Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joseph S. Bowness"'
Autor:
Joseph S. Bowness, Tatyana B. Nesterova, Guifeng Wei, Lisa Rodermund, Mafalda Almeida, Heather Coker, Emma J. Carter, Artun Kadaster, Neil Brockdorff
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110830- (2022)
Summary: X chromosome inactivation (XCI) is mediated by the non-coding RNA Xist, which directs chromatin modification and gene silencing in cis. The RNA binding protein SPEN and associated corepressors have a central role in Xist-mediated gene silenc
Externí odkaz:
https://doaj.org/article/cbb4ebeca8874aee9b97248ef77766d9
Autor:
Tatyana B. Nesterova, Guifeng Wei, Heather Coker, Greta Pintacuda, Joseph S. Bowness, Tianyi Zhang, Mafalda Almeida, Bianca Bloechl, Benoit Moindrot, Emma J. Carter, Ines Alvarez Rodrigo, Qi Pan, Ying Bi, Chun-Xiao Song, Neil Brockdorff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.
Externí odkaz:
https://doaj.org/article/1099fcaec9864035a2a87b2701f1ba55
Autor:
Neil Brockdorff, Aaron T. L. Lun, Joseph S Bowness, John C. Marioni, Daniel J. Gaffney, Rebecca V Berrens, Guocheng Lan, Florian Bieberich, Andrian Yang, Maria Imaz, Cheuk-Ting Law, Christopher E. Laumer
Publikováno v:
Nature Biotechnology. 40:546-554
Transposable elements (TEs) regulate diverse biological processes, from early development to cancer. Expression of young TEs is difficult to measure with next-generation, single-cell sequencing technologies because their highly repetitive nature mean
Publikováno v:
Genes Dev
The X inactive-specific transcript (Xist) gene is the master regulator of X chromosome inactivation in mammals. Xist produces a long noncoding (lnc)RNA that accumulates over the entire length of the chromosome from which it is transcribed, recruiting
Autor:
Mafalda Almeida, Joseph S Bowness, Jernej Ule, Greta Pintacuda, Heather Coker, Neil Brockdorff, Guifeng Wei
RNA N6-methyladenosine (m6A) modification plays important roles in multiple aspects of RNA regulation. m6A is installed cotranscriptionally by the METTL3/14 complex, but its direct roles in RNA processing remain unclear. Here, we investigate the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7411d4e30b73e82fcd08dce1b5537e
https://ora.ox.ac.uk/objects/uuid:82b04333-1c12-4f8c-beba-8c668299f843
https://ora.ox.ac.uk/objects/uuid:82b04333-1c12-4f8c-beba-8c668299f843
Autor:
Neil Brockdorff, Lothar Schermelleh, Bramman Rajkumar, Tatyana B. Nesterova, David Miguel Susano Pinto, Joseph S Bowness, Heather Coker, Lisa Rodermund, Roel Oldenkamp, Guifeng Wei
Xist RNA directs the process of X-chromosome inactivation in mammals by spreading in cis along the chromosome from which it is transcribed and recruiting chromatin modifiers to silence gene transcription. To elucidate mechanisms of Xist RNA cis-confi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1bc22dac2f2f6e5ff29d80a69174fd6
https://doi.org/10.1101/2020.11.24.396473
https://doi.org/10.1101/2020.11.24.396473
Publikováno v:
Developmental Cell. 56:1234-1235
Autor:
Rebecca V, Berrens, Andrian, Yang, Christopher E, Laumer, Aaron T L, Lun, Florian, Bieberich, Cheuk-Ting, Law, Guocheng, Lan, Maria, Imaz, Joseph S, Bowness, Neil, Brockdorff, Daniel J, Gaffney, John C, Marioni
Publikováno v:
Nature biotechnology. 40(4)
Transposable elements (TEs) regulate diverse biological processes, from early development to cancer. Expression of young TEs is difficult to measure with next-generation, single-cell sequencing technologies because their highly repetitive nature mean
Autor:
Neil Brockdorff, Jernej Ule, Guifeng Wei, Mafalda Almeida, Joseph S Bowness, Greta Pintacuda, Heather Coker
RNAN6-methyladenosine (m6A) modification plays important roles in multiple aspects of RNA regulation. m6A is installed co-transcriptionally by the METTL3/14 complex, but its direct roles in RNA processing remain unclear. Here we investigate the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d933e9330d5d799851bf06d3d04226
https://doi.org/10.1101/2020.09.10.291179
https://doi.org/10.1101/2020.09.10.291179
Autor:
Guifeng, Wei, Mafalda, Almeida, Greta, Pintacuda, Heather, Coker, Joseph S, Bowness, Jernej, Ule, Neil, Brockdorff
Publikováno v:
Genome Res
RNA N(6)-methyladenosine (m(6)A) modification plays important roles in multiple aspects of RNA regulation. m(6)A is installed cotranscriptionally by the METTL3/14 complex, but its direct roles in RNA processing remain unclear. Here, we investigate th