Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joseph V. Ordas"'
Autor:
Patton E. Garay, Ester Fernandez-Salas, Marcella A. Gilmore, Helen Ho, Sarah W. Sun, K. Roger Aoki, Lance E. Steward, Joanne Wang, Joseph V. Ordas, Joseph Francis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(9)
Botulinum neurotoxin (BoNT) is a potent biological substance used to treat neuromuscular and pain disorders. Both BoNT type A and BoNT type E display high-affinity uptake into motor neurons and inhibit exocytosis through cleavage of the synaptosome-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db49774b2459ebce2c35aa72b88d1c5f
https://pubmed.ncbi.nlm.nih.gov/14982988
https://pubmed.ncbi.nlm.nih.gov/14982988
Autor:
Nicholson Gregory, Fernandez-Salas Ester, Brown Meenakshi, Okawa Yumiko, Francis Joseph, Sun Sarah, Lance E. Steward, K. Roger Aoki, Hieu T. Arpawong, Satorius Alan, Maria C. Ardila, Joseph V. Ordas, Wang Joanne, Marcella A. Gilmore
Publikováno v:
Toxicon. 51:11-12
Both rHis6-BoNT/E and rBoNT/E-His6 were produced from a codon optimized gene within Escherichia coli. Similar to native BoNT/E isolated from Clostridium botulinum, the recombinant proteins were isolated as single-chain molecules. The His6 affinity ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92c3f7ae12ec5aa58d9c412497746cf
https://doi.org/10.1016/j.toxicon.2008.04.035
https://doi.org/10.1016/j.toxicon.2008.04.035