Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joseph P. Kilroy"'
Publikováno v:
Photoacoustics, Vol 3, Iss 2, Pp 55-59 (2015)
We have developed reflection-mode multispectral photoacoustic microscopy (PAM) based on a novel optical–acoustic objective that integrates a customized ultrasonic transducer and a commercial reflective microscope objective into one solid piece. Thi
Externí odkaz:
https://doaj.org/article/72845b76c5c74b27970e2696b0881693
Publikováno v:
Photoacoustics
Photoacoustics, Vol 3, Iss 2, Pp 55-59 (2015)
Photoacoustics, Vol 3, Iss 2, Pp 55-59 (2015)
We have developed reflection-mode multispectral photoacoustic microscopy (PAM) based on a novel optical–acoustic objective that integrates a customized ultrasonic transducer and a commercial reflective microscope objective into one solid piece. Thi
Autor:
Douglas K. Bowles, Brian R. Wamhoff, Alexander L. Klibanov, John A. Hossack, Joseph P. Kilroy
Publikováno v:
Ultrasound in Medicine & Biology. 40:2458-2467
An intravascular ultrasound (IVUS) and microbubble drug delivery system was evaluated in both ex vivo and in vivo swine vessel models. Microbubbles with the fluorophore DiI embedded in the shell as a model drug were infused into ex vivo swine arterie
Publikováno v:
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 61:441-449
There is interest in examining the potential of modified intravascular ultrasound (IVUS) catheters to facilitate dual diagnostic and therapeutic roles using ultrasound plus microbubbles for localized drug delivery to the vessel wall. The goal of this
Autor:
Joseph P. Kilroy, Vamsi Meka, Brian Shin, Alexander L. Klibanov, Adam J. Dixon, John-Marschner Robert Rickel, John A. Hossack
Publikováno v:
2015 IEEE International Ultrasonics Symposium (IUS).
Therapeutic approaches that enhance thrombolysis by combining tissue plasminogen activator (tPA), ultrasound (US), and/or microbubbles (MBs) are known generally as sonothrombolysis techniques. To date, sonothrombolysis clinical trials and experimenta
Autor:
Johnny L. Chen, Adam J. Dixon, Joseph P. Kilroy, Michael Ragosta, John A. Hossack, Alexander L. Klibanov, Brian R. Wamhoff, Ali H. Dhanaliwala, Linsey C. Phillips
Publikováno v:
IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 62(9)
Intravascular ultrasound (IVUS) provides radiation-free, real-time imaging and assessment of atherosclerotic disease in terms of anatomical, functional, and molecular composition. The primary clinical applications of IVUS imaging include assessment o
Autor:
Joseph P. Kilroy, Brian R. Wamhoff, Alexander L. Klibanov, John A. Hossack, Ali H. Dhanaliwala, Douglas K. Bowles
Potent therapeutic compounds with dose dependent side effects require more efficient and selective drug delivery to reduce systemic drug doses. Here, we demonstrate a new platform that combines intravascular ultrasound (IVUS) and drug-loaded microbub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1f559f6b018d81fec1b7af220886aa
https://europepmc.org/articles/PMC4609231/
https://europepmc.org/articles/PMC4609231/
Autor:
Douglas K. Bowles, John A. Hossack, Ali H. Dhanaliwala, Joseph P. Kilroy, Brian R. Wamhoff, Alexander L. Klibanov
Publikováno v:
2014 IEEE International Ultrasonics Symposium.
An intravascular ultrasound (IVUS) catheter, optimized for microbubble-enhanced drug delivery, was used to reduce neointima formation in a swine model of balloon injury. In order to minimize neointima formation following balloon injury, rapamycin-loa
Autor:
John A. Hossack, Joseph P. Kilroy, Ali H. Dhanaliwala, Adam J. Dixon, Linsey C. Phillips, Brian R. Wamhoff, Alexander L. Klibanov, Johnny L. Chen
Publikováno v:
2013 IEEE International Ultrasonics Symposium (IUS).
An ideal solution for the diagnosis and treatment of a vascular disease must involve high-resolution imaging, quantitative characterization of the lesion, and the means to provide a comprehensive and versatile therapy that can be completed within a s
Publikováno v:
IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 58(12)
A selectable, dual-frequency, capacitive micro- machined ultrasonic transducer (CMUT) designed for both high-frequency imaging and low-frequency therapeutic effect is presented. A validated finite element analysis (FEA) CMUT model was used to examine