Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joseph R. Pomerening"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33835 (2012)
Mitotic progression in eukaryotic cells depends upon the activation of cyclin-dependent kinase 1 (CDK1), followed by its inactivation through the anaphase-promoting complex (APC)/cyclosome-mediated degradation of M-phase cyclins. Previous work reveal
Externí odkaz:
https://doaj.org/article/fa5422d44f154ea79c7dbf3cb9c05492
Autor:
Thomas DeLuca, Joseph R. Pomerening, Jeremy Sherer, John B. Watkins, John Foley, Helen Chin-Sinex, Kah Tan Allen, Jerry M. Jesseph, Marc S. Mendonca
Publikováno v:
Free Radical Biology and Medicine. 89:263-273
We investigated whether altering Warburg metabolism (aerobic glycolysis) by treatment with the metabolic agent dichloroacetate (DCA) could increase the X-ray-induced cell killing of the radiation-resistant human non-small-cell lung cancer (NSCLC) cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbb965bcbbb64bab5858f7a3a11012b
https://doi.org/10.1016/j.freeradbiomed.2015.08.006
https://doi.org/10.1016/j.freeradbiomed.2015.08.006
Autor:
Joseph R. Pomerening
Publikováno v:
Cell Cycle. 17:9-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f319062de8b4f1fd720886d8fbf19f62
https://doi.org/10.1080/15384101.2017.1389197
https://doi.org/10.1080/15384101.2017.1389197
Autor:
Joseph R. Pomerening, Qing Kang
Publikováno v:
Molecular Biology of the Cell
Cyclin B accumulation in the early Xenopus embryo drives CDK1 oscillations. CDK1 directs a negative-feedback loop upon cyclin B synthesis through the repression of global protein translation, and this attenuation of cyclin B synthesis could improve t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64025e9f61dee9a0f4daa4fb54b384dd
https://doi.org/10.1091/mbc.e11-09-0768
https://doi.org/10.1091/mbc.e11-09-0768
Autor:
Joseph R. Pomerening, Eric M. Machleder, Chi Ying F. Huang, Nikki B. Trunnell, James E. Ferrell, Sun Young Kim, Wen Xiong
Publikováno v:
FEBS Letters. 583:3999-4005
Here we review some of our work over the last decade on Xenopus oocyte maturation, a cell fate switch, and the Xenopus embryonic cell cycle, a highly dynamical process. Our approach has been to start with wiring diagrams for the regulatory networks t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f1c01bd23ae010397fd01a6bb4303a
https://doi.org/10.1016/j.febslet.2009.10.068
https://doi.org/10.1016/j.febslet.2009.10.068
Publikováno v:
Cell. 122(4):565-578
SummaryThe cell-cycle oscillator includes an essential negative-feedback loop: Cdc2 activates the anaphase-promoting complex (APC), which leads to cyclin destruction and Cdc2 inactivation. Under some circumstances, a negative-feedback loop is suffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7399deaec62e05cc090403fcc4c99a6
The mitotic kinase Aurora A (AurA) is regulated by a complex network of factors that includes co-activator binding, autophosphorylation, and dephosphorylation. Dephosphorylation of AurA by PP2A (human, Ser-51; Xenopus, Ser-53) destabilizes the protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae1c392081faf4b94fb20854f87e9e7
https://europepmc.org/articles/PMC4067186/
https://europepmc.org/articles/PMC4067186/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e33835 (2012)
PLoS ONE, Vol 7, Iss 3, p e33835 (2012)
Mitotic progression in eukaryotic cells depends upon the activation of cyclin-dependent kinase 1 (CDK1), followed by its inactivation through the anaphase-promoting complex (APC)/cyclosome-mediated degradation of M-phase cyclins. Previous work reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c1e5a1fd8fcefd772b5bbd839f4097
http://europepmc.org/articles/PMC3315497
http://europepmc.org/articles/PMC3315497