Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph P. Kolb"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Our immune system has evolved as a complex network of cells and tissues tasked with maintaining host homeostasis. This is evident during the inflammatory responses elicited during a microbial infection or traumatic tissue damage. These responses seek
Externí odkaz:
https://doaj.org/article/78826cddc66348b5b1fbff6a02f06eb9
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Our immune system has evolved as a complex network of cells and tissues tasked with maintaining host homeostasis. This is evident during the inflammatory responses elicited during a microbial infection or traumatic tissue damage. These responses seek
Autor:
Sing-Wai Wong, Ricardo J. Padilla, Joseph P. Kolb, Eui Ho Kim, Ching-Chang Ko, Lufei Wang, Bo-Wen Huang, Jennifer Martinez, Henry C. Tseng, Peng Xue, Thomas H. Oguin, Patricia A. Miguez, Xiangxiang Hu
Publikováno v:
Cell Death Differ
Genome-wide association studies (GWAS) have identified Optineurin (OPTN) as genetically linked to Paget's disease of the bone (PDB), a chronic debilitating bone remodeling disorder characterized by localized areas of increased bone resorption and abn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcfeb913ea5cb41515f0c0f08ae4b91
https://europepmc.org/articles/PMC7862615/
https://europepmc.org/articles/PMC7862615/
Autor:
Joseph P. Kolb, Erica Scappini, Laura M. DeGraff, Andrew Oberst, Jennifer Martinez, Payel Sil, Ginger W. Muse, Sing-Wai Wong, Sara A. Grimm, Courtney Tucker, Annelise G. Snyder, Zhao F
SummaryMajor Histocompatibility Complex I (MHC-I) molecules classically present peptides derived from endogenous antigens, but exogenous antigens can also gain access to the MHC-I machinery in dendritic cells (DCs), which can activate antigen-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846b5d35275b25b9d63d6d17c61a4495
Publikováno v:
Trends in Immunology. 38:705-718
The life of an organism requires the assistance of an unlikely process: programmed cell death. Indeed, both development and the maintenance of homeostasis results in the production of superfluous cells, that must eventually be disposed of. Furthermor
Autor:
Jennifer Martinez, Thomas H Oguin, Joseph P Kolb, Gregory Whitehead, Seddon Y Thomas, Ginger W Muse, Laura Miller DeGraff, Donald N. Cook
Publikováno v:
The Journal of Immunology. 204:234.7-234.7
Allergic airway inflammation (typified by atopic asthma) is a classic example of type 2 immunity, which can be triggered by non-microbial environmental stimuli, such as allergens. Importantly, type 2 immunity engages the entire affected tissue and ca
Autor:
Jennifer Martinez, Joseph P. Kolb
Publikováno v:
Immunity. 44(2):209-211
Phagocytes clear dying cells within an organism to prevent damaging inflammation and autoimmunity. In this issue of Immunity, Luo et al. (2016) describe how “find-me” signals from apoptotic cells induce erythropoietin signaling within macrophages
Autor:
Jörn Coers, Ryan Finethy, Joseph P. Kolb, Erin E. Zwack, Danielle M. Pilla-Moffett, Jennifer Martinez, Eric M. Feeley, Igor E. Brodsky, Anthony S. Piro
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Many invasive bacteria establish pathogen-containing vacuoles (PVs) as intracellular niches for microbial growth. Immunity to these infections is dependent on the ability of host cells to recognize PVs as targets for host defense. The delivery of sev
Autor:
Julian R. Smith, Jason W. Locasale, Joseph P. Kolb, Jennifer Martinez, Yueh Ming Loo, Andrew Oberst, Sigal B. Kofman, Geoffrey T. Norris, Annelise G. Snyder, Xia Gao, Brian P. Daniels, Michael Gale
Publikováno v:
Immunity. 50:64-76.e4
As long-lived post-mitotic cells, neurons employ unique strategies to resist pathogen infection while preserving cellular function. Here, using a murine model of Zika virus (ZIKV) infection, we identified an innate immune pathway that restricts ZIKV