Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joseph W. Oakes"'
Publikováno v:
Human Gene Therapy. 5:1315-1324
A variety of genetic therapies or intracellular immunization techniques hold promise as modalities to inhibit human immunodeficiency virus type 1 (HIV-1) replication in vivo. We have recently demonstrated that a single-chain variable fragment (SFv) c
Publikováno v:
AIDS Research and Human Retroviruses. 10:1213-1219
Human immunodeficiency virus type 1 (HIV-1) replication is controlled by a complex array of virally encoded and cellular proteins. A wide spectrum of levels of HIV-1 expression have been demonstrated in various cells, both in cell culture and in vivo
Publikováno v:
Journal of Virology. 68:4302-4313
The p53 tumor suppressor gene product, a sequence-specific DNA-binding protein, has been shown to act as a transcriptional activator and repressor both in vitro and in vivo. Consistent with its role in regulating transcription are recent observations
Publikováno v:
Journal of Virological Methods. 40:331-345
The ability to evaluate the patterns and levels of human immunodeficiency virus type I (HIV-1)-specific RNA in latently and productively-infected cell lines, and primary human cells, is critical to the understanding of HIV-1 expression in cell cultur
Autor:
Thikkavarapu Seshamma, Omar Bagasra, Homayoon Farzadegan, Joseph W. Oakes, Alfred J. Saah, Roger J. Pomerantz
Publikováno v:
AIDS (London, England). 8(12)
Sexual transmission is a major mode of the spread of HIV-1, although the cellular and molecular mechanisms are poorly defined. In this study, we sought to assess the cellular reservoirs of HIV-1 proviral DNA in the semen of HIV-1-infected men.An in s
Human immunodeficiency virus type 1 (HIV-1) has a complex life cycle, which has made it a difficult target for conventional therapeutic modalities. A single-chain antibody moiety, directed against the HIV-1 regulatory protein Rev, which rescues unspl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4319ab88ca3183a61d84503195168727
https://europepmc.org/articles/PMC43934/
https://europepmc.org/articles/PMC43934/
Publikováno v:
Virology. 199(2)
Human immunodeficiency virus type 1 (HIV-1) can infect various cell lines in culture and be maintained in a chronic state of restricted replication. These states of proviral latency are characterized by a predominance of spliced compared to unspliced
Publikováno v:
AIDS (London, England). 7
HIV-1 infection of humans causes immunosuppression. The determination of precise levels of HIV-1 infection of cells in vivo may assist in the understanding of the pathogenetic processes involved in clinical infection with this virus. Studies using po
Publikováno v:
AIDS (London, England). 7(11)
HIV-1 infection of humans leads to states of immunosuppression. Therefore, we sought to determine precise levels of HIV-1 infection of cells in vivo, as these data may assist in the understanding of the pathogenetic processes involved in HIV infectio
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(14)
Lipopolysaccharide (LPS) potently stimulates human immunodeficiency virus type 1 (HIV-1) long terminal repeat-directed transcription in transfected monocyte-macrophage cell lines and dramatically increases HIV-1 production in the latently infected mo