Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Josephine E. Clark-Curtiss"'
Autor:
Vandana Malhotra, Blessing P. Okon, Akash T. Satsangi, Sumana Das, Uchenna Watson Waturuocha, Atul Vashist, Josephine E. Clark-Curtiss, Deepak Kumar Saini
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT The Mycobacterium tuberculosis protein kinase K regulates growth adaptation by facilitating mycobacterial survival in response to a variety of in vitro and in vivo stress conditions. Here, we further add that pknK transcription is responsive
Externí odkaz:
https://doaj.org/article/33465f73a711408995890dda598d9e1f
Autor:
Blessing P. Okon, Emilia Fields, Matthew Brovold, Xiao Wang, Roy Curtiss, Greg Golden, Wei Kong, Tiana Golding, Amanda Gonzales, Josephine E. Clark-Curtiss, Gary Wilkins, Mark C. Jenkins
Publikováno v:
Avian Diseases. 64
A programmed self-destructive Salmonella vaccine delivery system was developed to facilitate efficient colonization in host tissues that allows release of the bacterial cell contents after lysis to stimulate mucosal, systemic, and cellular immunities
Publikováno v:
The Journal of Immunology. 200:39-48
Vaccines afford a better and more cost-effective approach to combatting infectious diseases than continued reliance on antibiotics or antiviral or antiparasite drugs in the current era of increasing incidences of diseases caused by drug-resistant pat
Autor:
Atul Vashist, Gunjan Sharma, Josephine E. Clark-Curtiss, Jaya Sivaswami Tyagi, Vandana Malhotra
The DevR response regulator of Mycobacterium tuberculosis is an established regulator of the dormancy response in mycobacteria and can also be activated during aerobic growth conditions in avirulent strains, suggesting a complex regulatory system. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9313afe5e973503a225530a58303846
https://europepmc.org/articles/PMC6200940/
https://europepmc.org/articles/PMC6200940/
Autor:
Tammi R. Duncan, Josephine E. Clark-Curtiss, Ruchi Agrawal, Deepak Kumar Saini, Vandana Malhotra
Publikováno v:
Journal of Biological Chemistry. 290:8294-8309
Mycobacterium tuberculosis genes Rv0844c/Rv0845 encoding the NarL response regulator and NarS histidine kinase are hypothesized to constitute a two-component system involved in the regulation of nitrate metabolism. However, there is no experimental e
Autor:
I. I. I. Roy Curtiss, Michael L. Fisher, Kenneth L. Roland, Chang-Ho Baek, Dorothy J. Dankel, Roger Strand, Ana Delgado, Karen E. Brenneman, Josephine E. Clark-Curtiss, Javier Santander
Publikováno v:
Nanoethics
NanoEthics
NanoEthics
Researchers have iterated that the future of synthetic biology and biotechnology lies in novel consumer applications of crossing biology with engineering. However, if the new biology’s future is to be sustainable, early and serious efforts must be
Autor:
Josephine E. Clark-Curtiss, María Dolores Juárez-Rodríguez, Roy Curtiss, Lourdes T. Arteaga-Cortés, Rebin Kader
Publikováno v:
Infection and Immunity. 80:798-814
Tuberculosis remains a global health threat, and there is dire need to develop a vaccine that is safe and efficacious and confers long-lasting protection. In this study, we constructed recombinant attenuated Salmonella vaccine (RASV) strains with pla
Publikováno v:
Tuberculosis. 89:169-174
The DevR transcriptional switch that defines the response of Mycobacterium tuberculosis to the lack of oxygen is now well established and likely helps the bacteria shift to a state of persistence. The M. tuberculosis two component signal transduction
Publikováno v:
FEMS Microbiology Letters. 236:341-347
Publikováno v:
Annual Review of Microbiology. 57:517-549
▪ Abstract Tuberculosis (TB) has afflicted humankind throughout history. Approximately one third of the world's population is currently infected with Mycobacterium tuberculosis and nearly two million people die of TB annually. Although much has bee