Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joseph R. Boyd"'
Autor:
Mahalia M. McGill, Alyssa R. Richman, Joseph R. Boyd, Bristy Sabikunnahar, Karolyn G. Lahue, Theresa L. Montgomery, Sydney Caldwell, Stella Varnum, Seth Frietze, Dimitry N. Krementsov
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system, representing the leading cause of non-traumatic neurologic disease in young adults. This disease is three times more common in women, yet more severe in men
Externí odkaz:
https://doaj.org/article/8a5232b7e72046b3ab0365eee456c24d
Autor:
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis. The HHV-6A/B genomes have been shown to be present in an integrated state in the te
Externí odkaz:
https://doaj.org/article/fa0d6b7dc55448a197de80e013354e60
Publikováno v:
Epigenomes, Vol 3, Iss 2, p 11 (2019)
The spreading of epigenetic domains has emerged as a distinguishing epigenomic phenotype for diverse cell types. In particular, clusters of H3K27ac- and H3K4me3-marked elements, referred to as super-enhancers, and broad H3K4me3 domains, respectively,
Externí odkaz:
https://doaj.org/article/0ea3879ba5e94c27b338ba3e3a2322b2
Autor:
Joseph R Boyd, Cong Gao, Kathleen Quinn, Andrew Fritz, Janet Stein, Gary Stein, Karen Glass, Seth Frietze
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Epigenomic profiling assays such as ChIP-seq have been widely used to map the genome-wide enrichment profiles of chromatin-associated proteins and posttranslational histone modifications. Sequencing depth is a key parameter in exp
Externí odkaz:
https://doaj.org/article/0333a297046742b194cae391f7e0eb4b
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
BMC Research Notes
BMC Research Notes
Objective Among the different methods to profile the genome-wide patterns of transcription factor binding and histone modifications in cells and tissues, CUT&RUN has emerged as a more efficient approach that allows for a higher signal-to-noise ratio
Autor:
Prachi N. Ghule, Joseph R. Boyd, Fleur Kabala, Andrew J. Fritz, Nicole A. Bouffard, Cong Gao, Kathleen Bright, Jill Macfarlane, David J. Seward, Gianluca Pegoraro, Tom Misteli, Jane B. Lian, Seth Frietze, Janet L. Stein, Andre J. van Wijnen, Gary S. Stein
Publikováno v:
Gene. 873:147469
Autor:
Jane B. Lian, Jonathan A. R. Gordon, Nicole A. Bouffard, John H. Bushweller, Andrew J. Fritz, Joseph R. Boyd, Sayyed K. Zaidi, Gary S. Stein, Janet L. Stein, Anuradha Illendula, Joshua T. Rose, Eliana Moskovitz
Publikováno v:
Oncotarget
RUNX1 has recently been shown to play an important role in determination of mammary epithelial cell identity. However, mechanisms by which loss of the RUNX1 transcription factor in mammary epithelial cells leads to epithelial-to-mesenchymal transitio
Autor:
Jane B. Lian, Jason Kost, Joseph R. Boyd, Mark Fitzgerald, Seth Frietze, Deli Hong, Alqassem Abuarqoub, Prachi N. Ghule, Miles Malik, Janet L. Stein, John H. Bushweller, Sayyed K. Zaidi, Andrew J. Fritz, Jonathan A. R. Gordon, Sebastian Hanna, Kristiaan H. Finstaad, Gary S. Stein, Coralee E. Tye
Publikováno v:
J Cell Physiol
Breast cancer stem cells (BCSCs) are competent to initiate tumor formation and growth and refractory to conventional therapies. Consequently BCSCs are implicated in tumor recurrence. Many signaling cascades associated with BCSCs are critical for epit
Autor:
Joseph R. Boyd, Mahalia M. McGill, Karolyn G. Lahue, Theresa L. Montgomery, Seth Frietze, Sydney Caldwell, Dimitry N. Krementsov, Bristy Sabikunnahar, Stella Varnum, Alyssa R. Richman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system, representing the leading cause of non-traumatic neurologic disease in young adults. This disease is three times more common in women, yet more severe in men
Autor:
Karen C. Glass, Kathleen Quinn, Hana Paculova, Joseph R. Boyd, Samuel P. Boyson, Seth Frietze, Cong Gao
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3606, p 3606 (2021)
Cancers, Vol 13, Iss 3606, p 3606 (2021)
Simple Summary This review provides an in depth analysis of the role of bromodomain-containing proteins in cancer development. As readers of acetylated lysine on nucleosomal histones, bromodomain proteins are poised to activate gene expression, and o