Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Joseph P. Walton"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Tinnitus is the phantom perception of sound that has no external source. A neurological signature of tinnitus, and the frequently associated hyperacusis, is an imbalance between excitatory and inhibitory activity in the central auditory system (CAS),
Externí odkaz:
https://doaj.org/article/0f63544f12704db1aac11bf3932d80c5
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101166- (2021)
The acoustic startle response (ASR) is an involuntary muscle reflex that occurs in response to a transient loud sound and is a highly-utilized method of assessing hearing status in animal models. Currently, a high level of variability exists in the r
Externí odkaz:
https://doaj.org/article/ad0ee4713f1543fe9bcb4e8fa1104448
Autor:
Farzad Forouzandeh, Nuzhet N. Ahamed, Xiaoxia Zhu, Parveen Bazard, Krittika Goyal, Joseph P. Walton, Robert D. Frisina, David A. Borkholder
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 538 (2021)
Here we present a 3D-printed, wirelessly controlled microsystem for drug delivery, comprising a refillable microreservoir and a phase-change peristaltic micropump. The micropump structure was inkjet-printed on the back of a printed circuit board arou
Externí odkaz:
https://doaj.org/article/980c98f37bfc45d3870bf95341520557
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract There is a compelling need for the development of new sensory and neural prosthetic devices which are capable of more precise point stimulation. Current prosthetic devices suffer from the limitation of low spatial resolution due to the non-s
Externí odkaz:
https://doaj.org/article/c82512d0dadf4cc7a84ca2147062d172
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Active mechanical amplification of sound occurs in cochlear outer hair cells (OHCs) that change their length with oscillations of their membrane potential. Such length changes are the proposed cellular source of the cochlear amplifier, and prestin is
Externí odkaz:
https://doaj.org/article/0ac90b7f62554316a0fccacdfce67b7b
Autor:
Farzad Forouzandeh, Nuzhet N. Ahamed, Meng-Chun Hsu, Joseph P. Walton, Robert D. Frisina, David A. Borkholder
Publikováno v:
Micromachines, Vol 11, Iss 7, p 648 (2020)
Reservoir-based drug delivery microsystems have enabled novel and effective drug delivery concepts in recent decades. These systems typically comprise integrated storing and pumping components. Here we present a stand-alone, modular, thin, scalable,
Externí odkaz:
https://doaj.org/article/d061f8a88d614c2bbdb1d6962ef85299
Autor:
Timothy J. Fawcett, Ryan J. Longenecker, Dimitri L. Brunelle, Joel I. Berger, Mark N. Wallace, Alex V. Galazyuk, Merri J. Rosen, Richard J. Salvi, Joseph P. Walton
Publikováno v:
Hearing research. 428
The startle reflex (SR), a robust, motor response elicited by an intense auditory, visual, or somatosensory stimulus has been widely used as a tool to assess psychophysiology in humans and animals for almost a century in diverse fields such as schizo
Autor:
Robert D. Frisina, Nathan D. Cahill, David A. Borkholder, Sanketh S. Moudgalya, Kevin J. Wilson, Xiaoxia Zhu, Mikalai M. Budzevich, Joseph P. Walton
Publikováno v:
Hearing Research. 380:46-59
Inner ear disorders such as sensorineural deafness and genetic diseases may one day be treated with local drug delivery to the inner ear. Current pharmacokinetic models have been based on invasive methods to measure drug concentrations, limiting them
Publikováno v:
eNeuro
Congenital sensorineural hearing loss (SNHL) affects thousands of infants each year and results in significant delays in speech and language development. Previous studies have shown that early exposure to a simple augmented acoustic environment (AAE)
Publikováno v:
Neurobiology of aging. 110
Recent evidence suggests that modulation of the large-conductance, calcium-activated potassium (BK) channel regulates auditory processing in the brain. Because ion channel expression often changes during aging, this could be a factor in age-related h