Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joseph P. Torella"'
Autor:
Janice S. Chen, Brendan Colón, Brendon Dusel, Marika Ziesack, Jeffrey C. Way, Joseph P. Torella
Publikováno v:
PeerJ, Vol 3, p e1468 (2015)
Ralstonia eutropha H16 is a facultatively autotrophic hydrogen-oxidizing bacterium capable of producing polyhydroxybutyrate (PHB)-based bioplastics. As PHB’s physical properties may be improved by incorporation of medium-chain-length fatty acids (M
Externí odkaz:
https://doaj.org/article/3030a1ff9c234554abdb097000cdfa69
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 6, p e1000796 (2010)
The rapid proliferation of antibiotic-resistant pathogens has spurred the use of drug combinations to maintain clinical efficacy and combat the evolution of resistance. Drug pairs can interact synergistically or antagonistically, yielding inhibitory
Externí odkaz:
https://doaj.org/article/723f36d16d8c46fab7357174c30bad8b
Autor:
Joseph P. Torella, Christian R. Boehm, Jan-Hung Chen, Jeffrey C. Way, Florian Lienert, Pamela A. Silver
Publikováno v:
Nature Protocols. 9:2075-2089
Recombination-based DNA construction methods, such as Gibson assembly, have made it possible to easily and simultaneously assemble multiple DNA parts, and they hold promise for the development and optimization of metabolic pathways and functional gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd916f19f6aaab6d8af1dd5ea7d5e2b2
https://doi.org/10.1038/nprot.2014.145
https://doi.org/10.1038/nprot.2014.145
Autor:
Jan-Hung Chen, Christian R. Boehm, Florian Lienert, Pamela A. Silver, Joseph P. Torella, Jeffrey C. Way
Publikováno v:
Nucleic Acids Research
In vitro recombination methods have enabled one-step construction of large DNA sequences from multiple parts. Although synthetic biological circuits can in principle be assembled in the same fashion, they typically contain repeated sequence elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c24d2a935e4554d431fb262dfcfa6c0
https://doi.org/10.1093/nar/gkt860
https://doi.org/10.1093/nar/gkt860
Autor:
Jan-Hung Chen, Joseph P. Torella, Ryan R. Richardson, Pamela A. Silver, Michael W. Norsworthy, Florian Lienert
Publikováno v:
Nucleic Acids Research
Biological computing circuits can enhance our ability to control cellular functions and have potential applications in tissue engineering and medical treatments. Transcriptional activator-like effectors (TALEs) represent attractive components of synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d250c7e1fcf06f5f4a1bd85ec79f00
http://europepmc.org/articles/PMC3834826
http://europepmc.org/articles/PMC3834826
Autor:
Tyler J. Ford, Amanda M. Chen, Joseph P. Torella, Scott N. Kim, Jeffrey C. Way, Pamela A. Silver
Publikováno v:
Proceedings of the National Academy of Sciences. 110:11290-11295
Medium-chain fatty acids (MCFAs, 4–12 carbons) are valuable as precursors to industrial chemicals and biofuels, but are not canonical products of microbial fatty acid synthesis. We engineered microbial production of the full range of even- and odd-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf0db7dfdd571225f4d420e145c2727
https://doi.org/10.1073/pnas.1307129110
https://doi.org/10.1073/pnas.1307129110
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40207 (2012)
PLoS ONE; Vol 7
PLoS ONE, Vol 7, Iss 7, p e40207 (2012)
PLoS ONE; Vol 7
Many nucleic acid polymerases function in clusters known as factories. We investigate whether the RNA polymerase (RNAP) of phage T7 also clusters when active. Using 'pulldowns' and fluorescence correlation spectroscopy we find that elongation complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1388d5e8caa6118ce520afdd610bf4
https://doi.org/10.1371/journal.pone.0040207
https://doi.org/10.1371/journal.pone.0040207
Autor:
Mike Heilemann, Ling Chin Hwang, Seamus Holden, Robert Crawford, Konstantinos Lymperopoulos, Achillefs N. Kapanidis, Joseph P. Torella
Publikováno v:
Angewandte Chemie. 122:1338-1342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48fe24f0d524bf9504bb044a4e36862
https://doi.org/10.1002/ange.200904597
https://doi.org/10.1002/ange.200904597
Publikováno v:
ChemPhysChem
ChemPhysChem; Vol 11
ChemPhysChem; Vol 11
Probability distribution analysis (PDA) is a recently developed statistical tool for predicting the shapes of single-molecule fluorescence resonance energy transfer (smFRET) histograms, which allows the identification of single or multiple static mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617c002e580c1696df2595c7be15f275
Autor:
Konstantinos Lymperopoulos, Mike Heilemann, Achillefs N. Kapanidis, Joseph P. Torella, Seamus Holden, Robert Crawford, Ling Chin Hwang
Publikováno v:
Angewandte Chemie International Edition; Vol 49
Angewandte Chemie International Edition
Angewandte Chemie International Edition
Transcription factors (TFs) are sequence-specific DNA-binding proteins that control much of gene expression. TFs are natural biosensors and switches, translating chemical and physical signals (temperature shifts, light exposure, chemical concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096e799eac2a47f29197c4c17835f166