Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Josephine E. Haddon"'
Autor:
Josephine E. Haddon, Daniel Titherage, Julia R. Heckenast, Jennifer Carter, Michael J. Owen, Jeremy Hall, Lawrence S. Wilkinson, Matthew W. Jones
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Impaired behavioural flexibility is a core feature of neuropsychiatric disorders and is associated with underlying dysfunction of fronto-striatal circuitry. Reduced dosage of Cyfip1 is a risk factor for neuropsychiatric disorder, as evidence
Externí odkaz:
https://doaj.org/article/ff9feaf84b2d4dadb10bfac41d15a835
Autor:
Ana I. Silva, Josephine E. Haddon, Yasir Ahmed Syed, Simon Trent, Tzu-Ching E. Lin, Yateen Patel, Jenny Carter, Niels Haan, Robert C. Honey, Trevor Humby, Yaniv Assaf, Michael J. Owen, David E. J. Linden, Jeremy Hall, Lawrence S. Wilkinson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
People with a genetic deletion of the 15q11.2 locus are at increased risk for psychiatric disorders and white matter disturbances, but the gene(s) responsible are unclear. Here, the authors show that low dosage of CYFIP1, present in the human 15q11.2
Externí odkaz:
https://doaj.org/article/411296870f6b40bf8e1be35dea45f741
Autor:
Josephine E. Haddon, David N. George
Publikováno v:
Journal of Experimental Psychology: Animal Learning and Cognition. 47:48-62
In 5 experiments, we assessed the effects of preexposure to simple auditory stimuli on subsequent conditioning and discrimination learning. Experiment 1 showed that preexposure to a single stimulus retarded acquisition of conditioned responding to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b877300323be510c09822d0f636b59
https://doi.org/10.1037/xan0000266
https://doi.org/10.1037/xan0000266
Publikováno v:
Journal of Experimental Psychology: Animal Behavior Processes. 39:14-23
Four experiments with rats examined the origin of outcome-selective Pavlovian-to-instrumental transfer (PIT). Experiment 1 used a standard procedure, where outcomes were embedded within extended conditioned stimuli (CSs), to demonstrate the basic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d230e72da9e1a0ab5e72f96f509148
https://doi.org/10.1037/a0030594
https://doi.org/10.1037/a0030594
Autor:
Simon Killcross, Josephine E. Haddon
Publikováno v:
Neuroscience. 199:205-212
Previous research suggests the infralimbic cortex is important in situations when there is competition between goal-directed and habitual responding. Here we used a response conflict procedure to further explore the involvement of the infralimbic cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cbb2d8b1260bdd0b2306c30af39f98
https://doi.org/10.1016/j.neuroscience.2011.09.065
https://doi.org/10.1016/j.neuroscience.2011.09.065
Autor:
Simon Killcross, Josephine E. Haddon
Publikováno v:
Behavioral Neuroscience. 125:344-349
It has been proposed that the cognitive dysfunction observed in patients with schizophrenia reflects a failure in cognitive control, in particular an inability to use task-relevant information to guide behavior. Using a prefrontal-dependent task desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3d52af9e8b5f0993781a83327e7589
https://doi.org/10.1037/a0023572
https://doi.org/10.1037/a0023572
Autor:
Christopher McGowan, Simon Killcross, Lois Grayson, David N. George, Robert Colin Honey, Josephine E. Haddon
Publikováno v:
Quarterly Journal of Experimental Psychology. 64:1-9
Cognitive impairments in schizophrenia have been characterized as reflecting a core deficit in the maintenance or use of task-setting cues to mediate appropriate ongoing behaviour. This analysis suggests that cognitive deficits in schizophrenia will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de826bcb2f078f6b652560a0c8c8de2d
https://doi.org/10.1080/17470218.2010.529579
https://doi.org/10.1080/17470218.2010.529579
Publikováno v:
European Journal of Neuroscience. 25:559-566
One fundamental function of the prefrontal cortex (PFC) is to guide context-appropriate behaviour in situations of response conflict. Haddon and Killcross recently developed a task in rats which mimics some aspects of response conflict seen in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f8f2cb9c77765dabb02407170a4b6e
https://doi.org/10.1111/j.1460-9568.2006.05295.x
https://doi.org/10.1111/j.1460-9568.2006.05295.x
Autor:
Josephine E. Haddon, Simon Killcross
Publikováno v:
Neural Networks. 19:1192-1202
Rats were trained on two biconditional discrimination tasks, in two different contexts, and were rewarded with two different outcomes. At test, they received presentations of audiovisual compounds of these training stimuli, in extinction. These compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a0ca090805c509228b5fa9da0d5eea
https://doi.org/10.1016/j.neunet.2006.04.004
https://doi.org/10.1016/j.neunet.2006.04.004
Autor:
Josephine E. Haddon, Simon Killcross
Publikováno v:
The Journal of Neuroscience. 26:2933-2940
The prefrontal cortex has been implicated in multiple forms of goal-directed behavior. Rats with pretraining lesions to the prefrontal cortex (PFC) or specific lesions to the anterior cingulate cortex (ACC) were trained and tested on a novel behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ab23bbd2cd447baa87b235c37fd30b
https://doi.org/10.1523/jneurosci.3243-05.2006
https://doi.org/10.1523/jneurosci.3243-05.2006