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of 9
pro vyhledávání: '"Joseph R. Latoche"'
Autor:
Mouna eLagraoui, Joseph R. Latoche, Natalia G. Cartwright, Gauthaman eSukumar, Clifton L. Dalgard, Brian C. Schaefer
Publikováno v:
Frontiers in Neurology, Vol 3 (2012)
An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major contributor to TBI-induced brain damage. However, much remains unknown regarding the induction a
Externí odkaz:
https://doaj.org/article/b4ac0dcec4934d08bcf50c436abc09cc
Autor:
Brian C. Schaefer, Mouna Lagraoui, Clifton L. Dalgard, Joseph R. Latoche, Gauthaman Sukumar, Sean K. Maynard
Publikováno v:
Brain, behavior, and immunity. 61
Neuroinflammation plays a critical role in the pathogenesis of traumatic brain injury (TBI). TBI induces rapid activation of astrocytes and microglia, infiltration of peripheral leukocytes, and secretion of inflammatory cytokines. In the context of m
Publikováno v:
JARO: Journal of the Association for Research in Otolaryngology
Studies using inbred strains of mice have been invaluable for identifying alleles that adversely affect hearing. However, the efficacy of those studies is limited by the phenotypes that these strains express and the alleles that they segregate. Here,
Autor:
Joseph R. Latoche, Konrad Noben-Trauth
Publikováno v:
Journal of Biological Chemistry. 286:3079-3093
Inflammation of the middle ear cavity (otitis media) and the abnormal deposition of bone at the otic capsule are common causes of conductive hearing impairment in children and adults. Although a host of environmental factors can contribute to these c
Autor:
Brian C. Schaefer, Maria Traver, Suman Paul, Michael A Washington, Joseph R. Latoche, Anuj K. Kashyap
Publikováno v:
Science Signaling. 7
Antigen-mediated stimulation of the T cell receptor (TCR) triggers activation of nuclear factor κB (NF-κB), a key transcriptional regulator of T cell proliferation and effector cell differentiation. TCR signaling to NF-κB requires both the Carma1-
Autor:
Natalia G. Cartwright, Clifton L. Dalgard, Gauthaman Sukumar, Joseph R. Latoche, Mouna Lagraoui, Brian C. Schaefer
Publikováno v:
Frontiers in Neurology, Vol 3 (2012)
Frontiers in Neurology
Frontiers in Neurology
An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major contributor to TBI-induced brain damage. However, much remains unknown regarding the induction a
Publikováno v:
Hearing research. 275(1-2)
Progressive sensorineural hearing loss in humans is a common and debilitating impairment. Sensorineural deafness in inbred strains of mice is a similarly common and genetically diverse phenotype providing experimental models to study the underlying g
Autor:
C. R. Srikumari Srisailapathy, Kausik Ray, Richard J.H. Smith, Konrad Noben-Trauth, Nikoletta Charizopoulou, Margit Schraders, Ronald J.C. Admiraal, Jeffrey R. Holt, Joseph R. Latoche, Arabandi Ramesh, Harold R. Neely, John K. Northup, Hannie Kremer, Andrea Lelli, Michael S. Hildebrand, Jaap Oostrik
Publikováno v:
Nature Communications
Nature Communications, 2, 201-201
Nature Communications, 2, pp. 201-201
Nature Communications, 2, 201-201
Nature Communications, 2, pp. 201-201
Sensorineural hearing loss affects the quality of life and communication of millions of people, but the underlying molecular mechanisms remain elusive. Here, we identify mutations in Gipc3 underlying progressive sensorineural hearing loss (age-relate
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11459 (2010)
Progressive sensorineural hearing loss is the most common form of acquired hearing impairment in the human population. It is also highly prevalent in inbred strains of mice, providing an experimental avenue to systematically map genetic risk factors
Externí odkaz:
https://doaj.org/article/ce68551087e64df68f4f4a8aa4a27250