Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joseph T. Paletta"'
Autor:
Hung V.-T. Nguyen, Qixian Chen, Joseph T. Paletta, Peter Harvey, Yivan Jiang, Hui Zhang, Michael D. Boska, M. Francesca Ottaviani, Alan Jasanoff, Andrzej Rajca, Jeremiah A. Johnson
Publikováno v:
ACS Central Science, Vol 3, Iss 7, Pp 800-811 (2017)
Externí odkaz:
https://doaj.org/article/079b8a4a6a604155aae95e459ec05f4b
Publikováno v:
Free Radical Research. 52:327-334
Tetracarboxylate pyrroline nitroxides undergo very fast reduction with ascorbate/glutathione (GSH), with second-order rate constants that are five orders of magnitude greater than those for gem-diethyl pyrroline nitroxides. For tetracarboxylate nitro
Autor:
Jeremiah A. Johnson, M. Francesca Ottaviani, Hui Zhang, Joseph T. Paletta, Andrzej Rajca, Peter Harvey, Alan Jasanoff, Qixian Chen, Michael D. Boska, Yivan Jiang, Hung V.-T. Nguyen
Publikováno v:
ACS Central Science
ACS Central Science, Vol 3, Iss 7, Pp 800-811 (2017)
ACS Central Science, Vol 3, Iss 7, Pp 800-811 (2017)
Metal-free magnetic resonance imaging (MRI) agents could overcome the established toxicity associated with metal-based agents in some patient populations and enable new modes of functional MRI in vivo. Herein, we report nitroxide-functionalized brush
Autor:
Sandra S. Eaton, Maren Pink, Hanan Elajaili, Gareth R. Eaton, Shengdian Huang, Andrzej Rajca, Joseph T. Paletta, Kirby Huber, Suchada Rajca
Publikováno v:
The Journal of Organic Chemistry
We report the design, synthesis, and electron spin relaxation properties of hydrophilic tetracarboxylate ester pyrroline nitroxides 1 and 2, which serve as models in the search for new spin labels for DEER distance measurement at room temperature. Th
Publikováno v:
Organic Letters. 14:5322-5325
A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e.,
Autor:
Joseph T. Paletta, Suchada Rajca, Erin F. Reinhart, Ying Wang, Andrzej Rajca, Kathleen E. Berg
Publikováno v:
Organic Letters
A series of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides were synthesized. Their reduction by ascorbate/glutathione indicates that l-cysteine functionalized with gem-diethylpyrroline nitroxide is reduced at the s
Autor:
Ying Wang, Jessica R. McCombs, Paula T. Hammond, Erik C. Dreaden, Stephen W. Morton, Michael D. Boska, Jeremiah A. Johnson, M. Francesca Ottaviani, Andrzej Rajca, Molly A. Sowers, Joseph T. Paletta
Publikováno v:
PMC
Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics. Herein, we report the development of a new class of branched-bottlebrush polymer dual-modality organic radical contrast agents—ORCAFluors—for combined ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b70ff726668ce7a8fcf12272c062ed
https://hdl.handle.net/11576/2618410
https://hdl.handle.net/11576/2618410
Autor:
Christie L. Beck, Alexander T. Buck, Arthur H. Winter, Shalika A. Khindurangala, Joseph T. Paletta
Publikováno v:
Journal of the American Chemical Society. 135(29)
We report an organo-paramagnetic switch consisting of a linked bis(viologen) dication diradical that can be cycled reversibly between diamagnetic and paramagnetic states via noncovalent guest–host chemistry with cucurbit[7]uril (CB[7]) in room-temp
Autor:
Sandra S. Eaton, Deborah G. Mitchell, Gareth R. Eaton, Andrzej Rajca, Michael A. Swanson, Ying Wang, Arnon Olankitwanit, Suchada Rajca, Michael D. Boska, Joseph T. Paletta
We report a molecular design that provides an intravenously injectable organic radical contrast agent (ORCA) for which the molecular 1H water relaxivity (r1) is ca. 5 mM–1 s–1. The ORCA is based on spirocyclohexyl nitroxide radicals and poly(ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f586ad1b158dae40d634247618d1f78
https://europepmc.org/articles/PMC3486519/
https://europepmc.org/articles/PMC3486519/
Autor:
Ying Wang, Suchada Rajca, Arnon Olankitwanit, Joseph T. Paletta, Deborah G. Mitchell, Andrzej Rajca, Michael A. Swanson, Michael D. Boska, Gareth R. Eaton, Sandra S. Eaton
Publikováno v:
Journal of the American Chemical Society. 136:3318-3318
We re-examined the T1 weighted raw data and found that the raw signal intensity scale was changing despite the designation of “absolute value” reconstruction on the Bruker scanner. There was a hidden “slope” factor that modifies the raw inten