Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Joseph S. Lipsick"'
Autor:
Paul J. Vorster, Paul Goetsch, Tilini U. Wijeratne, Keelan Z. Guiley, Laura Andrejka, Sarvind Tripathi, Braden J. Larson, Seth M. Rubin, Susan Strome, Joseph S. Lipsick
Publikováno v:
Biology Open, Vol 9, Iss 5 (2020)
The five-protein MuvB core complex is highly conserved in animals. This nuclear complex interacts with RB-family tumor suppressor proteins and E2F-DP transcription factors to form DREAM complexes that repress genes that regulate cell cycle progressio
Externí odkaz:
https://doaj.org/article/5af2d70fe94a4b07b07a96c7fd3de521
Publikováno v:
Biology Open, Vol 6, Iss 7, Pp 967-978 (2017)
The conserved multi-protein MuvB core associates with the Myb oncoproteins and with the RB-E2F-DP tumor suppressor proteins in complexes that regulate cell proliferation, differentiation, and apoptosis. Drosophila Mip120, a homolog of LIN54, is a seq
Externí odkaz:
https://doaj.org/article/3023a7dd36804162b176641e739e6ff4
Publikováno v:
Biology Open, Vol 2, Iss 2, Pp 101-110 (2012)
Summary Gene duplication is an important means of generating new genes. The major mechanisms by which duplicated genes are preserved in the face of purifying selection are thought to be neofunctionalization, subfunctionalization, and increased gene d
Externí odkaz:
https://doaj.org/article/57dd789c08d44a9db245e712c957171d
Autor:
Nicholas Barasch, Xue Gong, Kevin A Kwei, Sushama Varma, Jewison Biscocho, Kunbin Qu, Nan Xiao, Joseph S Lipsick, Robert J Pelham, Robert B West, Jonathan R Pollack
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171265 (2017)
Pathogenic gene fusions have been identified in several histologic types of salivary gland neoplasia, but not previously in acinic cell carcinoma (AcCC). To discover novel gene fusions, we performed whole-transcriptome sequencing surveys of three AcC
Externí odkaz:
https://doaj.org/article/614af5fbee1a4ef991eedc4a5ab3af7a
Autor:
Tilini U. Wijeratne, Susan Strome, Braden J. Larson, Paul J. Vorster, Seth M. Rubin, Laura Andrejka, Paul D. Goetsch, Joseph S. Lipsick, Sarvind Tripathi, Keelan Z. Guiley
Publikováno v:
Biology open, vol 9, iss 5
Biology Open, Vol 9, Iss 5 (2020)
Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 9, Iss 5 (2020)
Biology Open
article-version (VoR) Version of Record
The five-protein MuvB core complex is highly conserved in animals. This nuclear complex interacts with RB-family tumor suppressor proteins and E2F-DP transcription factors to form DREAM complexes that repress genes that regulate cell cycle progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84cdfaf99c9d32c12de2f2cc0be9778
https://escholarship.org/uc/item/66v885zv
https://escholarship.org/uc/item/66v885zv
Autor:
Joseph S. Lipsick
Publikováno v:
Cold Spring Harb Perspect Biol
Early studies of transmissible tumors in chickens provided evidence that viruses such as avian leukosis virus (ALV) and Rous sarcoma virus (RSV) can cause cancer in these animals. Doubts about the relevance to human tumors and failures to replicate s
Publikováno v:
Biology Open, Vol 6, Iss 7, Pp 967-978 (2017)
The conserved multi-protein MuvB core associates with the Myb oncoproteins and with the RB-E2F-DP tumor suppressor proteins in complexes that regulate cell proliferation, differentiation, and apoptosis. Drosophila Mip120, a homolog of LIN54, is a seq
Autor:
Joseph S. Lipsick
Publikováno v:
Cold Spring Harb Perspect Med
Observations of the incidence of tumors among chimney sweeps in the eighteenth century and later experiments with coal tars provided early evidence that carcinogens in the environment can promote cancer. Subsequent studies of individuals exposed to r
Autor:
Joseph S. Lipsick
Publikováno v:
Cold Spring Harb Perspect Biol
Tumor suppressor genes encode critical intracellular regulators, such as the retinoblastoma protein. They control processes including cell proliferation, cell survival, and responses to DNA damage and are frequently mutated in cancer. In this excerpt
Autor:
Seth M. Rubin, Sarvind Tripathi, Siddharth Saini, Larisa Litovchick, Audra N. Iness, Keelan Z. Guiley, Joseph S. Lipsick
The MuvB transcriptional regulatory complex, which controls cell-cycle-dependent gene expression, cooperates with B-Myb to activate genes required for the G2 and M phases of the cell cycle. We have identified the domain in B-Myb that is essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6520b4cae5ce77967f130228875247de
https://europepmc.org/articles/PMC6176624/
https://europepmc.org/articles/PMC6176624/