'
Autor:
Estifanos Baye, Maximilian PJ de Courten, Karen Walker, Sanjeeva Ranasinha, Arul Earnest, Josephine M Forbes, Barbora de Courten
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract Diets high in advanced glycation end products (AGEs) are thought to be detrimental to cardiovascular health. However, there remains uncertainty about the beneficial effect of a low AGE diet on cardiovascular risk factors and inflammatory mar
Externí odkaz:
https://doaj.org/article/438955c088b14e79ae87222b52f6027d
Autor:
Sherman S. Leung, Nataliya Lenchik, Clayton Mathews, Alberto Pugliese, Domenica A. McCarthy, Selena Le Bagge, Adam Ewing, Mark Harris, Kristen J. Radford, Danielle J. Borg, Ivan Gerling, Josephine M. Forbes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Hypoglycemia in type 1 diabetes associates with changes in the pancreatic islet α cells, where the receptor for advanced glycation end products (RAGE) is highly expressed. This study compared islet RAGE expression in donors without diabetes
Externí odkaz:
https://doaj.org/article/1e61b2e4072243548923a79cf1259cab
Autor:
Kurt T. K. Giuliani, Anca Grivei, Purba Nag, Xiangju Wang, Melissa Rist, Katrina Kildey, Becker Law, Monica S. Ng, Ray Wilkinson, Jacobus Ungerer, Josephine M. Forbes, Helen Healy, Andrew J. Kassianos
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Inflammasomes are multiprotein platforms responsible for the release of pro-inflammatory cytokines interleukin (IL)-1β and IL-18. Mouse studies have identified inflammasome activation within dendritic cells (DC) as pivotal for driving tubul
Externí odkaz:
https://doaj.org/article/3f6627c645814f06a5a8676f3b366cb9
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 590-597 (2019)
Glucose metabolism in the kidney is currently foremost in the minds of nephrologists, diabetologists and researchers globally, as a result of the outstanding success of SGLT2 inhibitors in reducing renal and cardiovascular disease in individuals with
Externí odkaz:
https://doaj.org/article/e76075a8a4874b5094d0f282a292504d
Autor:
David Sturgess, Josephine M. Forbes, Jeff S. Coombes, Helen L. Barrett, Kye Gregory, Debbie Tolcher, Ra'eesa Doola, Alwyn S Todd, Casper G. Schalkwijk, Adam M. Deane, Satomi Okano
Publikováno v:
Journal of Human Nutrition and Dietetics, 35(3), 455-465. Wiley
Background Hyperglycaemia occurs frequently in the critically ill. Dietary intake of advanced glycation end-products (AGEs), specifically N epsilon-(carboxymethyl)lysine (CML), may exacerbate hyperglycaemia through perturbation of insulin sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a9ea3e2dbc09a00dda647b07ba1f73
https://doi.org/10.1111/jhn.12959
https://doi.org/10.1111/jhn.12959
Autor:
Irina Buckle, Josephine M. Forbes
Type 1 diabetes (T1DM) is an autoimmune disorder resulting in destruction of the insulin producing pancreatic β-cells that reside in the Islets of Langerhans. Despite significant progress in the understanding of T1DM pathogenesis, some fundamental c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f237d8aaa20784297cecfa849ea136
https://mts.intechopen.com/articles/show/title/the-role-of-the-receptor-for-advanced-glycation-endproducts-rage-in-type-1-diabetes-an-immune-cell-p
https://mts.intechopen.com/articles/show/title/the-role-of-the-receptor-for-advanced-glycation-endproducts-rage-in-type-1-diabetes-an-immune-cell-p
Autor:
Chenping Du, Rani O. Whiddett, Irina Buckle, Chen Chen, Josephine M. Forbes, Amelia K. Fotheringham
Publikováno v:
Cells. 11(21)
Type 1 diabetes (T1D) is an autoimmune disease in which the β-cells of the pancreas are attacked by the host’s immune system, ultimately resulting in hyperglycemia. It is a complex multifactorial disease postulated to result from a combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be7fae6c532ed89d8581249d8223366
https://pubmed.ncbi.nlm.nih.gov/36359899
https://pubmed.ncbi.nlm.nih.gov/36359899
Autor:
Glen P Lockwood, Josephine M. Forbes, Belinda Yau, Alistair M. Senior, Amanda E. Brandon, Samantha M. Solon-Biet, David Raubenheimer, Rosilene V Ribeiro, John F. O'Sullivan, David G. Le Couteur, Alison W S Luk, Kim S. Bell-Anderson, Gregory J. Cooney, Annabelle J. Milner, Andrew J. Holmes, Harrison J. W. Facey, Mitchell A. Sullivan, Jibran A Wali, Victoria C. Cogger, Stephen J. Simpson, Melkam A. Kebede, Tamara Pulpitel, Tim Dodgson, Laurence Macia, Yen Chin Koay, Devin Wahl
Publikováno v:
Nature Metabolism. 3:810-828
Reduced protein intake, through dilution with carbohydrate, extends lifespan and improves mid-life metabolic health in animal models. However, with transition to industrialised food systems, reduced dietary protein is associated with poor health outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2813152821895f4a1a3108ecbf5de92c
https://doi.org/10.1038/s42255-021-00393-9
https://doi.org/10.1038/s42255-021-00393-9
Autor:
Sherman S. Leung, Danielle J. Borg, Domenica A. McCarthy, Tamar E. Boursalian, Justen Cracraft, Aowen Zhuang, Amelia K. Fotheringham, Nicole Flemming, Thomas Watkins, John J. Miles, Per-Henrik Groop, Jean L. Scheijen, Casper G. Schalkwijk, Raymond J. Steptoe, Kristen J. Radford, Mikael Knip, Josephine M. Forbes
Publikováno v:
Diabetes, 71(9), 1994-2008. American Diabetes Association
Type 1 diabetes (T1D) is an autoimmune disease with no cure, where clinical translation of promising therapeutics has been hampered by the reproducibility crisis. Here, short-term administration of an antagonist to the receptor for advanced glycation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd3e8333caaa65906e3300828b73aed
https://doi.org/10.2337/figshare.20051633.v1
https://doi.org/10.2337/figshare.20051633.v1
Publikováno v:
Nutrients. 14(13)
Since the 1980s, chronic kidney disease (CKD) affecting all ages has increased by almost 25%. This increase may be partially attributable to lifestyle changes and increased global consumption of a “western” diet, which is typically energy dense,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45462010192677fe92c038718d0f043
https://pubmed.ncbi.nlm.nih.gov/35807857
https://pubmed.ncbi.nlm.nih.gov/35807857