Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Joseph U Igietseme"'
Autor:
Roshan Pais, Yusuf Omosun, Qing He, Uriel Blas-Machado, Carolyn Black, Joseph U Igietseme, Kohtaro Fujihashi, Francis O Eko
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178537 (2017)
In this study, we tested the hypothesis that rectal immunization with a VCG-based chlamydial vaccine would cross-protect mice against heterologous genital Chlamydia trachomatis infection and Chlamydia-induced upper genital tract pathologies in mice.
Externí odkaz:
https://doaj.org/article/9de309a6406f434ba0ccdbbd94408e07
Autor:
Danielle N McKeithen, Yusuf O Omosun, Khamia Ryans, Jing Mu, Zhonglin Xie, Tankya Simoneaux, Uriel Blas-Machado, Francis O Eko, Carolyn M Black, Joseph U Igietseme, Qing He
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188643 (2017)
Chlamydia trachomatis is a bacterial agent that causes sexually transmitted infections worldwide. The regulatory functions of dendritic cells (DCs) play a major role in protective immunity against Chlamydia infections. Here, we investigated the role
Externí odkaz:
https://doaj.org/article/3f87d0d3d6704aa0b36aa165f6e51812
Autor:
Joseph U Igietseme, Yusuf Omosun, Olga Stuchlik, Matthew S Reed, James Partin, Qing He, Kahaliah Joseph, Debra Ellerson, Brigid Bollweg, Zenas George, Francis O Eko, Claudiu Bandea, Hsi Liu, Genyan Yang, Wun-Ju Shieh, Jan Pohl, Kevin Karem, Carolyn M Black
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145198 (2015)
Chlamydia trachomatis genital infection in women causes serious adverse reproductive complications, and is a strong co-factor for human papilloma virus (HPV)-associated cervical epithelial carcinoma. We tested the hypothesis that Chlamydia induces ep
Externí odkaz:
https://doaj.org/article/e3584235c01b41b3af7b6437f572c67d
Autor:
Shanshan Liu, Wei Sun, Jun Chu, Xiufen Huang, Zongxue Wu, Minxin Yan, Qiang Zhang, Peng Zhao, Joseph U Igietseme, Carolyn M Black, Cheng He, Yongqing Li
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124992 (2015)
Chlamydia psittaci (C. psittaci) is an obligate intracellular zoonotic pathogen that can be transmitted to humans from birds. No efficacious commercial vaccine is available for clearing chlamydial infection due to lack of potential vaccine candidates
Externí odkaz:
https://doaj.org/article/d2f63f36f421454885d0ed8cef67bbcd
Publikováno v:
African Journal of Laboratory Medicine, Volume: 12, Issue: 1, Pages: 1-10, Published: 2023
A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in China in 2019 and later ignited a global pandemic. Contrary to expectations, the effect of the pandemic was not as devastating to Africa a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5804dc206818849d92382e81bd0ac3b1
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S2225-20102023000100004&lng=en&tlng=en
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S2225-20102023000100004&lng=en&tlng=en
Autor:
Debra Ellerson, Sunny Onyeabor, Jason P. DeBruyne, Francis O. Eko, Joseph U. Igietseme, Alec J. Davidson, Shakyra Richardson, Carolyn M. Black, Yusuf Omosun, Winston E. Thompson, Qing He, Stephanie R. Lundy, Anne Ramsey, Ward Kirlin, Lilly Cheng Immergluck, Uriel Blas-Machado, Yan Fengxia
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Shift work, performed by approximately 21 million Americans, is irregular or unusual work schedule hours occurring after 6:00 pm. Shift work has been shown to disrupt circadian rhythms and is associated with several adverse health outcomes and chroni
Autor:
Darin S. Carroll, Stephanie R. Lundy, Shakyra Richardson, Fnu Medhavi, Joseph U. Igietseme, Yusuf Omosun, Tayhlor Tanner, Francis O. Eko
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Efficacious vaccines are needed to control genital chlamydial diseases in humans and the veterinary industry. We previously reported a C. abortus (Cab) vaccine comprising recombinant Vibrio cholerae ghosts (rVCG) expressing the conserved and immunoge
Autor:
Ifeyinwa Benyeogor, Carolyn M. Black, YeMaya Robinson, Yusuf Omosun, Tolulope Omosun, Ward Kirlin, Francis O. Eko, Tarek A. Ahmad, Uriel Blas-Machado, Tankya Simoneaux, Qing He, Stephanie R. Lundy, Jason P. DeBruyne, Debra Ellerson, Joseph U. Igietseme, Zenas George
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Genital chlamydia infection in women causes complications such as pelvic inflammatory disease and tubal factor infertility, but it is unclear why some women are more susceptible than others. Possible factors, such as time of day of chlamydia infectio
Autor:
Claudiu I. Bandea, Yusuf Omosun, Olga Stuchlik, Kahaliah Joseph, Zenas George, Carolyn M. Black, Joseph U. Igietseme, Jason M. Goldstein, Anthony A. Azenabor, Matthew S. Reed, James Partin, Francis O. Eko, Pavel Svoboda, Debra Ellerson, Jan Pohl, Qing He, Erika I. Lutter, Melissa A. McDonald
Publikováno v:
Biochemical and Biophysical Research Communications. 508:421-429
The unfolded protein response (UPR) contributes to chlamydial pathogenesis, as a source of lipids and ATP during replication, and for establishing the initial anti-apoptotic state of host cell that ensures successful inclusion development. The molecu
Autor:
Francis O. Eko, Joseph U. Igietseme, Yusuf Omosun, Kobe Abney, Debra Ellerson, Stephanie R. Lundy, Darin S. Carroll
Publikováno v:
Pathogens, Vol 10, Iss 566, p 566 (2021)
Pathogens
Volume 10
Issue 5
Pathogens
Volume 10
Issue 5
Genital Chlamydia trachomatis infection causes severe reproductive pathologies such as salpingitis and pelvic inflammatory disease that can lead to tubal factor infertility. MicroRNAs (miRNAs) are evolutionarily conserved regulators of mammalian gene