Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joseph Raymond Winkle"'
Autor:
Candace M. Trout, David W. Wheeler, Joseph Raymond Winkle, Caryn M. Thompson, W. Hunter White
Publikováno v:
Veterinary parasitology. 258
Spinetoram is the newest member the spinosyn-class of natural products to be commercialized for flea control on cats in the United States under the tradename Cheristin® for cats. This report describes results from two laboratory studies and a multi-
Autor:
Yasheen Zhou, Defauw Jean Marie, Terry William Balko, Eric E. Easom, Wuxin Zou, Jianxin Cao, Tsutomu Akama, Yong-Kang Zhang, Joseph Raymond Winkle, Jian Xue, Wei Bu, Jacob J. Plattner, Shenghai Guo, W. Hunter White
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5589-5593
A novel series of isoxazoline benzoxaborole small molecules was designed and synthesized for a structure-activity relationship (SAR) investigation to assess the ectoparasiticide activity against ticks and fleas. The study identified an orally bioavai
Autor:
Anthony J. Rumschlag, William G. Ryan, Joseph Raymond Winkle, Tandy Paarlberg, Daniel E. Snyder, Lisa Marie Young
Publikováno v:
Parasites & Vectors
Background A spot-on spinetoram formulation (Cheristin®) was developed to eliminate fleas from infested cats. This paper describes three spinetoram studies: two for registration (Studies 1 and 2), and one comparing residual speed of kill (SOK) with
Autor:
Jianzhang Yang, Joseph Raymond Winkle, Jacob J. Plattner, Yong-Kang Zhang, Zhixin Ge, Eric E. Easom, Jianxin Cao, Terry William Balko, Yasheen Zhou, Defauw Jean Marie, W. Hunter White, Tsutomu Akama
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(13)
Novel isoxazoline amide benzoxaboroles were designed and synthesized to optimize the ectoparasiticide activity of this chemistry series against ticks and fleas. The study identified an orally bioavailable molecule, (S)-N-((1-hydroxy-3,3-dimethyl-1,3-
Autor:
Jeffery Alan Meyer, Lori A. Thompson, Kelly M. Credille, Lisa M. Young, Joseph Raymond Winkle
Publikováno v:
Veterinary dermatology. 24(6)
Background A formulation containing 39.6% spinetoram resulted in a higher than anticipated number of reports of alopecia at the site of application in the first months following commercial product launch. Hypothesis/objectives To determine the cause
Autor:
Joseph Raymond Winkle, Robert Starkey, Christine M. McCoy, Jeffery Alan Meyer, W. Hunter White, Philip R. Plummer, Daniel E. Snyder, Connie J. Kemper
Publikováno v:
Journal of economic entomology. 100(1)
The activity of spinosad, imidacloprid, and methomyl baits and technical actives were assessed against susceptible house flies, Musca domestica L. (Diptera: Muscidae). In a feeding assay, imidacloprid affected flies more rapidly than methomyl or spin
Autor:
Sharon A. Naylor, Daniel E. Snyder, Joseph Raymond Winkle, Paul T. Pugh, Thomas V. Worden, J. T. Rothwell, Herbert A. Kirst, Thomas C. Sparks, Lawrence C. Creemer, L. Barry Lowe
Publikováno v:
Current topics in medicinal chemistry. 2(7)
The spinosyns are a novel family of fermentation-derived natural products that exhibit potent insecticidal activities. Spinosad, a naturally-occurring mixture of spinosyn A and spinosyn D, has successfully established its utility for crop protective