Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Joseph S. Stephan"'
Autor:
Reine Khoury, Joelle Saad, Vanessa Jabre, Litsa Maria Ghayad, Mohamad Khalifeh, Rouba Houbeika, Perla El Ahmad, Amar Mezher, Diala El Masri, Zena Haddad, Fady Eid, Nour Barmo, Patrick Nasrallah, Sama F. Sleiman, Joseph S. Stephan
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e14705- (2023)
Exercise promotes learning and memory recall as well as rescues cognitive decline associated with aging. The positive effects of exercise are mediated by circulatory factors that predominantly increase Brain Derived Neurotrophic Factor (BDNF) signali
Externí odkaz:
https://doaj.org/article/00dd057834234bb9a4172f542d0ff0fd
Autor:
Joseph S. Stephan, Sama F. Sleiman
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Stroke is one of the leading causes of death and disability in the world. Stroke not only affects the patients, but also their families who serve as the primary caregivers. Discovering novel therapeutic targets for stroke is crucial both from a quali
Externí odkaz:
https://doaj.org/article/ea8c8dd8728e4092b570b9d3dc425323
Autor:
Patrick Nasrallah, Edwina Abou Haidar, Joseph S. Stephan, Lauretta El Hayek, Nabil Karnib, Mohamad Khalifeh, Nour Barmo, Vanessa Jabre, Rouba Houbeika, Anthony Ghanem, Jason Nasser, Nadine Zeeni, Maya Bassil, Sama F. Sleiman
Publikováno v:
Neurobiology of Stress, Vol 11, Iss , Pp - (2019)
How individuals respond to chronic stress varies. Susceptible individuals ultimately develop depression; whereas resilient individuals live normally. In this study, our objective was to examine the effect of branched-chain amino acids (BCAA), commonl
Externí odkaz:
https://doaj.org/article/0b9390ce40f84bf18be12eec0b478487
Autor:
Joseph S. Stephan, Luana Fioriti, Nayan Lamba, Luca Colnaghi, Kevin Karl, Irina L. Derkatch, Eric R. Kandel
Publikováno v:
Cell Reports, Vol 11, Iss 11, Pp 1772-1785 (2015)
The mouse cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is a translational regulator implicated in long-term memory maintenance. Invertebrate orthologs of CPEB3 in Aplysia and Drosophila are functional prions that are physiologically
Externí odkaz:
https://doaj.org/article/f040c1706bad4537b7237eebac99412b
Autor:
Marc Fakhoury, Fady Eid, Perla El Ahmad, Reine Khoury, Amar Mezher, Diala El Masri, Zena Haddad, Yara Zoghbi, Litsa Maria Ghayad, Sama F. Sleiman, Joseph S. Stephan
Publikováno v:
Brain plasticity (Amsterdam, Netherlands). 8(1)
The term “neural plasticity” was first used to describe non-pathological changes in neuronal structure. Today, it is generally accepted that the brain is a dynamic system whose morphology and function is influenced by a variety of factors includi
Autor:
Maya S. Abdallah, Joseph S. Stephan, Wissam H. Faour, Wassim N. Shebaby, Carole Dagher-Hamalian, Nadine Zeeni, Zeina Harhous
Publikováno v:
Inflammation Research. 69:1019-1026
Ghrelin has a key role in modulating energy metabolism and weight gain. The present study aimed at studying the potential role of ghrelin in the development and/or exacerbation of organ damage in a mouse model of diet-induced obesity. Adult mice were
Autor:
Pascal Ibrahim, Edwina Abou Haidar, Lauretta El Hayek, Sama F. Sleiman, Maria Bilen, Vanessa Jabre, Joseph S. Stephan, Nour Barmo, Mohamad Khalifeh, Nabil Karnib, Rouba Houbeika
Publikováno v:
Psychopharmacology. 237:3007-3020
Previous studies suggested that methionine (Met) levels are decreased in depressed patients. However, whether the decrease in this amino acid is important for phenotypic behaviors associated with depression has not been deciphered. The response of in
Exercise factors as potential mediators of cognitive rehabilitation following traumatic brain injury
Autor:
Sama F. Sleiman, Joseph S. Stephan
Publikováno v:
Current Opinion in Neurology. 32:808-814
Purpose of review To summarize what is known about how exercise mediates cognitive rehabilitation post traumatic brain injury (TBI). Recent findings TBI is a devastating condition that leads to cognitive, motor and social deficits with significant so
Autor:
Maya Abdallah, Joseph S. Stephan, Assaad A. Eid, Wissam H. Faour, Nabil El Zein, Mohammad Mroueh, Sola Aoun Bahous, Costantine F. Daher
Publikováno v:
Cell Biochemistry and Function. 37:245-255
Damage to podocytes is a key event in glomerulopathies. While energy dense food can contribute to kidney damage, the role of the orixegenic hormone "ghrelin" in podocyte biology is still unknown. In the present study, we investigated the effect of gh
Autor:
Maria Bilen, Rajiv R. Ratan, Vanessa Jabre, Nour Barmo, Edward B. Holson, Pascale Ibrahim, Patrick Nasrallah, Rim El-Ghandour, Lauretta El Hayek, Mohamad Khalifeh, Sama F. Sleiman, Joseph S. Stephan, Nabil Karnib
Publikováno v:
Neuropsychopharmacology
Chronic stress promotes depression in some individuals, but has no effect in others. Susceptible individuals exhibit social avoidance and anxious behavior and ultimately develop depression, whereas resilient individuals live normally. Exercise counte