Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Josephine Bunch"'
Autor:
Alex Dexter, Dimitrios Tsikritsis, Natalie A. Belsey, Spencer A. Thomas, Jenny Venton, Josephine Bunch, Marina Romanchikova
Publikováno v:
Journal of Molecular Pathology, Vol 3, Iss 3, Pp 168-181 (2022)
Digital pathology is revolutionising the analysis of histological features and is becoming more and more widespread in both the clinic and research. Molecular pathology extends the tissue morphology information provided by conventional histopathology
Externí odkaz:
https://doaj.org/article/f13033b1294e4748a06c222097a58975
Publikováno v:
Metabolites, Vol 13, Iss 5, p 669 (2023)
Mass spectrometry imaging (MSI) has been a key driver of groundbreaking discoveries in a number of fields since its inception more than 50 years ago. Recently, MSI development trends have shifted towards ambient MSI (AMSI) as the removal of sample-pr
Externí odkaz:
https://doaj.org/article/c75cf6c0c7f84282a2af35e38b532456
Autor:
Catia Costa, Janella De Jesus, Chelsea Nikula, Teresa Murta, Geoffrey W. Grime, Vladimir Palitsin, Véronique Dartois, Kaya Firat, Roger Webb, Josephine Bunch, Melanie J. Bailey
Publikováno v:
Metabolites, Vol 13, Iss 2, p 262 (2023)
The colocation of elemental species with host biomolecules such as lipids and metabolites may shed new light on the dysregulation of metabolic pathways and how these affect disease pathogeneses. Alkali metals have been the subject of extensive resear
Externí odkaz:
https://doaj.org/article/0b3966024e5f424e9abf005fd18016b7
Autor:
Heather E. Hulme, Lynsey M. Meikle, Hannah Wessel, Nicole Strittmatter, John Swales, Carolyn Thomson, Anna Nilsson, Robert J. B. Nibbs, Simon Milling, Per E. Andren, C. Logan Mackay, Alex Dexter, Josephine Bunch, Richard J. A. Goodwin, Richard Burchmore, Daniel M. Wall
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) wit
Externí odkaz:
https://doaj.org/article/3a24c8a8c4bd40bd88a9c66a0de21e92
Autor:
Aateka Patel, Ewelina Hoffman, Doug Ball, Jan Klapwijk, Rory T. Steven, Alex Dexter, Josephine Bunch, Daniel Baker, Darragh Murnane, Victoria Hutter, Clive Page, Lea Ann Dailey, Ben Forbes
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 345 (2019)
‘Foamy’ alveolar macrophages (FAM) observed in nonclinical toxicology studies during inhaled drug development may indicate drug-induced phospholipidosis, but can also derive from adaptive non-adverse mechanisms. Orally administered amiodarone is
Externí odkaz:
https://doaj.org/article/44dbe4fdc29849178e81e17d591fdd1c
Autor:
Catia Costa, Janella de Jesus, Chelsea Nikula, Teresa Murta, Geoffrey W. Grime, Vladimir Palitsin, Roger Webb, Richard J. A. Goodwin, Josephine Bunch, Melanie Jane Bailey
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:2263-2272
Characterizing proton beam damage in biological materials is of interest to enable the integration of proton microprobe elemental mapping techniques with other imaging modalities. It is also of relevance to obtain a deeper understanding of mechanical
Autor:
Rory T. Steven, Marcel Niehaus, Adam J. Taylor, Ammar Nasif, Efstathios Elia, Richard J. A. Goodwin, Zoltan Takats, Josephine Bunch
Publikováno v:
Analytical Chemistry. 94:9970-9974
Mass spectrometry imaging (MSI) encompasses a powerful suit of techniques which provide spatially resolved atomic and molecular information from almost any sample type. MSI is now widely used in preclinical research to provide insight into metabolic
Autor:
Vincen Wu, Jocelyn Tillner, Emrys Jones, James S. McKenzie, Dipa Gurung, Anna Mroz, Liam Poynter, Daniel Simon, Cristina Grau, Xavier Altafaj, Marc-Emmanuel Dumas, Ian Gilmore, Josephine Bunch, Zoltan Takats
Publikováno v:
ANALYTICAL CHEMISTRY
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
In this study, we examine the suitability of desorption electro-flow focusing ionization (DEFFI) for mass spectrometry imaging (MSI) of biological tissue. We also compare the performance of desorption electrospray ionization (DESI) with and without t
Autor:
Daniel Simon, Gabriel Stefan Horkovics-Kovats, Yuchen Xiang, Julia Abda, Dimitris Papanastasiou, Hui-Yu Ho, Haixing Wang, Richard Schäffer, Tamas Karancsi, Anna Mroz, Laurine Lagache, Julia Balog, Isabelle Fournier, Josephine Bunch, Zoltan Takats
Laser desorption ionisation (LDI) is generally considered to be an inferior ionisation modality to matrix assisted LDI (MALDI), providing information solely on lipids with low sensitivity. The current study demonstrates that the combination of ambien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62daee523fe80b4bc301d73f2fc4bbdf
https://doi.org/10.26434/chemrxiv-2023-p2g9h-v2
https://doi.org/10.26434/chemrxiv-2023-p2g9h-v2
Autor:
Johan Vande Voorde, Arafath K. Najumudeen, Rory T. Steven, Chelsea J. Nikula, Alex Dexter, Lucas B. Zeiger, Efstathios A. Elia, Ammar Nasif, Ariadna Gonzalez-Fernandez, Teresa Murta, Michael Gillespie, Catriona A. Ford, Tamsin R.M. Lannagan, Nikola Vlahov, Rachel A. Ridgway, Colin Nixon, Kathryn Gilroy, David M. Gay, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Yuchen Xiang, Engy Shokry, William Clark, Vivian S.W. Li, Simon T. Barry, Richard J.A. Goodwin, Zoltan Takats, Oliver D.K. Maddocks, David Sumpton, Mariia O. Yuneva, Andrew D. Campbell, Josephine Bunch, Owen J. Sansom
With colorectal cancer (CRC) being the second most common cause of cancer-related deaths worldwide1, there is an urgent need for better diagnostic tools and new, more targeted therapies. Here we used genetically engineered mouse models (GEMMs), and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d49a1f23b41d8dcc99c9cad29a72865
https://doi.org/10.1101/2023.03.12.531945
https://doi.org/10.1101/2023.03.12.531945