Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joseph T Vecchi"'
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0308389 (2024)
Micro and nanoscale patterning of surface features and biochemical cues have emerged as tools to precisely direct neurite growth into close proximity with next generation neural prosthesis electrodes. Biophysical cues can exert greater influence on n
Externí odkaz:
https://doaj.org/article/1783503a31954ee88b7bb51677b18b8d
Autor:
Josue A. Lopez, Annamarie Yamamoto, Joseph T. Vecchi, Jussara Hagen, Kyungmoo Lee, Milan Sonka, Marlan R. Hansen, Amy Lee
Publikováno v:
Scientific Reports. 13
Caldendrin is a Ca2+ binding protein that interacts with multiple effectors, such as the Cav1 L-type Ca2+ channel, which play a prominent role in regulating the outgrowth of dendrites and axons (i.e., neurites) during development and in response to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdd7c150eaaeb12627560724a8da2900
https://doi.org/10.1038/s41598-023-29622-9
https://doi.org/10.1038/s41598-023-29622-9
Caldendrin is a calmodulin-like Ca2+ binding protein that is expressed primarily in neurons and regulates multiple effectors including Cav1 L-type Ca2+ channels. Here, we tested the hypothesis that caldendrin regulates Cav1-dependent pathways that re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d5d43f2db605421d3500b276cae0aeb
https://doi.org/10.1101/2021.07.26.453831
https://doi.org/10.1101/2021.07.26.453831
Autor:
Marlan R. Hansen, Kristy Truong, Linjing Xu, Braden Leigh, C. Allan Guymon, Reid Bartholomew, Joseph T. Vecchi
Publikováno v:
Hear Res
Functional outcomes with neural prosthetic devices, such as cochlear implants, are limited in part due to physical separation between the stimulating elements and the neurons they stimulate. One strategy to close this gap aims to precisely guide neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92596d8601a42b53d9c6fa69f757f39
https://europepmc.org/articles/PMC8419132/
https://europepmc.org/articles/PMC8419132/
BackgroundDuring development or regeneration, neurons extend processes (i.e., neurites) via mechanisms that can be readily analyzed in culture. However, defining the impact of a drug or genetic manipulation on such mechanisms can be challenging due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c578395982154c9f9cc432fc806976
https://doi.org/10.1101/2021.03.31.437885
https://doi.org/10.1101/2021.03.31.437885
Publikováno v:
J Neurosci Methods
Background During development or regeneration, neurons extend processes (i.e., neurites) via mechanisms that can be readily analyzed in culture. However, defining the impact of a drug or genetic manipulation on such mechanisms can be challenging due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ace4ef497e5cc43049f86d9735e3db8
https://doi.org/10.1016/j.jneumeth.2021.109349
https://doi.org/10.1016/j.jneumeth.2021.109349
Publikováno v:
Journal of Evolving Stem Cell Research. 1:1-11
Calcium (Ca2+) plays a central role in regulating many biological processes in the cell from muscle contraction to neurotransmitter release. The need for reliable fluorescent calcium indicator dyes is of vast importance for studying many aspects of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9807a4f4c66b0329dd07398cb81cfd
https://doi.org/10.14302/issn.2574-4372.jesr-16-1395
https://doi.org/10.14302/issn.2574-4372.jesr-16-1395
Autor:
Peiman Hematti, David Antonio Cantu, Weiyuan John Kao, Joseph T. Vecchi, Warren E. Rose, Alberto Daniel Guerra
Publikováno v:
The AAPS Journal. 17:620-630
Mesenchymal stromal/stem cells (MSCs) have demonstrated favorable wound healing properties in addition to their differentiation capacity. MSCs encapsulated in biomaterials such as gelatin and polyethylene glycol (PEG) composite hydrogels have display
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37adce026b298549f2deeef872060ce8
https://doi.org/10.1208/s12248-015-9728-6
https://doi.org/10.1208/s12248-015-9728-6
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Cochlear implants (CI) represent incredible devices that restore hearing perception for those with moderate to profound sensorineural hearing loss. However, the ability of a CI to restore complex auditory function is limited by the number of perceptu
Externí odkaz:
https://doaj.org/article/147787eb97a444c9be566c94d3f94253
Autor:
Joseph T. Vecchi, Sean Mullan, Josue A. Lopez, Madeline Rhomberg, Annamarie Yamamoto, Annabelle Hallam, Amy Lee, Milan Sonka, Marlan R. Hansen
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Quantitative analysis of neurite growth and morphology is essential for understanding the determinants of neural development and regeneration, however, it is complicated by the labor-intensive process of measuring diverse parameters of neuri
Externí odkaz:
https://doaj.org/article/ffee560dea1943709190c9d6c07ff905