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pro vyhledávání: '"Joseph Wieczorek"'
Autor:
John P. Adamek, Kevin A. Babiak, Medich John R, James R. Behling, John S. Ng, Joseph Wieczorek, John H. Dygos
Publikováno v:
The Journal of Organic Chemistry. 56:2549-2552
An efficient 11-step synthesis of the antisecretory prostaglandin enisoprost starting with (Z,Z)-1,5-cyclooctadiene has been developed. The key steps in the synthesis are a selective ozonolysis of (Z,Z)-1,5-cyclooctadiene, a zinc chloride catalyzed r
Publikováno v:
Journal of the American Chemical Society. 86:742-743