Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Joseph R. Garlich"'
Autor:
Donald L. Durden, Guillermo A. Morales, Joseph R. Garlich, Yuko Kono, Sadakatsu Ikeda, Jason K. Sicklick, Adam M. Burgoyne, Shweta Joshi, Alok R. Singh
SF1126 and Sorafenib inhibit cell cycle progression by inducing apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03307a9deb77b1c3ff83e6d4c494c1fe
https://doi.org/10.1158/1535-7163.22507045.v1
https://doi.org/10.1158/1535-7163.22507045.v1
Autor:
Donald L. Durden, Guillermo A. Morales, Joseph R. Garlich, Yuko Kono, Sadakatsu Ikeda, Jason K. Sicklick, Adam M. Burgoyne, Shweta Joshi, Alok R. Singh
Deregulated PI3K/AKT/mTOR, Ras/Raf/MAPK, and c-Myc signaling pathways are of prognostic significance in hepatocellular carcinoma (HCC). Sorafenib, the only drug clinically approved for patients with advanced HCC, blocks the Ras/Raf/MAPK pathway but i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e518a3ed05b07fda78e3134d0d6975
https://doi.org/10.1158/1535-7163.c.6538561.v1
https://doi.org/10.1158/1535-7163.c.6538561.v1
Autor:
Donald L. Durden, Joseph R. Garlich, Guillermo A. Morales, Christopher K. Glass, Hyun Bae Chun, Dylan Skola, Muamera Zulcic, Timothy V. Pham, Kevin X. Liu, Alok R. Singh, Shweta Joshi
File contains Supplementary Methods and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ed2e16625c34228c62d32c2d601d92
https://doi.org/10.1158/1535-7163.22506045
https://doi.org/10.1158/1535-7163.22506045
Autor:
Donald L. Durden, Guillermo A. Morales, Joseph R. Garlich, Yuko Kono, Sadakatsu Ikeda, Jason K. Sicklick, Adam M. Burgoyne, Shweta Joshi, Alok R. Singh
Contain description of Supplementary methods and legends to supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d7ac18bfdf39c38027d8e16b71000e
https://doi.org/10.1158/1535-7163.22507042
https://doi.org/10.1158/1535-7163.22507042
Autor:
Donald L. Durden, Joseph R. Garlich, Guillermo A. Morales, Christopher K. Glass, Hyun Bae Chun, Dylan Skola, Muamera Zulcic, Timothy V. Pham, Kevin X. Liu, Alok R. Singh, Shweta Joshi
Supplementary Fig. S1 shows JQ1 blocks IL4 induced CD206 expression. Supplementary Fig. S2 shows Differentially expressed genes in LPS-stimulated or IL4 stimulated BMDMs. Supplementary Fig. S3 shows Effect of JQ1 on LLC tumor growth. Supplementary Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adac5ed436b48495ac221a346a90f80
https://doi.org/10.1158/1535-7163.22506042
https://doi.org/10.1158/1535-7163.22506042
Autor:
Donald L. Durden, Guillermo A. Morales, Joseph R. Garlich, Yuko Kono, Sadakatsu Ikeda, Jason K. Sicklick, Adam M. Burgoyne, Shweta Joshi, Alok R. Singh
Chau Talalay Synergy studies on HCC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffa2adb3277e9f93c8f89eb7a21a132
https://doi.org/10.1158/1535-7163.22507039.v1
https://doi.org/10.1158/1535-7163.22507039.v1
Autor:
Donald L. Durden, Qiong Peng, H-K. Shu, Vikas Kundra, Gordon B. Mills, Yiling Lu, Ravoori Murali, Antoinette Miller, Xiaodong Peng, Jing Dong Su, Nandini Dey, Pradip De, Joseph R. Garlich
Supplementary Figures 1-5 from A Vascular Targeted Pan Phosphoinositide 3-Kinase Inhibitor Prodrug, SF1126, with Antitumor and Antiangiogenic Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e4c0eab5ec981bbc0a04120e38b2d1
https://doi.org/10.1158/0008-5472.22370132.v1
https://doi.org/10.1158/0008-5472.22370132.v1
Autor:
Donald L. Durden, Qiong Peng, H-K. Shu, Vikas Kundra, Gordon B. Mills, Yiling Lu, Ravoori Murali, Antoinette Miller, Xiaodong Peng, Jing Dong Su, Nandini Dey, Pradip De, Joseph R. Garlich
PTEN and the pan phosphoinositide 3-kinase (PI3K) inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1benzopyran-4-one (LY294002) exert significant control over tumor-induced angiogenesis and tumor growth in vivo. The LY294002 compound is not a viable drug cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057ccfeb406ff67f8fce6e923f77a9a4
https://doi.org/10.1158/0008-5472.c.6496280
https://doi.org/10.1158/0008-5472.c.6496280
Autor:
Alok R Singh, Shweta Joshi, Muamera Zulcic, Michael Alcaraz, Joseph R Garlich, Guillermo A Morales, Yoon J Cho, Lei Bao, Michael L Levy, Robert Newbury, Denise Malicki, Karen Messer, John Crawford, Donald L Durden
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150836 (2016)
Sonic hedgehog (SHH) medulloblastoma (MB) subtype is driven by a proliferative CD15+ tumor propagating cell (TPC), also considered in the literature as a putative cancer stem cell (CSC). Despite considerable research, much of the biology of this TPC
Externí odkaz:
https://doaj.org/article/ac04ecf6d2174fb5897dca31ed3b2a60
Autor:
Catherine C. Hedrick, Muamera Zulcic, Shweta Joshi, P. Dominick Sanders, Timothy V. Pham, Huy Q. Dinh, Daniel Shiang, Pablo Tamayo, Andrew B. Sharabi, Dylan Skola, Donald L. Durden, Kevin X. Liu, Guillermo A. Morales, Joseph R. Garlich, Christopher K. Glass, Alok R. Singh
Publikováno v:
Mol Cancer Ther
Macrophages (MΦ) play a critical role in tumor growth, immunosuppression, and inhibition of adaptive immune responses in cancer. Hence, targeting signaling pathways in MΦs that promote tumor immunosuppression will provide therapeutic benefit. PI3K