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pro vyhledávání: '"Joseph S. Fisher"'
Autor:
Joseph S. Fisher, Daryl M. Mayes, Michael L. Tuck, Greg J. Berg, David B. Fittingoff, James R. Sowers, Norman D. Asp
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 52:1057-1061
Spironolactone, a mineralocorticoid antagonist, may also inhibit aldosterone biosynthesis. In vitro studies suggest that spironolactone and its major metabolites inhibit adrenal 18- and 11 beta-hydroxylase activity. We examined various adrenal cortic