Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Josephine A. Hinneh"'
Autor:
Josephine A. Hinneh, Joanna L. Gillis, Nicole L. Moore, Lisa M. Butler, Margaret M. Centenera
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Receptor for hyaluronic acid-mediated motility (RHAMM) is a cell surface receptor for hyaluronic acid that is critical for cell migration and a cell cycle protein involved in microtubule assembly and stability. These functions of RHAMM are required f
Externí odkaz:
https://doaj.org/article/7407ac07a6cc44faaaa40e7fab0f5b04
Autor:
Joanna L Gillis, Josephine A Hinneh, Natalie K Ryan, Swati Irani, Max Moldovan, Lake-Ee Quek, Raj K Shrestha, Adrienne R Hanson, Jianling Xie, Andrew J Hoy, Jeff Holst, Margaret M Centenera, Ian G Mills, David J Lynn, Luke A Selth, Lisa M Butler
Publikováno v:
eLife, Vol 10 (2021)
Alterations to the androgen receptor (AR) signalling axis and cellular metabolism are hallmarks of prostate cancer. This study provides insight into both hallmarks by uncovering a novel link between AR and the pentose phosphate pathway (PPP). Specifi
Externí odkaz:
https://doaj.org/article/7b041890c6d2431cb95c6683b6ee5211
Autor:
Raj K Shrestha, Lake-Ee Quek, Joanna L. Gillis, Swati Irani, David J. Lynn, Jeff Holst, Margaret M. Centenera, Lisa M. Butler, Luke A. Selth, Ian G. Mills, Josephine A Hinneh, Max Moldovan, Adrienne R Hanson, Natalie K. Ryan, Andrew J. Hoy, Jianling Xie
Publikováno v:
eLife
eLife, Vol 10 (2021)
Gillis, J L, Hinneh, J A, Ryan, N K, Irani, S, Moldovan, M, Quek, L-E, Shrestha, R K, Hanson, A R, Xie, J, Hoy, A J, Holst, J, Centenera, M M, Mills, I G, Lynn, D J, Selth, L A & Butler, L M 2021, ' A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth ', eLife, vol. 10, e62592 . https://doi.org/10.7554/eLife.62592
eLife, Vol 10 (2021)
Gillis, J L, Hinneh, J A, Ryan, N K, Irani, S, Moldovan, M, Quek, L-E, Shrestha, R K, Hanson, A R, Xie, J, Hoy, A J, Holst, J, Centenera, M M, Mills, I G, Lynn, D J, Selth, L A & Butler, L M 2021, ' A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth ', eLife, vol. 10, e62592 . https://doi.org/10.7554/eLife.62592
Alterations to the androgen receptor (AR) signalling axis and cellular metabolism are hallmarks of prostate cancer. This study provides insight into both hallmarks by uncovering a novel link between AR and the pentose phosphate pathway (PPP). Specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530e601a3caf97dc159e8ad830211880
https://doi.org/10.7554/elife.62592
https://doi.org/10.7554/elife.62592
Autor:
Ian G. Mills, Joanna L. Gillis, Adrienne R. Hanson, Raj K Shrestha, Luke A. Selth, Margaret M. Centenera, Lisa M. Butler, Josephine A Hinneh, Lake-Ee Quek, David J. Lynn, Andrew J. Hoy, Jeff Holst, Swati Irani, Natalie K. Ryan, Max Moldovan, Jianling Xie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad1c106d7e160db1e228dce8fec5dd86
https://doi.org/10.7554/elife.62592.sa2
https://doi.org/10.7554/elife.62592.sa2
Autor:
Margaret M. Centenera, Lisa M. Butler, Lake-Ee Quek, Josephine A Hinneh, David J. Lynn, Joanna L. Gillis, Max Moldovan, Luke A. Selth, Andrew J. Hoy, Ian G. Mills, Raj K Shrestha, Natalie K. Ryan, Swati Irani, Jeff Holst
Alterations to androgen receptor (AR) signalling and cellular metabolism are hallmarks of prostate cancer. This study uncovers a novel link between AR and the pentose phosphate pathway (PPP) through 6-phosphogluoconate dehydrogenase (6PGD), an androg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bdbbea0a597ae89da8aae0f8f4fba2a
https://doi.org/10.1101/2020.09.02.279356
https://doi.org/10.1101/2020.09.02.279356
Autor:
Yoshiyuki Takei, Esteban C. Gabazza, Hajime Fujimoto, Corina N. D’Alessandro-Gabazza, Josephine A. Hinneh, Kazumasa Takao, M. Ohnishi, Taro Yasuma, Masaaki Toda, Kota Nishihama, K Yoshikawa, P Baffour Tonto, Osamu Taguchi, Tetsu Kobayashi, Yoshinori Takahashi, Toshiaki Totoki, Kentaro Fujiwara, M Yoshino, Atsushi Tomaru
Publikováno v:
Gene Therapy. 24:706-716
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with a median survival of 3-4 years after diagnosis. It is the most frequent form of a group of interstitial pneumonias of unknown etiology. Current available therapies prevent deterioration of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2428b7b525bf135e38c47126cf80fa45
https://doi.org/10.1038/gt.2017.80
https://doi.org/10.1038/gt.2017.80
Autor:
Josephine A. Hinneh, Isaac Cann, John Morser, Iwasa Motoh, Esteban C. Gabazza, Paloma Gil-Bernabe, Ziaurahman Roeen, Taro Yasuma, Corina N. D’Alessandro-Gabazza, Kota Nishihama, Yutaka Yano, Masaaki Toda, Tetsu Kobayashi, Rumi Mifuji-Moroka, Yoshiyuki Takei
Publikováno v:
Diabetes. 65:1940-1951
Protein S is an anticoagulant factor that also regulates inflammation and cell apoptosis. The effect of protein S on diabetes and its complications is unknown. This study compared the development of diabetes between wild-type and transgenic mice over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4562c2380d155c89eebff4bf5a82f007
https://doi.org/10.2337/db15-1404
https://doi.org/10.2337/db15-1404
Autor:
Masaaki Toda, Rumi Mifuji-Moroka, Yoshiyuki Takei, Corina N. D' Alessandro-Gabazza, Kota Nishihama, Tetsu Kobayashi, Esteban C. Gabazza, Yutaka Yano, Prince Baffour Tonto, Motoh Iwasa, Toshiaki Totoki, Atsuro Takeshita, Taro Yasuma, Isaac Cann, John Morser, Josephine A. Hinneh
Publikováno v:
Metabolism: clinical and experimental. 82
Background Chronic progression of diabetes is associated with decreased pancreatic islet mass due to apoptosis of β-cells. Patients with diabetes have increased circulating matrix metalloproteinase-2 (MMP2); however, the physiological significance h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900b569ce968029834089401954d8705
https://pubmed.ncbi.nlm.nih.gov/29366755
https://pubmed.ncbi.nlm.nih.gov/29366755
Autor:
Esteban C. Gabazza, Osamu Taguchi, Masahiro Kajiki, Hajime Fujimoto, Yoshiyuki Takei, Masaaki Toda, Hiroki Nakahara, Kentaro Fujiwara, Yoshinori Takahashi, Kota Nishihama, Tetsu Kobayashi, Josephine A. Hinneh, Taro Yasuma, Corina N. D’Alessandro-Gabazza
Publikováno v:
The American journal of pathology. 187(10)
Pulmonary fibrosis is the terminal stage of a group of idiopathic interstitial pneumonias, of which idiopathic pulmonary fibrosis is the most frequent and fatal form. Recent studies have shown that recombinant human thrombomodulin (rhTM) improves exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219f54668a0001fb88166e107c6e86ea
https://pubmed.ncbi.nlm.nih.gov/28739343
https://pubmed.ncbi.nlm.nih.gov/28739343
Autor:
Masaaki Toda, Tetsu Kobayashi, Ziauraman Roeen, Taro Yasuma, Osamu Taguchi, Yoshiyuki Takei, Corina N. D’Alessandro-Gabazza, Esteban C. Gabazza, Hajime Fujimoto, Masahito Urawa, Josephine A. Hinneh
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 14(8)
Essentials Epithelial cell apoptosis is critical in the pathogenesis of idiopathic pulmonary fibrosis. Protein S, a circulating anticoagulant, inhibited apoptosis of lung epithelial cells. Overexpression of protein S in lung cells reduced bleomycin-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a22e3252319d4eddc19135a478f7943
https://pubmed.ncbi.nlm.nih.gov/27172994
https://pubmed.ncbi.nlm.nih.gov/27172994