Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joseph T. Greene"'
Autor:
Song Yi Bae, Hannah E. Bergom, Abderrahman Day, Joseph T. Greene, Zoi E. Sychev, Gabrianne Larson, Eva Corey, Stephen R. Plymate, Tanya S. Freedman, Justin H. Hwang, Justin M. Drake
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer. NEPC is characterized by the loss of androgen receptor (AR) signaling and transdifferentiation toward small-cell neuroendocrine (SCN) phenotypes, which results i
Externí odkaz:
https://doaj.org/article/3e48ddb167a545a593cf9fd00b156061
Publikováno v:
Curr Opin Immunol
Myeloid cells (macrophages, monocytes, dendritic cells, and granulocytes) survey the body for signs of infection and tissue damage and regulate tissue homeostasis, organogenesis, and immunity. They express receptors that initiate the inflammatory res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356e5544f396e229cdcd7f87930f4729
https://doi.org/10.1016/j.coi.2021.09.004
https://doi.org/10.1016/j.coi.2021.09.004
Autor:
Anna S. Jaeger, Chelsea M. Crooks, Andrea M. Weiler, Mason I. Bliss, Sierra Rybarczyk, Alex Richardson, Morgan Einwalter, Eric Peterson, Saverio Capuano, Alison Barkhymer, Jordan T. Becker, Joseph T. Greene, Tanya S. Freedman, Ryan A. Langlois, Thomas C. Friedrich, Matthew T. Aliota
Spondweni virus (SPONV) is the closest known relative of Zika virus (ZIKV). SPONV pathogenesis resembles that of ZIKV in pregnant mice, and both viruses are transmitted byAedes aegyptimosquitoes. We aimed to develop a translational model to further u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef5a09d6a66444880fd070933b6fec4
https://doi.org/10.1101/2022.12.16.520792
https://doi.org/10.1101/2022.12.16.520792
Autor:
Ben F. Brian, Monica L. Sauer, Joseph T. Greene, S. Erandika Senevirathne, Anders J. Lindstedt, Olivia L. Funk, Brian L. Ruis, Luis A. Ramirez, Jennifer L. Auger, Whitney L. Swanson, Myra G. Nunez, Branden S. Moriarity, Clifford A. Lowell, Bryce A. Binstadt, Tanya S. Freedman
Publikováno v:
Science advances, vol 8, iss 16
Here, we report that the LynB splice variant of the Src-family kinase Lyn exerts a dominant immunosuppressive function in vivo, whereas the LynA isoform is uniquely required to restrain autoimmunity in female mice. We used CRISPR-Cas9 gene editing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79a31ea6ce138ddaa264f5f1d06771d
https://escholarship.org/uc/item/4pr231mw
https://escholarship.org/uc/item/4pr231mw
Autor:
John C. Byrd, Frank Frissora, Kevan Zapolnik, Xiaokui Mo, Mary K. McKenna, Minh Tran, Rahul Ramaswamy, Vivek M. Rangnekar, Rajeswaran Mani, Ronni Wasmuth, Bonnie K. Harrington, Subbarao Bondada, Joseph T. Greene, Natarajan Muthusamy, Max Yano
Publikováno v:
Blood Advances. 3:1255-1266
Prostate apoptosis response 4 (Par-4) is a tumor suppressor that prevents proliferation and induces cell death in several solid tumors. However, its role in B-cell malignancies has not been elucidated. To describe the role of Par-4 in chronic lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85969fde6cc8ea316eb713b8c813388
https://doi.org/10.1182/bloodadvances.2018025973
https://doi.org/10.1182/bloodadvances.2018025973
Publikováno v:
Tumor Suppressor Par-4 ISBN: 9783030805579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66af301ac39a3e10394fe1acd13c6bc1
https://doi.org/10.1007/978-3-030-80558-6_9
https://doi.org/10.1007/978-3-030-80558-6_9
Autor:
Shuai Dong, Ronni Wasmuth, Amy Lehman, Minh Tran, Meixiao Long, Joseph T. Greene, Natarajan Muthusamy, Amy J. Johnson, John C. Byrd, Jennifer R. Brown, Eileen Y. Hu, Bonnie K. Harrington
Publikováno v:
Journal of Clinical Investigation. 129:122-136
Targeted therapy with small molecules directed at essential survival pathways in leukemia represents a major advance, including the phosphatidylinositol-3′-kinase (PI3K) p110δ inhibitor idelalisib. Here, we found that genetic inactivation of p110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a3080b92f9c3bce7717d3741750e07
https://doi.org/10.1172/jci99386
https://doi.org/10.1172/jci99386
Autor:
Kathryn L. Perry, Karine Z. Oben, Mary K. McKenna, Joseph T. Greene, Roger A. Fleischman, Rajeswaran Mani, Vivek M. Rangnekar, James P. Collard, Sunil K. Noothi, Eric B. Durbin, Jacqueline R. Rivas, Chi Wang, Gerhard C. Hildebrandt, John C. Byrd, Subbarao Bondada, Natarajan Muthusamy, Sara S. Alhakeem
Prostate apoptosis response-4 (Par-4), a proapoptotic tumor suppressor protein, is downregulated in many cancers including renal cell carcinoma, glioblastoma, endometrial, and breast cancer. Par-4 induces apoptosis selectively in various types of can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5abae9e7e46e9d951ec7caff995df23
https://europepmc.org/articles/PMC6024641/
https://europepmc.org/articles/PMC6024641/
IGF1R- and ROR1-Specific Chimeric Antigen Receptor (CAR) T Cell Immunotherapy for Poor Risk Sarcomas
Autor:
Catherine M. Albert, Sophia X. Zhou, Haein Park, Joseph T. Greene, Deepali Sachdev, David M. Loeb, Xianzheng Zhou, Erin Mulvey, Xin Huang, Carl V. Hamby, James Pao, Mitchell S. Cairo, Douglas Yee, Christoph Rader
Publikováno v:
Biology of Blood and Marrow Transplantation. 21(2):S52-S53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c53f6a2080ccea32a6074556b6846f
Autor:
Mary Kathryn McKenna, Sunil K Nooti, Sara Samir Alhakeem, Beth W Gachuki, Frank Frissora, Joseph T Greene, John C Byrd, Natarajan Muthusamy, Vivek R Rangnekar, Subbarao Bondada
Publikováno v:
The Journal of Immunology. 196:72.15-72.15
Chronic Lymphocytic Leukemia (CLL), the most common adult leukemia in the western world, is characterized by accumulation of clonally expanded CD5+CD19+ B lymphocytes in blood and secondary lymphoid organs with impaired apoptotic mechanisms. Prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5230b36e2da3e3618f24cae3dd0513
https://doi.org/10.4049/jimmunol.196.supp.72.15
https://doi.org/10.4049/jimmunol.196.supp.72.15