Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joseph Saad"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Epigenetic research involves examining the mitotically heritable processes that regulate gene expression, independent of changes in the DNA sequence. Recent technical advances such as whole-genome bisulfite sequencing and affordable epigenomic array-
Externí odkaz:
https://doaj.org/article/0cafea2f6db6473a8e9fdc09ed44c8e4
Autor:
Aarif M. N. Batcha, Nele Buckup, Stefanos A. Bamopoulos, Vindi Jurinovic, Maja Rothenberg-Thurley, Hanna Gittinger, Bianka Ksienzyk, Annika Dufour, Stephanie Schneider, Mika Kontro, Joseph Saad, Caroline A. Heckmann, Cristina Sauerland, Dennis Görlich, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Ulrich Mansmann, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold
Publikováno v:
Blood Advances. 7:1040-1044
Autor:
Samuli Eldfors, Joseph Saad, Nemo Ikonen, Disha Malani, Bjørn Tore Gjertsen, Mika Kontro, Kimmo Porkka, Caroline A. Heckman
Monosomy 7 and del(7q) (-7/-7q) are frequent chromosomal abnormalities detected in up to 10% of acute myeloid leukemia (AML) patients. Despite unfavorable treatment outcomes, no approved targeted therapies exist for patients with -7/-7q. Therefore, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca792fb51f556a54e43d1f6004337a74
https://doi.org/10.1101/2023.04.08.23287765
https://doi.org/10.1101/2023.04.08.23287765
Autor:
Joseph Saad, Samuli Eldfors, Vilma Ikonen, Bjørn Tore Gjertsen, Mika Kontro, Kimmo Porkka, Caroline A. Heckman
Publikováno v:
Blood. 140:1033-1035
Autor:
Ana Rio-Machin, Findlay Bewicke-Copley, Jiexin Zheng, Pedro Casado Izquierdo, Juho J. Miettinen, Naeem Khan, Jonas Demeulemeester, Szilvia Krizsán, Christopher Middleton, Sam Benkwitz-Bedford, Joseph Saad, Amaia Vilas-Zornoza, Teresa Ezponda, William Grey, Vincent-Philippe Lavallée, Alexis Nolin-Lapalme, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Ryan J Colm, Jonathan Bond, Doriana Di Bella, Krister Wennerberg, Alun Parsons, Andy G.X. Zeng, Hannah Armes, Karina Close, Fadimana Kaya, Kevin Rouault-Pierre, John G. Gribben, Felipe Prosper, James Cavenagh, John E. Dick, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, Guy Sauvageau, Kimmo Porkka, Caroline A. Heckman, Jun Wang, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro Cutillas, Jude Fitzgibbon
Publikováno v:
Blood. 140:1030-1032
Autor:
Olli Dufva, Heikki Kuusanmäki, Markus Vaha-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan Awad, Cristina Mancebo, Joseph Saad, Juho J. Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Ulla Wartiovaara-Kautto, Marina Konopleva, Mikko A Keränen, Kimmo Porkka, Krister Wennerberg, Mika Kontro, Caroline A. Heckman, Satu Mustjoki
Publikováno v:
Blood. 140:101-103
Autor:
Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Vänttinen, Petra Nygren, Jay Klievink, Jonas Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho Miettinen, Komal K. Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A. Heckman, Satu Mustjoki
Funding Information: This study was supported by the Cancer Foundation Finland, the Helsinki Institute of Life Science (HiLIFE) Fellow grants, the Academy of Finland (grant 1320185 ), the Sigrid Jusélius Foundation , the Finnish Cancer Institute , t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148477e5b4c49fcc3edbc9051a7877b4
https://aaltodoc.aalto.fi/handle/123456789/120373
https://aaltodoc.aalto.fi/handle/123456789/120373
Autor:
Ujunwa Cynthia Okoye-Okafor, Komal K. Javarappa, Dimitrios Tsallos, Joseph Saad, Daozheng Yang, Chi Zhang, Lumie Benard, Victor J. Thiruthuvanathan, Sally Cole, Stephen Ruiz, Madhuri Tatiparthy, Gaurav Choudhary, Stefanie DeFronzo, Boris A. Bartholdy, Celine Pallaud, Pedro Marques Ramos, Aditi Shastri, Amit Verma, Caroline A. Heckman, Britta Will
Publikováno v:
Journal of Experimental Medicine. 219
Publisher Copyright: © 2022 Okoye-Okafor et al. Thrombocytopenia, prevalent in the majority of patients with myeloid malignancies, such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), is an independent adverse prognostic factor. A
Publikováno v:
Journal of the American Academy of Dermatology. 85:AB113
Autor:
Caroline A. Heckman, Gaurav Choudhary, Joseph Saad, Celine Pallaud, Komal Kumar Javarappa, Sally Cole, Britta Will, Boris Bartholdy, Dimitrios Tsallos, Aditi Shastri, Victor Thiruthuvanathan, Amit Verma, Pedro Marques Ramos, Stephen Ruiz, Lumie Benard, Ujunwa C. Okoye-Okafor, Stefanie DeFronzo, Madhuri Tatiparthy
Publikováno v:
Experimental Hematology. 88:S45-S46
Thrombocytopenia defined as platelet counts of Several studies evaluating the use of thrombopoietin receptor agonists (TPO-RA) for the clinical management of thrombocytopenia have shown promising clinical results. TPO-RA eltrombopag (EP) which has be