Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph R. Knoedler"'
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-22 (2017)
Abstract Background Krüppel-like factor 9 (Klf9) is a zinc finger transcription factor that functions in neural cell differentiation, but little is known about its genomic targets or mechanism of action in neurons. Results We used the mouse hippocam
Externí odkaz:
https://doaj.org/article/edef5a617ec3409981c3eacb9a2b92f8
Autor:
Pia D Bagamasbad, Jose Ezekiel C Espina, Joseph R Knoedler, Arasakumar Subramani, Ariel J Harden, Robert J Denver
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220378 (2019)
The hippocampus is a well-known target of thyroid hormone (TH; e.g., 3,5,3'-triiodothyronine-T3) and glucocorticoid (GC; e.g., corticosterone-CORT) action. Despite evidence that TH and GC play critical roles in neural development and function, few st
Externí odkaz:
https://doaj.org/article/f4b30408d1ff4c958a514543e65d3806
Autor:
Kristen M. Berendzen, Ruchira Sharma, Maricruz Alvarado Mandujano, YiChao Wei, Forrest D. Rogers, Trenton C. Simmons, Adele H.M. Seelke, Jessica M. Bond, Rose D. Larios, Michael Sherman, Srinivas Parthasarathy, Isidero Espineda, Joseph R. Knoedler, Annaliese Beery, Karen L. Bales, Nirao M. Shah, Devanand S. Manoli
SummaryPrairie voles are among a small group of mammals that display long-term social attachment between mating partners. Many pharmacological studies show that signaling via the oxytocin receptor (OxtR) is critical for the display of social monogamy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d645a6f7bb0f7cc556f9b5f7b6ecf10
https://doi.org/10.1101/2022.07.22.501192
https://doi.org/10.1101/2022.07.22.501192
Autor:
Kristen M. Berendzen, Ruchira Sharma, Maricruz Alvarado Mandujano, Yichao Wei, Forrest D. Rogers, Trenton C. Simmons, Adele M.H. Seelke, Jessica M. Bond, Rose Larios, Nastacia L. Goodwin, Michael Sherman, Srinivas Parthasarthy, Isidero Espineda, Joseph R. Knoedler, Annaliese Beery, Karen L. Bales, Nirao M. Shah, Devanand S. Manoli
Publikováno v:
Neuron. 111:787-796.e4
Publikováno v:
J Biol Rhythms
An intricate transcription-translation feedback loop (TTFL) governs cellular circadian rhythms in mammals. Here, we report that the zinc finger transcription factor Krüppel-like factor 9 (KLF9) is regulated by this TTFL, it associates in chromatin a
Publikováno v:
Endocrinology
The clock protein period 1 (PER1) is a central component of the core transcription-translation feedback loop governing cell-autonomous circadian rhythms in animals. Transcription of Per1 is directly regulated by the glucocorticoid (GC) receptor (GR),
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-22 (2017)
BMC Genomics
BMC Genomics
Background Krüppel-like factor 9 (Klf9) is a zinc finger transcription factor that functions in neural cell differentiation, but little is known about its genomic targets or mechanism of action in neurons. Results We used the mouse hippocampus-deriv
Autor:
Joseph R. Knoedler, Nirao M. Shah
A long-standing goal in developmental neuroscience is to understand the mechanisms by which steroid sex hormones pattern the mammalian central nervous system along male or female pathways to enable subsequent displays of sexually dimorphic behaviors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb4f81c81ef4b84e3dfdac4b7fc4d06
https://europepmc.org/articles/PMC6347421/
https://europepmc.org/articles/PMC6347421/
Publikováno v:
Endocrinology. 157:1683-1693
Thyroid hormone (TH) receptor (TR)-β (trb) is induced by TH (autoinduced) in Xenopus tadpoles during metamorphosis. We previously showed that Krüppel-like factor 9 (Klf9) is rapidly induced by TH in the tadpole brain, associates in chromatin with t
Autor:
Joseph R. Knoedler, Renzhi Yang, Samantha R. Golf, Adarsh Tantry, Marc Tessier-Lavigne, Chung-ha Davis, Jun B. Ding, Shivani Thombare, Nirao M. Shah, Yichao Wei, Rachael L. Neve, Eliza L. Adams, Taehong Yang, Sayaka Inoue
Publikováno v:
Cell. 179:1393-1408.e16
Behaviors are inextricably linked to internal state. We have identified a neural mechanism that links female sexual behavior with the estrus, the ovulatory phase of the estrous cycle. We find that progesterone-receptor (PR)-expressing neurons in the