Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Joseph S Harrison"'
Autor:
Christopher J Petell, Kathyrn Randene, Michael Pappas, Diego Sandoval, Brian D Strahl, Joseph S Harrison, Joshua P Steimel
Publikováno v:
eLife, Vol 10 (2021)
Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ra
Externí odkaz:
https://doaj.org/article/3244e8957e2b4851885fa8b644198db3
Autor:
Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000975 (2020)
The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase and critical regulator of cell cycle progression. Despite its vital role, it has remained challenging to globally map APC/C substrates. By combining orthogonal features of kno
Externí odkaz:
https://doaj.org/article/5996078700384ca5bbd42dde1d166f90
Autor:
Joseph S Harrison, Evan M Cornett, Dennis Goldfarb, Paul A DaRosa, Zimeng M Li, Feng Yan, Bradley M Dickson, Angela H Guo, Daniel V Cantu, Lilia Kaustov, Peter J Brown, Cheryl H Arrowsmith, Dorothy A Erie, Michael B Major, Rachel E Klevit, Krzysztof Krajewski, Brian Kuhlman, Brian D Strahl, Scott B Rothbart
Publikováno v:
eLife, Vol 5 (2016)
The epigenetic inheritance of DNA methylation requires UHRF1, a histone- and DNA-binding RING E3 ubiquitin ligase that recruits DNMT1 to sites of newly replicated DNA through ubiquitylation of histone H3. UHRF1 binds DNA with selectivity towards hemi
Externí odkaz:
https://doaj.org/article/a0c4f588bf4d4946bb43d1fe3709ba4c
Autor:
Hari B Kamadurai, Yu Qiu, Alan Deng, Joseph S Harrison, Chris MacDonald, Marcelo Actis, Patrick Rodrigues, Darcie J Miller, Judith Souphron, Steven M Lewis, Igor Kurinov, Naoaki Fujii, Michal Hammel, Robert Piper, Brian Kuhlman, Brenda A Schulman
Publikováno v:
eLife, Vol 2 (2013)
Ubiquitination by HECT E3 enzymes regulates myriad processes, including tumor suppression, transcription, protein trafficking, and degradation. HECT E3s use a two-step mechanism to ligate ubiquitin to target proteins. The first step is guided by inte
Externí odkaz:
https://doaj.org/article/ee078a0126a4411894d3182965482e78
Autor:
Kellan P. Weston, Xiaoyi Gao, Jinghan Zhao, Kwang-Soo Kim, Susan E. Maloney, Jill Gotoff, Sumit Parikh, Yen-Chen Leu, Kuen-Phon Wu, Marwan Shinawi, Joshua P. Steimel, Joseph S. Harrison, Jason J. Yi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
UBE3A gene dysregulation is associated with neurodevelopmental disorders, but predicting the function of UBE3A variants remains difficult. The authors use a high-throughput assay to categorize variants by functional activity, and show that UBE3A hype
Externí odkaz:
https://doaj.org/article/558b49ad0b204a65b82f15573d8dfef0
Publikováno v:
Entrepreneurship Theory and Practice. 47:495-523
Strategic entrepreneurship integrates the fields of strategy and entrepreneurship to consider firms’ simultaneous engagement in opportunity- and advantage-seeking behaviors to create wealth. Since its conceptualization in the early 2000s, the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aafee352a797bbc971524ee1d896a72
https://doi.org/10.1177/10422587221111727
https://doi.org/10.1177/10422587221111727
Autor:
Shavin Malhotra, Joseph S. Harrison
Publikováno v:
Strategic Management Journal. 43:2809-2828
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8649f44f7e37edbbb1c00a2cb660914
https://doi.org/10.1002/smj.3415
https://doi.org/10.1002/smj.3415
Publikováno v:
Methods to Improve Our Field ISBN: 9781804553657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e167a786a65f69ee8938e0cb69d60093
https://doi.org/10.1108/s1479-838720220000014006
https://doi.org/10.1108/s1479-838720220000014006
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 605-615 (2015)
This article provides information to support the database article titled “UbSRD: The Ubiquitin Structural Relational Database” (Harrison et al., 2015) [1] . The ubiquitin-like homology fold (UBL) represents a large family that encompasses both po
Externí odkaz:
https://doaj.org/article/f60f3ad331074ff8b03fe0ac7f8182ee
Publikováno v:
Strategic Management Journal. Wiley-Blackwell
Research SummaryHuman coding of unstructured text can enable scholars to measure complex latent constructs for use in empirical analysis, but also requires substantial time and resources that limit the number and sample sizes of studies using this ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9557304532a1e4a7a6b4e23c6434309
https://doi.org/10.1002/smj.3480
https://doi.org/10.1002/smj.3480