Výsledky vyhledávání - "Joseph Tandurella"

Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin

Autor: Eloïse M. Grasset, Matthew Dunworth, Gaurav Sharma, Melanie Loth, Joseph Tandurella, Ashley Cimino-Mathews, Melissa Gentz, Sydney Bracht, Meagan Haynes, Elana J. Fertig, Andrew J. Ewald

Publikováno v: Sci Transl Med

Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early metastatic recurrence and worse patient outcomes. TNBC tumors express molecular markers of the epithelial-mesenchymal transition (EMT), but its requirement during spo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97180667182407f660f11162c05473b
https://doi.org/10.1126/scitranslmed.abn7571

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Abstract 5851: Cancer associated fibroblast crosstalk through VEGF increases tumor cell proliferation in human pancreatic ductal adenocarcinoma

Autor: Samantha Guinn, Joseph Tandurella, Jignasha Patel, Richard Burkhart, Jacquelyn Zimmerman, Elizabeth Jaffee

Publikováno v: Cancer Research. 83:5851-5851

Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a classically heterogeneous tumor for which tumor cells comprise less than 40% of the total tumor mass. To better understand mechanisms of intercellular interactions driving tumor response or r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::501701cf874391a947af78f640d85681
https://doi.org/10.1158/1538-7445.am2023-5851

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Abstract C036: Cancer associated fibroblasts are regulators of the tumor microenvironment in human pancreatic ductal adenocarcinoma

Autor: Samantha Guinn, Joseph Tandurella, Jacquelyn Zimmerman, Richard Burkhart, Elizabeth M. Jaffee

Publikováno v: Cancer Research. 82:C036-C036

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d67ff80e2003cbdd6a4244d231bef692
https://doi.org/10.1158/1538-7445.panca22-c036

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Abstract 1480: miR-21 as a post-transcriptional regulator of pancreatic ductal adenocarcinoma (PDAC) tumorigenesis

Autor: Jacquelyn W. Zimmerman, Daniel H. Shu, Richard A. Burkhart, Joseph Tandurella, Elana J. Fertig, Elizabeth M. Jaffee

Publikováno v: Cancer Research. 82:1480-1480

Introduction: MicroRNAs are short non-coding RNAs that are frequently dysregulated across cancers. Specifically, microRNA-21 (miR-21) is a known oncomir overexpressed in pancreatic adenocarcinoma (PDAC) that regulates multiple gene targets downstream

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85d8a6ad1641b5bdc77a56e49f52fbd3
https://doi.org/10.1158/1538-7445.am2022-1480

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