Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joseph Z, Zaretsky"'
Mucins are glycoproteins that are expressed in cells of different types and fulfill multiple functions that determine participation of these proteins in such processes as signal transduction, regulation of gene expression, cell proliferation, embryog
Autor:
Joseph Z. Zaretsky, Michael A. McGuckin, Pavlos Neophytou, His-Hsien Lin, Merav Yoeli, Iafa Keydar, Stefanie J. Williams, Ravit Ziv, Amos Baruch, Daniel H. Wreschner, Martin Stacey, Nechama I. Smorodinsky, Siamon Gordon, Liron Okun
Publikováno v:
Protein Science. 11:698-706
A mechanism is described whereby one and the same gene can encode both a receptor protein as well as its specific ligand. Generation of this receptor-ligand partnership is effected by proteolytic cleavage within a specific module located in a membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1173b966f115e58d6cb0d27e9455be
https://doi.org/10.1110/ps.16502
https://doi.org/10.1110/ps.16502
Publikováno v:
Translational Oncogenomics
In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7432daa5c0fd9813336f6855e05905f
http://europepmc.org/articles/PMC3022353
http://europepmc.org/articles/PMC3022353
Autor:
Cornelius F. Boerkoel, Joseph Z. Zaretsky, Fabio Candotti, Elizabeth Adams, Jonathan W. Yewdell, R. Michael Blaese, Paul H. Plotz
Publikováno v:
Human Gene Therapy. 8:1555-1563
Myoblasts have properties that make them suitable vehicles for gene replacement therapy, and lysosomal storage diseases are attractive targets for such therapy. Type II Glycogen Storage Disease, a deficiency of acid alpha-glucosidase (GAA), results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee51d2c29bd1c3725d82f9a095e15ee
https://doi.org/10.1089/hum.1997.8.13-1555
https://doi.org/10.1089/hum.1997.8.13-1555
Publikováno v:
Series Title: Mucins – Potential Regulators of Cell Functions Volume Title: Gel-Forming and Soluble Mucins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11c3587589a656515e5ad024da503fd8
https://doi.org/10.2174/97816080545411130101
https://doi.org/10.2174/97816080545411130101
Autor:
Daniel H. Wreschner, Joseph Z. Zaretsky, A.S. Dion, R. Zimlichman, Iafa Keydar, Nechama I. Smorodinsky, Mordechai Weiss
Publikováno v:
Cancer Letters. 58:125-130
The expression of the H23 gene, previously shown to be overexpressed in breast cancer tissue, was examined in various thyroid pathologies. Thyroid papillary carcinomas demonstrate significant H23 mRNA levels, whereas benign thyroid pathologies have v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8065403d9656ece35495efea6b05d8a0
https://doi.org/10.1016/0304-3835(91)90034-f
https://doi.org/10.1016/0304-3835(91)90034-f
Autor:
Joseph Z, Zaretsky, Itay, Barnea, Yael, Aylon, Marat, Gorivodsky, Daniel H, Wreschner, Iafa, Keydar
Publikováno v:
Molecular Cancer
Background The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors its transcription is dramatically upregulated. Of particular relevance to breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9182e464d0deb2a196046da35d816388
https://pubmed.ncbi.nlm.nih.gov/17083744
https://pubmed.ncbi.nlm.nih.gov/17083744
Autor:
Moshe Simha, Yona Stadler, Merav Yoeli-Lerner, Ravit Ziv, Mordechai Weiss, Alina Cholostoy, Mor-li Hartmann, Sheila Zrihan-Licht, Sima Shina, Beatrice Lifschitz, Joseph Z. Zaretsky, Fiana Levitin, Iafa Keydar, Keren Stiegman, Daniel H. Wreschner, Benny Gil, Amos Baruch, Andrea Gat, David R. Greaves, Nechama I. Smorodinsky
Publikováno v:
The Journal of biological chemistry. 280(11)
Genes that have been designated the name "MUC" code for proteins comprising mucin domains. These proteins may be involved in barrier and protective functions. The first such gene to be characterized and sequenced is the MUC1 gene. Here we report a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eda7a3575c64545f0c1a739fac2a700
https://pubmed.ncbi.nlm.nih.gov/15623537
https://pubmed.ncbi.nlm.nih.gov/15623537
Autor:
Mordechai Weiss, A.S. Dion, Daniel H. Wreschner, Nechama I. Smorodinsky, Ilan Tsarfaty, Iafa Keydar, Phillip Kotkes, Mara Hareuveni, Charlene J. Williams, Judith Horev, Joseph Z. Zaretsky, K. McCarthy, S. Zrihan, M. Burstein, Richard Lathe, C. A. Hart
Publikováno v:
Breast Epithelial Antigens ISBN: 9781461366652
The isolation and characterization of the complementary DNAs (cDNAs) and gene which code for an epithelial tumor antigen (H23-ETA), aberrantly expressed in human breast tumor tissue, are described here. A diversity of H23-ETA protein forms, is genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e051d82375dd9fed3f3e43aee4f63443
https://doi.org/10.1007/978-1-4615-3740-3_1
https://doi.org/10.1007/978-1-4615-3740-3_1
Autor:
Mordechai Weiss, Iafa Keydar, Daniel H. Wreschner, Ilan Tsarfaty, Joseph Z. Zaretsky, Mara Hareuveni, Jean-Marie Garnier, Richard Lathe, Judith Horev, J.M Jeitsch
Publikováno v:
Gene. 93(2)
A human gene and cDNA coding for a breast-cancer-associated antigen (H23Ag) were isolated and characterized. The gene contains two exons and one intron. Part of the second exon is a tandem repeat array (TRA) consisting of multiple 60-bp G + C-rich un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12e3e3276f79abd21e39d539f72c4ac
https://pubmed.ncbi.nlm.nih.gov/1688329
https://pubmed.ncbi.nlm.nih.gov/1688329