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pro vyhledávání: '"Joseph R. Holtman"'
Autor:
Joseph R. Holtman
Publikováno v:
Anesthesiology In-Training Exam Review ISBN: 9783030872656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e5269081baffbaea686b71a5789aa5
https://doi.org/10.1007/978-3-030-87266-3_37
https://doi.org/10.1007/978-3-030-87266-3_37
Autor:
Zohn Centimole, Terry A. Lennie, Melissa Thomas, Lynne A. Hall, Debra K. Moser, Vallire D. Hooper, Joseph R. Holtman, Carrell Rush, Jan Odom-Forren, Christian C. Apfel
Publikováno v:
Journal of PeriAnesthesia Nursing. 29:275-284
Purpose The purpose of this study is to determine patient management strategies and outcomes for self-care of postdischarge nausea and vomiting (PDNV). Design Prospective, comparative, descriptive, and longitudinal study. Methods The sample consisted
Autor:
Vallire D. Hooper, Debra K. Moser, Joseph R. Holtman, Christian C. Apfel, Lynne A. Hall, Terry A. Lennie, Leena Jalota, Jan Odom-Forren
Publikováno v:
Journal of Clinical Anesthesia. 25:551-559
1) To quantify the incidence and severity of postdischarge nausea and vomiting (PDNV) for 7 days in adults undergoing outpatient surgeries with general anesthesia; 2) to evaluate whether a risk model previously developed for the first two postoperati
Publikováno v:
Journal of Opioid Management. 9:85-96
Background: Opioids may cause progressive enhancement of pain sensitivity (opioid-induced hyperalgesia [OIH]) and thus, exacerbate existing pain. Animal studies also demonstrate paradoxical OIH with an ultralow dose (ULD, subanalgesic) of opioid; eg,
Autor:
J. Michael McIntosh, Cheryl Dowell, Peter A. Crooks, Linda P. Dwoskin, Joseph R. Holtman, Elzbieta P. Wala, Zhenfa Zhang
Publikováno v:
European Journal of Pharmacology. 670:500-508
Chronic pain is inadequately managed with currently available classes of analgesic drugs. Recently, peptide antagonists of the α9α10 nicotinic acetylcholine receptor were shown to be analgesic. The present study was conducted to characterize a nove
Publikováno v:
Journal of Opioid Management. 7:377-389
Background: In addition to producing analgesia, opioids can increase sensitivity to pain (opioid-induced hyperalgesia [OIH]) in humans and rodents. Tolerance/OIH is likely mediated by similar mechanisms that lead to development of hyperalgesia after
Autor:
Joseph R. Holtman, Elzbieta P. Wala
Publikováno v:
European Journal of Pharmacology. 651:89-95
In addition to analgesia opioids may also enhance pain sensitivity. Opioid-induced hyperalgesia, typically associated with potent mu-opioid agonists (e.g. fentanyl, morphine, and heroin), may be of clinical importance due to the possible counteractio
Publikováno v:
Pharmacology Biochemistry and Behavior. 94:352-362
Neuronal nicotinic acetylcholinic receptors (nAChR) are promising targets for the development of novel analgesics. Nicotine and other nAChR-agonists produce profound analgesia in rodent models of acute and persistent pain. However, significant side-e
Publikováno v:
Drug and Alcohol Dependence. 98:191-202
Abuse of prescription opioids has risen precipitously in the United States. Few controlled comparisons of the abuse liability of the most commonly abused opioids have been conducted. This outpatient study employed a double-blind, randomized, within-s
Autor:
Joseph R. Holtman, Elzbieta P. Wala
Publikováno v:
Pain. 114:62-70
The pain enhancing (hyperalgesic) effect of morphine was characterized in relation to pain stimulus (thermal, mechanical), dose, mode of administration (acute, chronic), sex and mechanism. We found that a low (subanalgesic) dose of morphine enhanced