Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Josephine A. Wright"'
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia
Autor:
Candice R. Gurbatri, Georgette A. Radford, Laura Vrbanac, Jongwon Im, Elaine M. Thomas, Courtney Coker, Samuel R. Taylor, YoungUk Jang, Ayelet Sivan, Kyu Rhee, Anas A. Saleh, Tiffany Chien, Fereshteh Zandkarimi, Ioana Lia, Tamsin R. M. Lannagan, Tongtong Wang, Josephine A. Wright, Hiroki Kobayashi, Jia Q. Ng, Matt Lawrence, Tarik Sammour, Michelle Thomas, Mark Lewis, Lito Papanicolas, Joanne Perry, Tracy Fitzsimmons, Patricia Kaazan, Amanda Lim, Alexandra M. Stavropoulos, Dion A. Gouskos, Julie Marker, Cheri Ostroff, Geraint Rogers, Nicholas Arpaia, Daniel L. Worthley, Susan L. Woods, Tal Danino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Bioengineered probiotics enable new opportunities to improve colorectal cancer (CRC) screening, prevention and treatment. Here, first, we demonstrate selective colonization of colorectal adenomas after oral delivery of probiotic E. coli Niss
Externí odkaz:
https://doaj.org/article/16a3783ebc994816bc3440bb05df9c6f
Autor:
Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A. Wright, Tamsin R. M. Lannagan, Laura Vrbanac, Hiroki Kobayashi, Krystyna Gieniec, Jia Q. Ng, Souzaburo Ihara, Chris Mavrangelos, Yoku Hayakawa, Patrick Hughes, Daniel L. Worthley, Susan L. Woods
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The intestinal stroma provides an important microenvironment for immune cell activation. The perturbation of this tightly regulated process can lead to excessive inflammation. We know that upregulated Toll-like receptor 4 (TLR4) in the intes
Externí odkaz:
https://doaj.org/article/aebf352fe0324c3cb4059278bf6e460e
Publikováno v:
Cardiology Research and Practice, Vol 2012 (2012)
Cell-to-cell interactions via gap junctional communication and connexon hemichannels are involved in the pathogenesis of diabetes. Gap junctions are highly specialized transmembrane structures that are formed by connexon hemichannels, which are furth
Externí odkaz:
https://doaj.org/article/482e5e2ec0c04ca3b01bb4e4c510135b
Autor:
Stephen M. Ratchford, Kanokwan Bunsawat, Jeremy K. Alpenglow, Jia Zhao, Josephine B. Wright, John J. Ryan, D. Walter Wray
Publikováno v:
Journal of Applied Physiology. 134:328-338
The current investigation has demonstrated that l-Cit administration may improve brachial artery endothelium-dependent vasodilation, upper and lower limb microvascular function, and physical capacity in patients with HFpEF, highlighting the potential
Autor:
Candice R. Gurbatri, Georgette Radford, Laura Vrbanac, Courtney Coker, Jong-won Im, Samuel R. Taylor, YoungUk Jang, Ayelet Sivan, Kyu Rhee, Anas A. Saleh, Tiffany Chien, Fereshteh Zandkarimi, Ioana Lia, Tamsin RM Lannagan, Tongtong Wang, Josephine A Wright, Elaine Thomas, Hiroki Kobayashi, Jia Q Ng, Matt Lawrence, Tarik Sammour, Michelle Thomas, Mark Lewis, Lito Papanicolas, Joanne Perry, Tracy Fitzsimmons, Patricia Kaazan, Amanda Lim, Julie Marker, Cheri Ostroff, Geraint Rogers, Nicholas Arpaia, Daniel L Worthley, Susan L Woods, Tal Danino
Publikováno v:
bioRxiv
Bioengineered probiotics enable new opportunities to improve colorectal cancer (CRC) screening, prevention and treatment strategies. Here, we demonstrate the phenomenon of selective, long-term colonization of colorectal adenomas after oral delivery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa60062672f0b39d77dd9740b766a751
https://europepmc.org/articles/PMC10104002/
https://europepmc.org/articles/PMC10104002/
Autor:
Susan L. Woods, Robert G. Ramsay, Daniel L. Worthley, Alexander G. Heriot, Carla Grandori, Siddhartha Mukherjee, Jeanne Tie, Michael Michael, G. Adam Whitney, Shalini Pereira, Michael P. Flood, Peter J. Hewett, Julie Marker, Gayle X.Y. Tye, Timothy Price, Hiroki Kobayashi, Anne B. Richardson, Laura Vrbanac, Tamsin R.M. Lannagan, Rachele Rosati, Tongtong Wang, Michael Churchill, Josephine A. Wright, Vignesh Narasimhan
Peritonoid sensitivity to standard care chemotherapeutic regimens ex vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1914dfdc5ce1aab3efb5b75c924e721a
https://doi.org/10.1158/1078-0432.22475003.v1
https://doi.org/10.1158/1078-0432.22475003.v1
Autor:
Susan L. Woods, Robert G. Ramsay, Daniel L. Worthley, Alexander G. Heriot, Carla Grandori, Siddhartha Mukherjee, Jeanne Tie, Michael Michael, G. Adam Whitney, Shalini Pereira, Michael P. Flood, Peter J. Hewett, Julie Marker, Gayle X.Y. Tye, Timothy Price, Hiroki Kobayashi, Anne B. Richardson, Laura Vrbanac, Tamsin R.M. Lannagan, Rachele Rosati, Tongtong Wang, Michael Churchill, Josephine A. Wright, Vignesh Narasimhan
Purpose:Patients with colorectal cancer with peritoneal metastases (CRPMs) have limited treatment options and the lowest colorectal cancer survival rates. We aimed to determine whether organoid testing could help guide precision treatment for patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf344d1fef46cf1196a4ad616bf9fb0
https://doi.org/10.1158/1078-0432.c.6528956
https://doi.org/10.1158/1078-0432.c.6528956
Autor:
Susan L. Woods, Robert G. Ramsay, Daniel L. Worthley, Alexander G. Heriot, Carla Grandori, Siddhartha Mukherjee, Jeanne Tie, Michael Michael, G. Adam Whitney, Shalini Pereira, Michael P. Flood, Peter J. Hewett, Julie Marker, Gayle X.Y. Tye, Timothy Price, Hiroki Kobayashi, Anne B. Richardson, Laura Vrbanac, Tamsin R.M. Lannagan, Rachele Rosati, Tongtong Wang, Michael Churchill, Josephine A. Wright, Vignesh Narasimhan
Summary of drug panels and peritonoid genomic information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ef1e96e0673e6c1da4687fd57bca6f
https://doi.org/10.1158/1078-0432.22474994.v1
https://doi.org/10.1158/1078-0432.22474994.v1
Autor:
Susan L. Woods, Robert G. Ramsay, Daniel L. Worthley, Alexander G. Heriot, Carla Grandori, Siddhartha Mukherjee, Jeanne Tie, Michael Michael, G. Adam Whitney, Shalini Pereira, Michael P. Flood, Peter J. Hewett, Julie Marker, Gayle X.Y. Tye, Timothy Price, Hiroki Kobayashi, Anne B. Richardson, Laura Vrbanac, Tamsin R.M. Lannagan, Rachele Rosati, Tongtong Wang, Michael Churchill, Josephine A. Wright, Vignesh Narasimhan
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e24923a7ea1552a193fc96d68ad7a3f
https://doi.org/10.1158/1078-0432.22474997.v1
https://doi.org/10.1158/1078-0432.22474997.v1
Autor:
Stephen M, Ratchford, Kanokwan, Bunsawat, Jeremy K, Alpenglow, Jia, Zhao, Josephine B, Wright, John J, Ryan, D Walter, Wray
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985).
There is accumulating evidence for both peripheral vascular dysfunction and impaired functional capacity in patients with heart failure with a preserved ejection fraction (HFpEF). While derangements in the L-Arginine-nitric oxide (L-Arg-NO) pathway a