Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Joseph T. Nickels"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/7cffb206fbb54fd6b45758e493ca4209
Autor:
Michelle L Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T Nickels
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235746 (2020)
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therap
Externí odkaz:
https://doaj.org/article/69957f3095894e4e9a1f75421cbf0efb
Autor:
Joseph T. Nickels, Jr.
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 919-921 (2019)
Externí odkaz:
https://doaj.org/article/315306750c4a457cb07f8286a0cc721c
Autor:
Paula McCourt, Hsing-Yin Liu, Josie E. Parker, Christina Gallo-Ebert, Melissa Donigan, Adam Bata, Caroline Giordano, Steven L. Kelly, Joseph T. Nickels Jr
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 11, Pp 3455-3465 (2016)
Candida albicans is an opportunistic fungus responsible for the majority of systemic fungal infections. Multiple factors contribute to C. albicans pathogenicity. C. albicans strains lacking CaArv1 are avirulent. Arv1 has a conserved Arv1 homology dom
Externí odkaz:
https://doaj.org/article/a15f8b76876e493988f69f9025cdca27
Autor:
Muhua Yang, Joseph T. Nickels
Publikováno v:
Diseases, Vol 3, Iss 3, Pp 176-192 (2015)
Metabolic syndrome is an ever-increasing health problem among the world’s population. It is a group of intertwined maladies that includes obesity, hypertriglyceridemia, hypertension, nonalcoholic fatty liver disease (NAFLD), and diabetes mellitus t
Externí odkaz:
https://doaj.org/article/e0bfb562ed09420da924c6f8624b8e36
Autor:
Muhua Yang, Weidong Liu, Christina Pellicane, Christine Sahyoun, Biny K. Joseph, Christina Gallo-Ebert, Melissa Donigan, Devanshi Pandya, Caroline Giordano, Adam Bata, Joseph T. Nickels, Jr.
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 2, Pp 226-238 (2014)
Dysregulation of cholesterol homeostasis is associated with various metabolic diseases, including atherosclerosis and type 2 diabetes. The sterol response element binding protein (SREBP)-2 transcription factor induces the expression of genes involved
Externí odkaz:
https://doaj.org/article/e8ec46e393164b3f89563e1d830de6fa
Autor:
Raymond G. Franks, Dividutta Das, Alyssa M. Brown, Michael Hayward, Joseph T. Nickels, Jessie Lee Cunningham, Karla K. Frietze
Publikováno v:
Autophagy
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease globally. NAFLD is a consequence of fat accumulation in the liver leading to lipotoxicity. Increasing evidence has demonstrated the critical role of autophagy in N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d2934fe907298698b05282eeccd841
https://doi.org/10.1080/15548627.2021.1920818
https://doi.org/10.1080/15548627.2021.1920818
Autor:
Karla K. Frietze, Michael Hayward, Weidong Liu, Jessie Lee Cunningham, Joshua Wayne, Alyssa D. Brown, Joseph T. Nickels
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884b90aff544dbb9881012c9887441bb
https://doi.org/10.1096/fasebj.2021.35.s1.05274
https://doi.org/10.1096/fasebj.2021.35.s1.05274
Autor:
Virginia McDonough, Muhua Yang, Joseph T. Nickels, Christina Gallo-Ebert, Michael Hayward, Weidong Liu
Publikováno v:
Molecular and Cellular Biology. 40
Genome-wide association studies (GWAS) have linked IGF2BP2 single-nucleotide polymorphisms (SNPs) with type 2 diabetes (T2D). Mice overexpressing mIGF2BP2 have elevated cholesterol levels when fed a diet that induces hepatic steatosis. These and othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64556d0ce7b2632927e08f70936dfeb3
https://doi.org/10.1128/mcb.00058-20
https://doi.org/10.1128/mcb.00058-20
Autor:
Muhua, Yang, Christina, Gallo-Ebert, Michael, Hayward, Weidong, Liu, Virginia, McDonough, Joseph T, Nickels
Publikováno v:
Mol Cell Biol
Genome-wide association studies (GWAS) have linked IGF2BP2 single-nucleotide polymorphisms (SNPs) with type 2 diabetes (T2D). Mice overexpressing mIGF2BP2 have elevated cholesterol levels when fed a diet that induces hepatic steatosis. These and othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2477cbdc24d8a84aa9fc7223ba8ec690
https://pubmed.ncbi.nlm.nih.gov/32482798
https://pubmed.ncbi.nlm.nih.gov/32482798