Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Joseph W Gordon"'
Autor:
Evan Stefanek, Ehsan Samiei, Mahboubeh Kavoosi, Mohammad Esmaeillou, Kiarash Roustai Geraylow, Arya Emami, Milad Ashrafizadeh, David Perrin, Joseph W Gordon, Mohsen Akbari, Saeid Ghavami
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101473- (2021)
Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue malignant tumor. Treatment of RMS usually includes primary tumor resection along with systemic chemotherapy. Two-dimensional (2D) cell culture systems and animal models have been extensi
Externí odkaz:
https://doaj.org/article/8edef28227ad4655b5831f203c6c07a3
Autor:
Bhavya Bhushan, Rosa Iranpour, Amirmohammad Eshtiaghi, Simone C. da Silva Rosa, Benjamin W. Lindsey, Joseph W. Gordon, Saeid Ghavami
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2791 (2024)
Alveolar rhabdomyosarcoma (ARMS), an invasive subtype of rhabdomyosarcoma (RMS), is associated with chromosomal translocation events resulting in one of two oncogenic fusion genes, PAX3-FOXO1 or PAX7-FOXO1. ARMS patients exhibit an overexpression of
Externí odkaz:
https://doaj.org/article/2a37e27a1ae147c981b1a9fbb57fdc47
Autor:
Ali Zarrabi, David Perrin, Mahboubeh Kavoosi, Micah Sommer, Serap Sezen, Parvaneh Mehrbod, Bhavya Bhushan, Filip Machaj, Jakub Rosik, Philip Kawalec, Saba Afifi, Seyed Mohammadreza Bolandi, Peiman Koleini, Mohsen Taheri, Tayyebeh Madrakian, Marek J. Łos, Benjamin Lindsey, Nilufer Cakir, Atefeh Zarepour, Kiavash Hushmandi, Ali Fallah, Bahattin Koc, Arezoo Khosravi, Mazaher Ahmadi, Susan Logue, Gorka Orive, Stevan Pecic, Joseph W. Gordon, Saeid Ghavami
Publikováno v:
Cancers, Vol 15, Iss 21, p 5269 (2023)
Rhabdomyosarcoma is a rare cancer arising in skeletal muscle that typically impacts children and young adults. It is a worldwide challenge in child health as treatment outcomes for metastatic and recurrent disease still pose a major concern for both
Externí odkaz:
https://doaj.org/article/1879e2d72f5642c88599f2dbc9136ec7
Publikováno v:
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Abstract Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an imperative need for research into insulin resistance to bet
Externí odkaz:
https://doaj.org/article/c819aac9017e40b28a5fb6fa2a052ea7
Publikováno v:
International Journal of Basic Science in Medicine, Vol 2, Iss 1, Pp 1-4 (2017)
Rhabdomyosarcoma (RMS) is a muscle-derived tumor and is the most common pediatric soft tissue sarcoma representing 5% of all childhood cancers. Statistically, soft tissue sarcomas account for approximately 10% of all cancers in children, of which mor
Externí odkaz:
https://doaj.org/article/17fc838f4b53467eb2cffef1677d0d6f
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 320:H2169-H2184
The small lipid-derived paracrine signaling molecules known as prostaglandins have been recognized for their ability to modulate many facets of cardiovascular physiology since their initial discovery more than 85 years ago. Although the role of prost
Autor:
Vernon W. Dolinsky, Simone C. da Silva Rosa, Saeid Ghavami, Christof Rampitsch, Lucas Nguyen, James A. Thliveris, Matthew D. Martens, Donald Chapman, Joseph W. Gordon, Adrian R. West, Stephanie M. Kereliuk, Yan Hai, Jared T. Field, William Diehl-Jones, Michel Aliani
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Lipotoxicity is a form of cellular stress caused by the accumulation of lipids resulting in mitochondrial dysfunction and insulin resistance in muscle. Previously, we demonstrated that the mitophagy receptor BNIP3L/Nix is responsive to lipotoxicity a
Autor:
Philip Kawalec, Matthew D. Martens, Jared T. Field, Wajihah Mughal, Andrei Miguel Caymo, Donald Chapman, Bo Xiang, Saeid Ghavami, Vernon W. Dolinsky, Joseph W. Gordon
Publikováno v:
Toxicology and applied pharmacology. 453
Doxorubicin (DOX) is an effective anthracycline used in chemotherapeutic regimens for a variety of haematological and solid tumors. However, its utility remains limited by its well-described, but poorly understood cardiotoxicity. Despite numerous stu
Autor:
Patience O. Obi, Samira Seif, Benjamin Bydak, Taiana M. Pierdoná, Emily Turner-Brannen, Adrian R. West, Hagar I. Labouta, Joseph W. Gordon, Ayesha Saleem
Extracellular vesicles (EVs) are small lipid membrane-bound structures that are secreted by all cells, and play a central role in cellular communication. EVs are released from skeletal muscle during exercise, but the effects of contractile activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a555ebfa7d9cf74c1a49675608170080
https://doi.org/10.1101/2022.02.25.481852
https://doi.org/10.1101/2022.02.25.481852
Autor:
Benjamin Bydak, Taiana M. Pierdoná, Samira Seif, Karim Sidhom, Patience O. Obi, Hagar I. Labouta, Joseph W. Gordon, Ayesha Saleem
Extracellular vesicles (EVs) released from all cells, are essential to cellular communication, and contain biomolecular cargo that can affect recipient cell function. Studies on the effects of contractile activity (exercise) on EVs usually rely on pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2781aa171b4ac152004523790a7fc0
https://doi.org/10.1101/2022.02.20.481208
https://doi.org/10.1101/2022.02.20.481208