Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Joseph R. Williamson"'
Publikováno v:
Clinical Hemorheology and Microcirculation. 7:773-779
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b25ff957f98139d7e2ea8f87ee2e4a
https://doi.org/10.3233/ch-1987-7605
https://doi.org/10.3233/ch-1987-7605
Autor:
Banavara L. Mylari, Peter J. Oates, Charles Kilo, Kathy Chang, Yasudo Ido, Jens R. Nyengaard, Ronald G. Tilton, Joseph R. Williamson
Publikováno v:
Ido, Y, Nyengaard, J R, Chang, K, Tilton, R G, Kilo, C, Mylari, B L, Oates, P J & Williamson, J R 2010, ' Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation ', Antioxidants and Redox Signaling, vol. 12, no. 1, pp. 39-51 . https://doi.org/10.1089/ars.2009.2502
These experiments were undertaken to assess the importance of cytoplasmic (c) sorbitol oxidation versus mitochondrial (m) pyruvate oxidation in mediating neural and vascular dysfunction attributable to hyperglycemia in diabetic rats. Increased oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e59cdc21df6315e6634568f3c0a25cf
https://doi.org/10.1089/ars.2009.2502
https://doi.org/10.1089/ars.2009.2502
Autor:
Joseph R. Williamson, Jaeman Byun, Yasuo Ido, Subramaniam Pennathur, Jay W. Heinecke, Pablo E. Pergola, Ratna S. Danda, Jozsef I. Heller
Publikováno v:
Journal of Biological Chemistry. 280:22706-22714
The pattern of oxidized amino acids in aortic proteins of nonhuman primates suggests that a species resembling hydroxyl radical damages proteins when blood glucose levels are high. However, recent studies argue strongly against a generalized increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8847bad84a22ddce955cf54b37164b2e
https://doi.org/10.1074/jbc.m500839200
https://doi.org/10.1074/jbc.m500839200
Autor:
Robert E. Schmidt, Lucie N. Beaudet, Joseph R. Williamson, Richard G. Peterson, Kevin E. Yarasheski, Denise A. Dorsey, Peter J. Oates, Curtis A. Parvin, Samuel R. Smith
Publikováno v:
Experimental Neurology. 192:407-419
We have developed an animal model of diabetic sympathetic autonomic neuropathy which is characterized by neuroaxonal dystrophy (NAD), an ultrastructurally distinctive axonopathy, in chronic streptozotocin (STZ)-diabetic rats. Diabetes-induced alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb0f607836a556b46111a28660d6238
https://doi.org/10.1016/j.expneurol.2004.12.018
https://doi.org/10.1016/j.expneurol.2004.12.018
Publikováno v:
Diabetes. 53:2931-2938
The primary aim of these experiments was to assess in vitro effects of hyperglycemia (30 mmol/l glucose) and hypoxia (Po2 = 36 torr) of 2-h duration, separately and in combination, on cytosolic and mitochondrial free NADH (NADHc and NADHm, respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf81f04bd8ae340af18a13f6c41c148
https://doi.org/10.2337/diabetes.53.11.2931
https://doi.org/10.2337/diabetes.53.11.2931
Publikováno v:
Proceedings of the National Academy of Sciences. 101:653-658
The mechanism(s) that increase retinal and visual cortex blood flows in response to visual stimulation are poorly understood. We tested the hypothesis that increased transfer of electrons and protons from glucose to cytosolic free NAD + , reducing it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93731ec3492e119200e435ffbbaa4c9
https://doi.org/10.1073/pnas.0307458100
https://doi.org/10.1073/pnas.0307458100