Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joseph P.M. Blair"'
Autor:
Cecilie L. Bager, M. H. Tang, Anne-Christine Bay-Jensen, Søren Brunak, P. Frederiksen, Morten A. Karsdal, Joseph P.M. Blair
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Scientific Reports
Blair, J P M, Bay-Jensen, A-C, Tang, M H, Frederiksen, P, Bager, C, Karsdal, M & Brunak, S 2020, ' Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis ', Scientific Reports, vol. 10, no. 1, 13975 . https://doi.org/10.1038/s41598-020-70942-x
Rheumatoid arthritis (RA) is a chronic inflammatory disease with fluctuating course of progression. Despite substantial improvement in treatments in recent years, treatment response is still not guaranteed. The aim of this study was to identify varia
Autor:
Ruth Tal-Singer, Diana Julie Leeming, Joseph P.M. Blair, Jørgen Vestbo, Jannie M.B. Sand, Morten A. Karsdal, Sarah Rønnow, Bruce E. Miller
Publikováno v:
Monitoring airway disease.
Autor:
Kim Henriksen, Anne-Christine Bay-Jensen, Joseph P.M. Blair, Cecilie L. Bager, Morten A. Karsdal, Claus Christiansen, Man-Hung Eric Tang
Publikováno v:
Neurology: Genetics
article-version (Version of Record) 3
Tang, M-H E, Blair, J P M, Bager, C L, Bay-Jensen, A-C, Henriksen, K, Christiansen, C & Karsdal, M A 2020, ' Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia ', Neurology: Genetics, vol. 6, no. 5, 508 . https://doi.org/10.1212/NXG.0000000000000508
article-version (Version of Record) 3
Tang, M-H E, Blair, J P M, Bager, C L, Bay-Jensen, A-C, Henriksen, K, Christiansen, C & Karsdal, M A 2020, ' Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia ', Neurology: Genetics, vol. 6, no. 5, 508 . https://doi.org/10.1212/NXG.0000000000000508
ObjectiveDysregulation of type I collagen metabolism has a great impact on human health. We have previously seen that matrix metalloproteinase–degraded type I collagen (C1M) is associated with early death and age-related pathologies. To dissect the
Autor:
Henning B. Nielsen, Marie S. Worm, Joseph P.M. Blair, Bente Juel Riis, Cecilie L. Bager, Niels H. Secher, Claus Christiansen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Worm, M S, Bager, C L, Blair, J P M, Secher, N H, Riis, B J, Christiansen, C & Nielsen, H B 2020, ' Atrial fibrillation is associated with lean body mass in postmenopausal women ', Scientific Reports, vol. 10, no. 1, 573 . https://doi.org/10.1038/s41598-019-57167-3
Scientific Reports
Worm, M S, Bager, C L, Blair, J P M, Secher, N H, Riis, B J, Christiansen, C & Nielsen, H B 2020, ' Atrial fibrillation is associated with lean body mass in postmenopausal women ', Scientific Reports, vol. 10, no. 1, 573 . https://doi.org/10.1038/s41598-019-57167-3
Scientific Reports
This study investigated the association between body composition and risk of atrial fibrillation (AF) in postmenopausal women. In a retrospective analysis we assessed data from 5704 postmenopausal women (age 70.7 ± 6.5 yrs.) who in 1999–2001 parti
Autor:
Anne-Christine Bay-Jensen, Sven Lindemann, Signe Holm Nielsen, Solveig Skovlund Groen, Dovile Sinkeviciute, Patrik Önnerfjord, Christian S. Thudium, Simon Francis Thomsen, Lars Arendt-Nielsen, Morten A. Karsdal, Line Mærsk Staunstrup, Joseph P.M. Blair, Daniela Werkmann
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 4, Pp 100207-(2021)
Objectives: There is an unmet medical need for biomarkers in OA which can be applied in clinical drug development trials. The present study describes the development of a specific and robust assay measuring type II collagen degradation (T2CM) and dis
Autor:
Adam Platt, Joseph P.M. Blair, Cecilie L. Bager, Morten A. Karsdal, Anne-Christine Bay-Jensen
Publikováno v:
PLoS ONE
Blair, J P M, Bager, C, Platt, A, Karsdal, M & Bay-Jensen, A-C 2019, ' Identification of pathological RA endotypes using blood-based biomarkers reflecting tissue metabolism. A retrospective and explorative analysis of two phase III RA studies ', PLoS ONE, vol. 14, no. 7, e0219980 . https://doi.org/10.1371/journal.pone.0219980
PLoS ONE, Vol 14, Iss 7, p e0219980 (2019)
Blair, J P M, Bager, C, Platt, A, Karsdal, M & Bay-Jensen, A-C 2019, ' Identification of pathological RA endotypes using blood-based biomarkers reflecting tissue metabolism. A retrospective and explorative analysis of two phase III RA studies ', PLoS ONE, vol. 14, no. 7, e0219980 . https://doi.org/10.1371/journal.pone.0219980
PLoS ONE, Vol 14, Iss 7, p e0219980 (2019)
There is an increasing demand for accurate endotyping of patients according to their pathogenesis to allow more targeted treatment. We explore a combination of blood-based joint tissue metabolites (neoepitopes) to enable patient clustering through di
Autor:
Henning B. Nielsen, Jesper Christensen, Joseph P.M. Blair, Cecilie L. Bager, Morten A. Karsdal, Line Mærsk Staunstrup, Bente Klarlund Pedersen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Staunstrup, L M, Nielsen, H B, Pedersen, B K, Karsdal, M, Blair, J P M, Christensen, J F & Bager, C L 2019, ' Cancer risk in relation to body fat distribution, evaluated by DXA-scans, in postmenopausal women – the Prospective Epidemiological Risk Factor (PERF) study ', Scientific Reports, vol. 9, no. 1, 5379 . https://doi.org/10.1038/s41598-019-41550-1
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Staunstrup, L M, Nielsen, H B, Pedersen, B K, Karsdal, M, Blair, J P M, Christensen, J F & Bager, C L 2019, ' Cancer risk in relation to body fat distribution, evaluated by DXA-scans, in postmenopausal women – the Prospective Epidemiological Risk Factor (PERF) study ', Scientific Reports, vol. 9, no. 1, 5379 . https://doi.org/10.1038/s41598-019-41550-1
Studies with direct measures of body fat distribution are required to explore the association between central and general obesity to cancer risk in postmenopausal women. This study investigates the association between central obesity and general obes
Autor:
S. F. Madsen, Mette Østergaard, Inge Juul Sørensen, Joseph P.M. Blair, S. Holm Nielsen, M.A. Karsdal, Lone Morsel-Carlsen, S. Juhl Pedersen, H. Port, S. Seven, A.-C. Bay-Jensen
Publikováno v:
Annals of the Rheumatic Diseases. 80:742.1-742
Background:Axial spondyloarthritis (axSpA) is a common chronic inflammatory disease, associated with extracellular matrix (ECM) remodeling of the cartilage, bone and connective tissues. The primary symptom of axSpA is back pain, caused by inflammatio
Autor:
Joseph P.M. Blair, M.A. Karsdal, Cecilie L. Bager, Michael E. Weinblatt, A.-C. Bay-Jensen, Adam Platt
Publikováno v:
Rheumatoid arthritis – prognosis, predictors and outcome.
Publikováno v:
Osteoarthritis and Cartilage. 27:S105-S106