Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Joseph Paquet"'
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Akademický článek
Enzyme-controlled, nutritive hydrogel for mesenchymal stromal cell survival and paracrine functions
Autor: Cyprien Denoeud, Guotian Luo, Joseph Paquet, Julie Boisselier, Pauline Wosinski, Adrien Moya, Ahmad Diallo, Nathanael Larochette, Stéphane Marinesco, Anne Meiller, Pierre Becquart, Hilel Moussi, Jean-Thomas Vilquin, Delphine Logeart-Avramoglou, Adeline Gand, Véronique Larreta-Garde, Emmanuel Pauthe, Esther Potier, Hervé Petite
Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Culture-adapted human mesenchymal stromal cells (hMSCs) are appealing candidates for regenerative medicine applications. However, these cells implanted in lesions as single cells or tissue constructs encounter an ischemic microenvironment re
Externí odkaz: https://doaj.org/article/9f58b505416f479fac0e002e4cdcf8c2
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2
Akademický článek
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation
Autor: Rachael Miller, Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato, Nozomi Yamada, Julia Alterman, Dimas Echeveria, Ken Yamada, Jonathan Watts, Christelle Anaclet, Marian DiFiglia, Anastasia Khvorova, Neil Aronin
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102359- (2024)
Oligonucleotide therapeutics (ASOs and siRNAs) have been explored for modulation of gene expression in the central nervous system (CNS), with several drugs approved and many in clinical evaluation. Administration of highly concentrated oligonucleotid
Externí odkaz: https://doaj.org/article/7a3e9e86c8024f13a243cc537165a446
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3
Human Mesenchymal Stem Cell Failure to Adapt to Glucose Shortage and Rapidly Use Intracellular Energy Reserves Through Glycolysis Explains Poor Cell Survival After Implantation
Autor: Karim Oudina, Nathanaël Larochette, Adrien Moya, Mickael Deschepper, Joseph Paquet, Cyprien Denoeud, Hervé Petite, Morad Bensidhoum, Delphine Logeart-Avramoglou
Publikováno v: STEM CELLS
STEM CELLS, AlphaMed Press, 2018, 36 (3), pp.363-376. ⟨10.1002/stem.2763⟩
Mesenchymal stem cells (MSCs) hold considerable promise in tissue engineering (TE). However, their poor survival when exogenously administered limits their therapeutic potential. Previous studies from our group demonstrated that lack of glucose (glc)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829793dee3933849f8f1b794872e21ca
https://doi.org/10.1002/stem.2763
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4
Type 2 diabetes alters mesenchymal stem cell secretome composition and angiogenic properties
Autor: Guavri Caliaperoumal, Jonathan Ribot, Fani Anagnostou, Catherine Boisson-Vidal, Joseph Paquet, Hervé Petite
Publikováno v: Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2017, 21 (2), pp.349-363. ⟨10.1111/jcmm.12969⟩
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2017, 21 (2), pp.349-363. 〈10.1111/jcmm.12969〉
Journal of Cellular and Molecular Medicine, 2017, 21 (2), pp.349-363. ⟨10.1111/jcmm.12969⟩
International audience; This study aimed at characterizing the impact of type 2 diabetes mellitus (T2DM) on the bone marrow mesenchymal stem cell (BMMSC) secre-tome and angiogenic properties. BMMSCs from Zucker diabetic fatty rats (ZDF) (a T2DM model
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2886f5ef42f622c28e46ea9994a55fc
https://doi.org/10.1111/jcmm.12969
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5
Comparison of Survival and Osteogenic Ability of Human Mesenchymal Stem Cells in Orthotopic and Ectopic Sites in Mice
Autor: Delphine Logeart-Avramoglou, Hervé Petite, Mathieu Manassero, Jose Retortillo, Véronique Viateau, Morad Bensidhoum, Mickael Deschepper, Joseph Paquet
Publikováno v: Tissue Engineering: Parts A, B, and C
Tissue Engineering: Parts A, B, and C, Mary Ann Liebert, 2016, 22 (5-6), pp.534-544. ⟨10.1089/ten.TEA.2015.0346⟩
Tissue constructs containing mesenchymal stem cells (MSCs) are appealing strategies for repairing large segmental bone defects, but they do not allow consistent bone healing and early cell death was identified as a cause of failure. However, little i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72a51c407402b7c97abee2a8a13c890
https://doi.org/10.1089/ten.tea.2015.0346
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6
The paracrine effects of human induced pluripotent stem cells promote bone-like structures via the upregulation of BMP expression in a mouse ectopic model
Autor: Hervé Petite, Karim Oudina, Nathanael Larochette, Christian Pinset, Mickael Deschepper, Emmanuelle Massouridès, Morad Bensidhoum, Joseph Paquet, Adrien Moya
Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Use of human induced pluripotent stem cells (h-iPSCs) for bone tissue engineering is most appealing, because h-iPSCs are an inexhaustible source of osteocompetent cells. The present study investigated the contribution of undifferentiated h-iPSCs and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3cab5ee78a3bd059be167776f6afc3
http://europepmc.org/articles/PMC6244408
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7
In Vivo Tissue Engineering of Human Airways
Autor: Hervé Petite, Morad Bensidhoum, Dana M. Radu, Hervé Dutau, Yurdagul Uzunhan, Emmanuel Martinod, Sébastien Abad, Joseph Paquet, Eric Vicaut
Publikováno v: The Annals of thoracic surgery. 103(5)
Background Airway transplantation remains a major challenge in thoracic surgery. Based on our previous laboratory work, we developed the techniques required to bioengineer a tracheal substitute in vivo using cryopreserved aortic allografts as biologi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f04b115c8431cd3fc3dd96332a7300
https://pubmed.ncbi.nlm.nih.gov/28109571
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8
la tension d'oxygène régule les fonctions paracrines des cellules souches mésenchymateuses
Autor: Joseph, Paquet, Mickael, Deschepper, Adrien, Moya, Delphine, Logeart-Avramoglou, Catherine, Boisson-Vidal, Hervé, Petite
Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Wiley, 2015, 4 (7), pp.809-821. ⟨10.5966/sctm.2014-0180⟩
International audience; Mesenchymal stem cells (MSCs) have captured the attention and research endeavors of the scientific world because of their differentiation potential. However, there is accumulating evidence suggesting that the beneficial effect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59f1a5b62623e716d0e7841fc3b0bfbe
https://www.hal.inserm.fr/inserm-01973949
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9
Des biomatériaux à l'ingénierie tissulaire : perspectives en réparation osseuse
Autor: Joseph Paquet, Adrien Moya, Hervé Petite, Mathieu Manassero, M. Bensidhoum, Mickael Deschepper
Publikováno v: Technologies biomédicales.
Les pertes de substance, surtout lorsqu'elles sont de grande taille, mettent souvent a mal les capacites naturelles de reparation de l'os. Alors que le traitement de reference repose sur l'apport d'os autologue, les chirurgiens peuvent etre amenes a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::810a0bf02d3d7da283d64df6014cd046
https://doi.org/10.51257/a-v1-med7200
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