Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joseph Visone"'
Autor:
Hyomin Kim, David Witten, Julius Madey, Nathaniel Frissell, John Gibbons, William Engelke, Anderson Liddle, Nicholas Muscolino, Joseph Visone, Zhaoshu Cao
Publikováno v:
HardwareX, Vol 20, Iss , Pp e00580- (2024)
As part of Ham Radio Science Citizen Investigation (HamSCI) Personal Space Weather Station (PSWS) project, a low-cost, commercial off-the-shelf magnetometer has been developed to provide quantitative and qualitative measurements of the geospace envir
Externí odkaz:
https://doaj.org/article/86429ed762f74b3da570728078bbac83
Autor:
John Ginn, Wenhu Zhan, Gang Lin, Roland A. Cooper, Philip J. Rosenthal, Rong Wang, Tzu-Tshin Wong, Patrick K Tumwebaze, Joseph Visone, Laura A. Kirkman, George Sukenick, Björn F.C. Kafsack, Judith I. Okoro, Pradeep K. Singh, Hao Zhang, Ryan M. Scales, Jacob C. Harris, Peter T. Meinke, Tierra Ouellette
Publikováno v:
Journal of Medicinal Chemistry. 62:6137-6145
The Plasmodium proteasome (Pf20S) emerged as a target for antimalarials. Pf20S inhibitors are active at multiple stages of the parasite life cycle and synergize with artemisinins, suggesting that Pf20S inhibitors have potential to be prophylactic, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b752f3425aaccf03ce69b394fbb7432
https://doi.org/10.1021/acs.jmedchem.9b00363
https://doi.org/10.1021/acs.jmedchem.9b00363
Autor:
Matthew S. Simon, Stephen G. Jenkins, Laura A. Kirkman, Audrey N. Schuetz, Lars F. Westblade, Richard R. Furman, Joseph Visone, Alexis Dziedziech
Publikováno v:
Clinical Infectious Diseases. 65:1222-1225
Babesiosis treatment failures with standard therapy have been reported, but the molecular mechanisms are not well understood. We describe the emergence of atovaquone and azithromycin resistance associated with mutations in the binding regions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2bbeabb90f2113775e13b1ea186aa5
https://doi.org/10.1093/cid/cix477
https://doi.org/10.1093/cid/cix477
Autor:
Jeremie Vendome, Yan Ling, Roland A. Cooper, Pradeep K. Singh, Liselle F. Guiang, Elena Fernández Álvaro, Kazuyoshi Aso, Laura A. Kirkman, Björn F.C. Kafsack, Carl Nathan, Lei Shi, Rong Wang, Joseph Visone, Purnima Bhanot, Patrick K Tumwebaze, Masanori Kawasaki, Ryoma Hara, Kavitha Govindasamy, Alexis Dziedziech, George Sukenick, Hao Fan, Mayako Michino, Rei Okamoto, J. Stone Doggett, Philip J. Rosenthal, Xinran Tong, Igor Bruzual, Kenjiro Sato, Michael Foley, Toshihiro Imaeda, Laura M. Sanz, Daniel Mota, Wenhu Zhan, Gang Lin
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Proceedings of the National Academy of Sciences of the United States of America
Consejería de Sanidad de la Comunidad de Madrid
Proceedings of the National Academy of Sciences of the United States of America
Significance Protozoal proteasome is a validated target for antimalarial drug development, but species selectivity of reported inhibitors is suboptimal. Here we identify inhibitors with improved selectivity for malaria proteasome β5 subunit over eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efed7ad5f1e219e76055aed62b5b9cde
https://doi.org/10.1073/pnas.1806109115
https://doi.org/10.1073/pnas.1806109115