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pro vyhledávání: '"Joseph Wendell Wilson"'
Autor:
Anthony L. Handlon, Lisa M. Leesnitzer, Joseph Wendell Wilson, Rodolfo Cadilla, Philip Stewart Turnbull, Chuck Poole, Raymond V. Merrihew, Lee T. Schaller, John C. Ulrich
Publikováno v:
ACS Medicinal Chemistry Letters. 7:83-88
A series of selective androgen receptor modulators (SARMs) containing the 1-(trifluoromethyl)benzyl alcohol core have been optimized for androgen receptor (AR) potency and drug-like properties. We have taken advantage of the lipophilic ligand efficie