Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Joseph P. Marino"'
Autor:
Pieter H.E. Groot, Nigel J. Pearce, John W. Yates, Claire Stocker, Charles Sauermelch, Christopher P. Doe, Robert N. Willette, Alan Olzinski, Tambra Peters, Denise d'Epagnier, Kathleen O. Morasco, John A. Krawiec, Christine L. Webb, Karpagam Aravindhan, Beat Jucker, Mark Burgert, Chun Ma, Joseph P. Marino, Jon L. Collins, Colin H. Macphee, Scott K. Thompson, Michael Jaye
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 10, Pp 2182-2191 (2005)
Liver X receptor (LXR) nuclear receptors regulate the expression of genes involved in whole body cholesterol trafficking, including absorption, excretion, catabolism, and cellular efflux, and possess both anti-inflammatory and antidiabetic actions. A
Externí odkaz:
https://doaj.org/article/a93b77eb6ebb42eda0f367c3bb33cfa8
Publikováno v:
Frontiers in Sports and Active Living, Vol 5 (2023)
Externí odkaz:
https://doaj.org/article/f57346fdf88e41e8be108890a60d4877
Autor:
Nicole L. Stott Bond, Didier Dréau, Ian Marriott, Jeanette M. Bennett, Michael J. Turner, Susan T. Arthur, Joseph S. Marino
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 65 (2022)
Lung cancer maintains a relatively small survival rate (~19%) over a 5-year period and up to 80–85% of all lung cancer diagnoses are Non-Small Cell Lung Cancer (NSCLC). To determine whether metformin reduces non-small cell lung cancer (NSCLC) LL/2
Externí odkaz:
https://doaj.org/article/6d5145733d434748a11f6f760b09eeba
Publikováno v:
Biology, Vol 9, Iss 6, p 115 (2020)
The role of Notch signaling is widely studied in skeletal muscle regeneration but little is known about its influences on muscle protein synthesis (MPS). The purpose of this study was to investigate whether Notch signaling is involved in the regulati
Externí odkaz:
https://doaj.org/article/4846b090f4e4439db41bcebfac387c21
Publikováno v:
Journal of Health Economics and Outcomes Research, Vol 5, Iss 2 (2017)
**Objective:** Chronic obstructive pulmonary disease (COPD) is highly prevalent in the elderly population and typically reduces overall quality of life. Exacerbations of COPD are commonly treated with corticosteroids, a class of drug known to cause i
Externí odkaz:
https://doaj.org/article/0db86ea10c334c6ba2be3799ecb341ec
Autor:
Paolo A. Centrella, Peng Li, G Joseph Franklin, Svetlana L. Belyanskaya, Joseph P. Marino, Steven R. Skinner, Barry A. Morgan, Matthew A. Clark, Jason W. Dodson, Jeffrey A. Messer, Yun Ding, Jennifer L. DeLorey, David I. Israel
Publikováno v:
Bioorganicmedicinal chemistry. 41
Inhibition of soluble epoxide hydrolase (sEH) has recently emerged as a new approach to treat cardiovascular disease and respiratory disease. Inhibitors based on 1,3,5-triazine chemotype were discovered through affinity selection against two triazine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ef26aa0ff6dd53c73f4758004748fd
https://pubmed.ncbi.nlm.nih.gov/34023664
https://pubmed.ncbi.nlm.nih.gov/34023664
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79849 (2013)
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age women. The syndrome is caused by a combination of environmental influences and genetic predisposition. Despite extensive efforts, the heritable factors contrib
Externí odkaz:
https://doaj.org/article/44bd5d4ae60c428ea61c201c26abf4d4
Autor:
Christopher L Dearth, Qingnian Goh, Joseph S Marino, Peter A Cicinelli, Maria J Torres-Palsa, Philippe Pierre, Randall G Worth, Francis X Pizza
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58486 (2013)
We previously reported that leukocyte specific β2 integrins contribute to hypertrophy after muscle overload in mice. Because intercellular adhesion molecule-1 (ICAM-1) is an important ligand for β2 integrins, we examined ICAM-1 expression by murine
Externí odkaz:
https://doaj.org/article/bcd89d95202d43ab8060dc6c4b5dc48b
Autor:
Joseph S Marino, Jeffrey Iler, Abigail R Dowling, Streamson Chua, Jens C Bruning, Roberto Coppari, Jennifer W Hill
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48643 (2012)
Clinical research shows an association between polycystic ovary syndrome (PCOS) and chronic inflammation, a pathological state thought to contribute to insulin resistance. The underlying pathways, however, have not been defined. The purpose of this s
Externí odkaz:
https://doaj.org/article/066592c05d9440758442955d8c349a0e
Autor:
Kirsten V. Smith, Joseph E. Pero, Ralph A. Rivero, Donald O. Somers, Vipulkumar Kantibhai Patel, Agnes C. L. Martin, Rachel McMenamin, Sridhar Aravapalli, Finn P. Holding, Eric S. Manas, Lionel Trottet, Alison Jo-Anne Woolford, Neipp Christopher E, Lydia Y. W. Lee, Ranganadh Velagaleti, Sharna J. Rich, Ren Xie, Peng Li, Glyn Williams, Andrew M. Dodson, Brent W. Mccleland, Lee William Page, Joseph P. Marino, Pascal Grondin, Florent Potvain, Joseph E. Coyle, Christopher William Murray, Philip J. Day, Valerio Berdini
Publikováno v:
Journal of Medicinal Chemistry. 59:5356-5367
Elevated levels of human lipoprotein-associated phospholipase A2 (Lp-PLA2) are associated with cardiovascular disease and dementia. A fragment screen was conducted against Lp-PLA2 in order to identify novel inhibitors. Multiple fragment hits were obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7919286100bbcfc9e76bca6023c7c4
https://doi.org/10.1021/acs.jmedchem.6b00212
https://doi.org/10.1021/acs.jmedchem.6b00212