Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph R. Guarini"'
Autor:
Jerry A. Weisbach, John R. E. Hoover, Joseph R. Guarini, Joseph V. Uri, George L. Dunn, Donald Pitkin, Ihor Zajac, Theodore J. Polansky, Henry F. Bartus, Lillian Phillips, Paul Actor
Publikováno v:
The Journal of Antibiotics. 32:1161-1167
Three cephalosporins with 7-(2-hydroxyiminophenylacetamido) side chains (SK&F 79433, 80000 and 80303), differing in their 3-substituents, exhibited similar broad-spectrum antibacterial activity in vitro against strains of Staphylococcus aureus, Strep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13074f7cd36dcd441bda7312a290224
https://doi.org/10.7164/antibiotics.32.1161
https://doi.org/10.7164/antibiotics.32.1161
Autor:
Jerry A. Weisbach, Joseph R. Guarini, Paul Actor, Joseph V. Uri, Donald Pitkin, Lillian Phillips, Robert M. DeMarinis
Publikováno v:
The Journal of Antibiotics. 31:82-91
Three semisynthetic cephamycin antibiotics (7alpha-methoxy-cephalosporins), SK&F 73678, SK&F 83088 (CS-1170) and cefoxitin, have been found to possess favorable biological and chemotherapeutic properties. All three cephamycins are active in vitro aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b680287ff0f6fbc4a4d6e62f6b021c8
https://doi.org/10.7164/antibiotics.31.82
https://doi.org/10.7164/antibiotics.31.82
Publikováno v:
The Journal of Antibiotics. 30:730-735
Cefazaflur has a broad-spectrum of in vitro antibacterial activity equal to or greater than that of the commercially-available cephalosporins. In addition, cefazaflur has activity against isolates of Enterobacter, Citrobacter and indole-positive Prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe51c86ca58196ff883e334eb9820dc
https://doi.org/10.7164/antibiotics.30.730
https://doi.org/10.7164/antibiotics.30.730
Publikováno v:
Chemotherapy. 22:313-318
The disc sensitivity and minimal inhibitory concentrations (MIC) of cefazolin and cephalothin were compared against a series of Escherichia coli isolates. These data were correlated with the mouse protective doses of the 2 cephalosporins in animals i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f73b9ef1f7f91825027e750240552db
https://doi.org/10.1159/000221938
https://doi.org/10.1159/000221938
Autor:
Jerry A. Weisbach, John F. Pauls, Paul Actor, Judith H. Dickson, Joseph R. Guarini, Joseph V. Uri
Publikováno v:
Antimicrobial Agents and Chemotherapy. 5:63-67
Cefazolin and cephalothin disk susceptibility and minimal inhibitory concentration determinations were conducted on 591 clinical isolates. Cefazolin demonstrated superior activity, as shown by lower minimal inhibitory concentrations, and a greater pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0aac3db7c6153e492ccf796de9da418
https://doi.org/10.1128/aac.5.1.63
https://doi.org/10.1128/aac.5.1.63
Laboratory studies with cefatrizine (SK + F 60771), a new broad-spectrum orally-active cephalosporin
Autor:
Carl S. Sachs, Joseph R. Guarini, David A. Berges, Paul Actor, George L. Dunn, Lillian Phillips, John R. E. Hoover, Joseph V. Uri, Jerry A. Weisbach, Ihor Zajac
Publikováno v:
The Journal of antibiotics. 28(8)
Cefatrizine (SK&F 60771), a new orally-active semisynthetic cephalosporin antibiotic with broad-spectrum antibacterial activity, was compared with cephalexin and cefazolin for in vitro and in vivo antibacterial activity and pharmacokinetic behavior i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9663038f83e6e76e3fcaf0b60a5b77
https://pubmed.ncbi.nlm.nih.gov/808525
https://pubmed.ncbi.nlm.nih.gov/808525
Publikováno v:
The Journal of antibiotics. 33(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3b4ff051a758720607f8ac72c04564
https://pubmed.ncbi.nlm.nih.gov/7372555
https://pubmed.ncbi.nlm.nih.gov/7372555
Autor:
Jerry A. Weisbach, Lillian Phillips, Ihor Zajac, Paul Actor, Robert M. DeMarinis, Joseph R. Guarini, Carl S. Sachs, John R. E. Hoover, Joseph V. Uri
Publikováno v:
The Journal of antibiotics. 28(6)
SK&F 59962, a new parenteral cephalosporin was found to have a high order of in vitro and in vivo antibacterial activity against a broad-spectrum of clinical isolates. When tested in vitro against gram-negative organisms, SK&F 59962 was consistently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d66fcd879f7a06a6356f00beac60b9c
https://pubmed.ncbi.nlm.nih.gov/238925
https://pubmed.ncbi.nlm.nih.gov/238925
Autor:
Jerry A. Weisbach, Donald Pitkin, David A. Berges, Joseph R. Guarini, George L. Dunn, Joseph V. Uri, John R. E. Hoover, Ihor Zajac, Lillian Phillips, Paul Actor
Publikováno v:
Antimicrobial agents and chemotherapy. 13(5)
SK&F 75073, a new parenteral cephalosporin, was found to have broad in vitro and in vivo antibacterial activity including isolates usually resistant to cephalothin and cefazolin. This activity included indole-positive Proteus and Enterobacter species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc205f8311acad71d43ef28fe5f2b5f
https://pubmed.ncbi.nlm.nih.gov/96734
https://pubmed.ncbi.nlm.nih.gov/96734
Autor:
Robert E. Chamberlain, Manford J. Robinson, Joseph V. Swintosky, Earl Rosen, Joseph R. Guarini
Publikováno v:
Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 45(1)
Quantitative studies were made on the effects of various additives such as procaine hydrochloride, dextrose, and citrate in reducing penicillin G procaine solubility in water. Aqueous vehicles were prepared in which the solubility was lowered to a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2cb2941f3cb3c2aae7397dc36182da
https://pubmed.ncbi.nlm.nih.gov/13278259
https://pubmed.ncbi.nlm.nih.gov/13278259