Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Joseph R Bianchine"'
Autor:
Joseph R. Bianchine, H. McConnell
Scientists have speculated as to the nature of cerebrospinal fluid (CSF) -'the third circulation'or'vital spirit'for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an'animal sp
Publikováno v:
Scopus-Elsevier
Didanosine (ddI) is currently used in the management of patients infected by the human immunodeficiency virus. Rifabutin (RBT) is being extensively used for prophylaxis against Mycobacterium avium complex (MAC) infections. Due to its acid-labile char
Autor:
Sandra M. Swain, Fredrick S. Whaley, Joseph R. Bianchine, Miriam C. Gerber, Richard A. Gams, Michael S. Ewer
Publikováno v:
Journal of Clinical Oncology. 15:1333-1340
PURPOSE To assess whether dexrazoxane (DZR) given after a cumulative doxorubicin dose of 300 mg/m2 confers cardioprotection in patients with advanced breast cancer treated with fluorouracil, doxorubicin, and cyclophosphamide (FAC). PATIENTS AND METHO
Autor:
Enrique Velez-Garcia, Richard A. Gams, Darcy V. Spicer, Ajit Desai, Sandra M. Swain, Joseph R. Bianchine, James L. Speyer, Steven Weisberg, Abraham Mittelman, Fredrick S. Whaley, Martin York, Stephen E. Jones, Scott Wadler, Kelly Pendergrass, Sandeep K. Reddy, Miriam C. Gerber, Charles L. Vogel, Michael S. Ewer
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
PURPOSE To determine the cardioprotective effect of dexrazoxane (DZR) used in a doxorubicin-based combination therapy in advanced breast cancer. PATIENTS AND METHODS Between November 1988 and January 1991, 534 patients with advanced breast cancer wer
Publikováno v:
Clinical pharmacology and therapeutics. 52(4)
The relative bioavailability of the capsule dose form (150 mg) and the effect of high-fat food were assessed in a randomized, three-way crossover trial of rifabutin in 12 healthy male volunteers. Each subject received a single 150 mg dose as a soluti
Autor:
James P. Lavelle, Prem K. Narang, Joseph R. Bianchine, Carol Braun Trapnell, John R. Schoenfelder
Publikováno v:
New England Journal of Medicine. 330:1316-1317
To the Editor: The results of two double-blind, randomized, placebo-controlled trials published in the Journal (Sept. 16 issue)1 have shown that prophylactic treatment with rifabutin (300 mg per day) significantly reduces the incidence of Mycobacteri
Publikováno v:
Psychopharmacology. 78:317-321
The effect of prostaglandins (PG) on amphetamine(AMPH)-induced circling was examined in mice unilaterally lesioned with 6-hydroxy-dopamine. At doses of 0.03-1.0 nmol/g, intraventricularly injected PGD2, PGE2, and PGF2 alpha all inhibited AMP-induced
Autor:
W. Gordon Walker, Thomas M. Twomey, Andrew Whelton, M. Schach von Wittenau, Joseph R. Bianchine
Publikováno v:
Kidney International. 5(5):365-371
Doxycycline pharmacokinetics in the absence of renal function. Doxycycline is a new tetracycline that is now in widespread clinical use. It differs from the other tetracycline drugs in many important respects including small daily dosage schedules, e
Publikováno v:
Clinical Pharmacology and Therapeutics. 32:247-252
A study to compare the effects of three piroxicam regimens and aspirin on fecal blood loss (FBL) was conducted among 39 healthy men. Fourteen of the subjects also underwent prestudy and poststudy gastroscopy. There was an increase in FBL after aspiri
Publikováno v:
American Journal of Hematology. 11:233-240
Reactive oxygen species, probably hydroxyl radicals (OH.), have been suggested to be generated during arachidonic acid (AA) metabolism and, once released, these species can modify the rate and extent of various reactions involved in AA metabolism. We