Application of the DP4 Probability Method to Flexible Cyclic Peptides with Multiple Independent Stereocenters: The True Structure of Cyclocinamide A

Autor: Jeffrey Aubé, Kelin Li, Joseph P. Konopelski, Jason K. Cooper, David Coppage

Publikováno v: Organic letters, vol 20, iss 14
Cooper, JK; Li, K; Aubé, J; Coppage, DA; & Konopelski, JP. (2018). Application of the DP4 Probability Method to Flexible Cyclic Peptides with Multiple Independent Stereocenters: The True Structure of Cyclocinamide A. Organic Letters, 20(14), 4314-4317. doi: 10.1021/acs.orglett.8b01756. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/7s54p7c3

Copyright © 2018 American Chemical Society. A DP4 protocol has been successfully utilized to establish the true structure of the natural product cyclocinamide A, a flexible cyclic peptide with four isolated stereocenters. Benchmarking the necessary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6faa75af76cd4b09dd76717bd4ef088f
https://escholarship.org/uc/item/7s54p7c3

Synthesis of a ferrocene-functionalized unsymmetrical benzo[b]thienyl-thienylethene photoswitch with a cyclopentene core

Autor: Shaowei Chen, Nathaniel B. Zuckerman, Joseph P. Konopelski, Xiongwu Kang

Publikováno v: Tetrahedron Letters. 54:1482-1485

A new and potentially general synthetic route toward unsymmetrical benzo[b]thienyl-thienylethene compounds is described, with specific focus on conjugation of a ferrocene to the benzo[b]thiophene subunit. The route proceeds in an overall yield of 17%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae5c56623464e7208c4efc35782cf8e1
https://doi.org/10.1016/j.tetlet.2013.01.033

Structural Determination of NSC 670224, Synthesis of Analogues and Biological Evaluation

Autor: Andrew S. Myers, R. Scott Lokey, Grant A. Hartzog, Nathaniel B. Zuckerman, Walter M. Bray, Tiffani K. Quan, Joseph P. Konopelski

Publikováno v: ChemMedChem. 7:761-765

Follow my lead! NSC 670224, previously shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related to that of tamoxifen (NSC 180973), breast cancer drug. The structure of NSC 6702

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b832cfe7b5b7cb1837db5a03d86c17
https://doi.org/10.1002/cmdc.201200038

Alkyne-Protected Ruthenium Nanoparticles

Autor: Nathaniel B. Zuckerman, Shaowei Chen, Joseph P. Konopelski, Xiongwu Kang, Wei Chen, Debraj Ghosh

Publikováno v: The Journal of Physical Chemistry C. 114:18146-18152

Stable ruthenium nanoparticles protected by 1-octynyl fragments were synthesized by a wet chemical method. Transmission electron microscopic measurements showed that the resulting particles exhibited an average core diameter of 2.55 ± 0.15 nm with w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e2c2e38361351d2f9dd6091b1db4b62
https://doi.org/10.1021/jp101053c

Janus nanoparticles: reaction dynamics and NOESY characterization

Autor: Joseph P. Konopelski, Shaowei Chen, Lauren E. Brown, Sulolit Pradhan

Publikováno v: Journal of Nanoparticle Research. 11:1895-1903

Janus nanoparticles were prepared by taking advantage of interfacial ligand exchange reactions of hydrophobic hexanethiolate-protected gold nanoparticles with hydrophilic 2-(2-mercaptoethoxy)ethanol (MEA). A monolayer of the particles was first forme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0f030960e37c8dc2ffe0969486b8407
https://doi.org/10.1007/s11051-008-9543-4